LOCUS       Tn6778                 17436 bp    DNA     linear       29-SEP-2020
DEFINITION  Raoultella ornithinolytica.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Raoultella ornithinolytica
  ORGANISM  Raoultella ornithinolytica
            Unclassified.
REFERENCE   1  (bases 1 to 17436)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of Tn6778
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17436)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..17436
                     /organism="Raoultella ornithinolytica"
                     /mol_type="genomic DNA"
     repeat_region   complement(1..16)
                     /gene="IRR_IS5"
     CDS             complement(147..1127)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS5 transposase"
                     /translation="MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPF
                     YPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRRFARLSLDSALPDR
                     TTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQR
                     DPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVS
                     ADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVE
                     HPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH"
     repeat_region   complement(1180..1195)
                     /gene="IRL_IS5"
     repeat_region   1277..1293
                     /gene="IRL_ISEc33"
     CDS             1378..2409
                     /gene="tnpA"
                     /codon_start=1
                     /product="ISEc33 transposase"
                     /translation="MPIIVPIPRGERRLMQKAIHKTRDKNHARRLTAMLMLHRGERVS
                     DVARTLCCARSSVGRWINWFTHSGIEGLKSLPAGRSRRWPFEHICTLLRELIKHSPGD
                     FGYQRSRWSTELLAIKINEITGCQLHAGTVRRWLPSAGLVWRRAAPTLRIRDPHKDEK
                     MAVIHKALDECSAEHPVFYEDEVDIHLNPKIGADWQLRGQQKRVVTPGQNEKYYLAGA
                     LHSGTGKVSYVGGNSKSSALFIALLKHLKATYRRAKTITLIVDNYIIHKSRETQRWLK
                     ANPKFRVIYQPVYSPWVNHVEQLWQALHDTITRNHQCRSMWQLLKKVRHFMETASPFP
                     GGKHGQAKV"
     repeat_region   2413..2429
                     /gene="IRR_ISEc33"
     CDS             complement(2881..3372)
                     /codon_start=1
                     /product="Sugar ABC transporter ATP-binding protein"
                     /translation="MNAFALEAEGISKFFPGVKALDNVSLRVRPGTVHALMGENGAGK
                     STLMKCLIGIYRPDKGAIRVKGEPVQFQDTMDALRSGISMIHQELNLVPHMTVAENIW
                     LGREPMKYGFVDHRQLARQTQELLNKLNIRLSADRLVGELSIAAQQMVEIAKAVSWNA
                     DTI"
     CDS             complement(3397..4320)
                     /codon_start=1
                     /product="Sugar ABC transporter substrate-binding protein"
                     /translation="MNIKKTVVASLIACMLPAVVMAKDISVGVSMALFDDNFLTILRT
                     AMQKEMQKEGVKSQMEDAKGDVSQQLQQVQNFIGQGVDAIIVNPVDTNAVKPIMDQAT
                     KAGIPLIFVNRRPQAQLTDKMAYVGSDSVLAGRLQMEALAKAMNGKGNVAILLGDLAN
                     ESTRDRTKGVEEVVAKYPDIKIVQKQTAKFMRNDAVDVVSNWMTSGEDIQAIASNNDE
                     MAIGALQALGKNPNHILIAGVDGTPDALQMLKNGKMIATIFQDAKGQGEGAVDAAIKL
                     ANGEKVEKVIDVPYQLITKDNMAEFINRNQK"
     CDS             complement(4770..5789)
                     /gene="lacI"
                     /codon_start=1
                     /product="LacI family transcriptional regulator"
                     /translation="MKSISLAALAKRIGVGVATVDRVLNERGGVSPETTRRVLQAARE
                     AGLKRILPEERRLPWQIEVFLSANDSRFFSRLTQDFADVADSLGYRRLTLHRTLVAES
                     SPEKLAKSLLRSSKKRHAIIVFGNEHPLVYEALRQCREANVPVITLVTDLPGAQRLCH
                     VGIDQQQAGRTAGMMMGLMAHQPGEVLMLCGRQDFSAHRSRIQGFREVISQRFPHLQL
                     GEVLAGEDNRQRIDRLLEEALNRNRDAVGIYNTGLGNSLVAQALARHRRYGKCCWITH
                     ERYSTTREQLAQGGMALTVDQNPHQHARLAVELALRHLETGYQPHLFRDGKVEFILYS
                     AENVD"
     CDS             5881..6900
                     /codon_start=1
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /translation="MENKMTCIRFALLGSGFIGQVHAANLARHERTVLAMVADAEPER
                     AKTLASRYGARATTVAEAISSDAIDAVLIASSTPSHAELLEAAARAGKAVYCEKPIDL
                     SLTRARQVVDRVLPLGVPVTVGFNRRFDASHQQLRRQVEAGVIGKIELVQMVCRASVM
                     PPLAYLRSSGGQMRDQAIHFFDLLRFLTGDEVTTVAAMGEALALPELAGIGDVDTSIL
                     MLRMRGGALAQLDNTRRTGHGYDERISLLGPEGVLESGSQASRGVTLWQGARCIQPGL
                     YPDWFSRVEESYYAHLDAFVRSSGGEEEPDLPGLLDGLRAQAIAEAAVLSLQQGQFVS
                     VEPLA"
     CDS             complement(6944..7975)
                     /gene="mviM"
                     /codon_start=1
                     /product="Myo-inositol 2-dehydrogenase"
                     /translation="MFPSQLPKPRHPAAAAIPSLRWAIIGPGWIAERFVKSLKELSRQ
                     RVVAVSSRTQQKADSFAARWGIPQAYAQVDEMLARPDIDAVYVATPHNHHFPDGLRVL
                     QAGKHVLIEKPFALNRREGAALKAEALKQGKLAMEAMWCDYAPKYDVIRQLLDDGALG
                     DLHTLLADHGEYFTSDHRIFNADLAGGPMMDLGSYLTSFSVMVGGVPQDIVARGRPAQ
                     RGINGQISMLFNWENGLQGLLNTTLFSNTPGGAVVAGRDATLVLDGQFYAPGNFTLAA
                     SQGGQILRWEEPRNRYDQLFYQAEHFAWCVGQGLTDSPIRPLTRVLENLSVMDEVRRQ
                     IGVIFNEER"
     CDS             8137..9009
                     /gene="blaOXY-2-8"
                     /codon_start=1
                     /product="Beta-lactamase OXY-2-8"
                     /translation="MIKSSWRKIAMLAAAVPLLLASGALWASTDAIHQKLTALEKRSG
                     GRLGVALINTADNSQILYRGDERFAMCSTSKVMAAAAVLKQSESNKEVVNKRLEINAA
                     DLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGPEKVTAFARSIGDA
                     TFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRAQLVTWLKGNTT
                     GGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQPQQDAKNRK
                     EVLAAAAKIVTEGL"
     CDS             complement(9110..9523)
                     /codon_start=1
                     /product="DNA breaking-rejoining protein"
                     /translation="MKKIKLIVGSVICASYLLASVLSMASDKINSNAVHFDKGSSGTI
                     IKSTVTGNDVNDFTLVAKAGQMMHISMTSQWPHPYFNVIAPDNNAIYNGSMSGDTFEQ
                     RLAVSGQYTVRVYQMGGARDEGKTSGYALTFKITD"
     CDS             complement(9860..11377)
                     /gene="lysS"
                     /codon_start=1
                     /product="Lysyl-tRNA synthetase"
                     /translation="MSEQQAQGADEAIDLNNELKTRREKLAALREQGVAFPNDFRRDH
                     TSDQLHAEFDGKENDELTSLNVEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLAEGVYNEQFKKWDLGDIIAARGKLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNEESRHTFKVRSQILAAMRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQTVLGKTEVPYGDQVFDFGKPFEKLTMREAIK
                     KYRPETEMADLDNFDAAKALAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFQDQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPQK"
     CDS             complement(11490..11675)
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="-
                     LPGSPAKAFTPRAGDRQPQQRSDKPLLAPFTEQEEDILASAEAEDKKVLLKRWLSEIS
                     RN"
     repeat_region   12234..12237
                     /gene="DR_ISKpn26"
     repeat_region   12238..12261
                     /gene="IRL_ISKpn26"
     CDS             12306..13286
                     /gene="tnpA"
                     /codon_start=1
                     /product="ISKpn26 transposase"
                     /translation="MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMTAVIEPF
                     YPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDR
                     TTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQR
                     DPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVS
                     ADAGYQGAPQREELAEVDVDWLIAERPGKVKTLKQHPRKNKTAINIEYMKASIRARVE
                     HPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ"
     repeat_region   13411..13434
                     /gene="IRR_ISKpn26"
     repeat_region   13435..13438
                     /gene="DR_ISKpn26"
     CDS             13533..14636
                     /gene="ompC"
                     /codon_start=1
                     /product="Outer membrane protein C precursor"
                     /translation="MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKIDGLHYF
                     SDDKSVDGDQTYMRIGVKGETQINDQLTGYGQWEYNVQANNVEGSDKQSWTRLAFAGL
                     KFGDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRANGVATYRNSDFFG
                     LVDGLNFALQYQGKNGSVSGEGQTNNGRGWNKQNGDGFGTAITYDIWEGISAGFAYSH
                     SKRTDDQNAAGLVGRGKYAETYTGGLKYDANNIYLAAEYTQTYNATRFSGDSVSGYAN
                     KAQNFEVVAQYQFDFGLRPSVAYLQSKGKDIEGFGDQDLLKYVDVAATYYFNKNMSAY
                     VDYKINLVDDNRFTSAAGISTDDIVALGLVYQF"
     CDS             14695..15408
                     /codon_start=1
                     /product="RepFIB associated resolvase"
                     /translation="MMDNKPLNKKELESIFLTSGAFNPKGLYLGEGFRKQALELGFPP
                     YILPTEINIVLHYSPELSVRTFVSTLWNTGASLTEVIHLERKSFVFKSPRPYVKVLSS
                     ETESLSLDNDNRLSPRRKIPLLSPYYIAQVKLLIATLKIAGNTCGDSTKPRRIWDVDN
                     FIATSWIDNAIKHARLDGVIFPVEVTPDAIKHAFAMNMLILGVEPSIVMKLMGFKRNK
                     WLEIYLKVKCLIMSLERDM"
     CDS             complement(15618..16166)
                     /gene="apnZ"
                     /codon_start=1
                     /product="Aquaporin Z"
                     /translation="MAYAVGHISGGHFNPAVTLGLWAGGRFPAKDVIGYIIAQVVGGI
                     IAAAILYVVASGKAGFDATASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHG
                     STDKSAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFW
                     VMPIIGGILGGLIYRTLLSSDK"
     repeat_region   complement(16242..16257)
                     /gene="IRR_IS5"
     CDS             complement(16388..17368)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS5 transposase"
                     /translation="MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPF
                     YPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRRFARLSLDSALPDR
                     TTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQR
                     DPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVS
                     ADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVE
                     HPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH"
     repeat_region   complement(17421..17436)
                     /gene="IRL_IS5"
ORIGIN      
        1 ggaaggtgcg aataagcggg gaaattcttc tcggctgact cagtcatttc atttcttcat
       61 gtttgagccg attttttctc ccgtaaatgc cttgaatcag cctatttaga ccgtttcttc
      121 gccatttaag gcgttatccc cagtttttag tgagatctct cccactgacg tatcatttgg
      181 tccgcccgaa acaggttggc cagcgtgaat aacatcgcca gttggttatc gtttttcagc
      241 aaccccttgt atctggcttt cacgaagccg aactgtcgct tgatgatgcg aaatgggtgc
      301 tccaccttgg cccggatgct ggctttcatg tattcgatgt tgatggccgt tttgttcttg
      361 cgtggatgct gtttcaaggt tcttaccttg ccggggcgct cggcgatcag ccagtccaca
      421 tccacctcgg ccagctcctc gcgctgtggc gccccttggt agccggcatc ggctgagaca
      481 aattgctcct ctccatgcag cagattaccc agctgattga ggtcatgctc gttggccgcg
      541 gtggtgacta ggctgtgggt caggccactc ttggcatcga caccaatgtg ggccttcatg
      601 ccaaagtgcc actgattgcc tttcttggtc tgatgcatct ccggatcgcg ttgctgctct
      661 ttgttcttgg tcgagctggg tgcctcaatg atggtggcat cgaccaaggt gccttgagtc
      721 atcatgacgc ctgcttcggc cagccagcga ttgatggtct tgaacaattg gcgggccagt
      781 tgatgctgct ccagcaggtg gcggaaattc atgatggtgg tgcggtcagg caaggcgcta
      841 tccagggata accgggcaaa ccgacgcatg gaggcgattt cgtacagagc atcttccatc
      901 gcgccatcgc tcaggttgta ccaatgctgc atgcagtgaa tgcgtagcat ggtttccagc
      961 ggataaggtc gccggccatt accagccttg gggtaaaacg gctcgatgac ttccaccatg
     1021 ttttgccatg gcagaatctg ctccatacgg gacaagaaaa tctcttttct ggtctgacgg
     1081 cgcttactgc tgaattcact gtcggcgaag gtaagttgat gactcatgat gaaccctgtt
     1141 ccatggctcc agatgacaaa catgatctca tatcagggac ttgttcgcac cttcctaagc
     1201 gtcggcatgg ttctagcgat catatgtcac cgacagaata tgaaaaccag tattatcaac
     1261 ggctcggaag tgtctaaata gctgcgcgga atagtagatc actgaaaggg aactcagccc
     1321 ggattgtgcg atctgatcaa tcgccaaacc aaccaaaatc accaaccgga ctgagcgatg
     1381 ccgatcatag taccaatacc ccgtggcgaa cgacgcctga tgcagaaagc tattcataaa
     1441 acgcgtgata aaaatcatgc ccgcagactc acggccatgc tgatgcttca tcggggtgaa
     1501 cgggtcagcg atgttgccag aactctctgt tgtgcccgtt catccgttgg tcgctggatt
     1561 aactggttta cgcactcagg tattgaaggc ctgaaatcct tacccgcagg gcgctcccga
     1621 cgctggcctt ttgaacatat ctgcaccctg ttacgtgagc tgataaagca ttctcccggc
     1681 gattttggtt atcaacgttc acgctggagc accgaattac tggcaataaa aatcaatgag
     1741 ataaccggtt gccagttaca tgcaggaacc gttcgccgct ggttgccatc tgcggggctt
     1801 gtatggcgca gggccgcgcc aactctgcgt atccgtgacc cacataaaga tgaaaagatg
     1861 gcggtaatcc acaaagcgct ggatgaatgc agcgcagagc atccggtatt ttatgaagat
     1921 gaagtggata tccaccttaa tcctaaaatc ggtgcggact ggcagttgcg cggacagcag
     1981 aaacgggtag tgacgccggg gcagaacgaa aaatactatc tggccggcgc actgcacagt
     2041 ggcacgggta aagtcagcta cgtgggcggc aacagcaaaa gttcagcgct gtttatcgct
     2101 ctgctgaagc acctgaaagc cacttatcgg cgggcgaaaa caatcacgct gatcgttgat
     2161 aactacatta tccataaaag ccgcgaaaca cagcgctggt tgaaagcaaa tcccaagttc
     2221 agggtaattt accagccggt ttactcgccg tgggtgaatc atgtggaaca gctatggcag
     2281 gcacttcatg acacgataac ccgtaatcat cagtgccgct caatgtggca gttactgaaa
     2341 aaggtccgcc attttatgga aaccgccagc ccattccccg gaggaaaaca tggtcaggca
     2401 aaagtgtagc ggtattaggc gcagctattt agattatccg tggcgattca ggctttttta
     2461 tgtccgttac tattagcata atcactacct acatcagggc tgtgccttaa cacgcatgac
     2521 gttaaaggcg gtgtgtgcaa aactgattag cagatagccg cagaccggga gcgaaacatc
     2581 cttgcggctg agcgctgcgt caatacctac ggcaatggac gacaactaag cgacaataca
     2641 ttttctgctg taacgtcgat cacgtttaac gctggttgcg ccagtatgca gaaatcaact
     2701 ctgtttaatt acctgcgaca gggaaagata actagtgcct gcaaccagtt cccacgctgg
     2761 ggtatacgac ggaggaaaaa tccttcccgg cctggtgact cgtcgcgcag cggaaaagca
     2821 gctctgtctg gatggtgtga aatgaatctg atttgcttcg tcattgctgc gtttcttgcc
     2881 ttagatggta tccgcattcc acgaaaccgc tttggcaatc tccaccatct gctgggcggc
     2941 gatgcttaat tcccctacca ggcgatcggc ggataaacga atattcagtt tattcagtag
     3001 ttcctgagtc tgccgggcaa gctggcgatg atcgacgaaa ccgtatttca tcggctcgcg
     3061 gccgagccag atattttccg ccaccgtcat atgcggtacc agattaagct cctgatggat
     3121 catcgagatc ccggagcgca gcgcgtccat cgtatcctga aactggaccg gctccccttt
     3181 gacgcggatc gcgcccttat cgggacggta gatcccgatc aggcatttca tcagcgtgga
     3241 tttcccggcg ccgttttcgc ccatcagcgc gtgcaccgtc cccggacgca cgcgtaatga
     3301 gacgttgtcg agcgccttca cgccggggaa gaatttgctg atcccttcgg cttcaagtgc
     3361 aaaagcgttc atacttcacc tccgtaccct gaatgactat ttctggttgc gattgatgaa
     3421 ttcagccatg ttgtctttgg tgatcagctg gtaagggacg tcgatgacct tttccacttt
     3481 ttcgccattg gccagcttaa tagcggcatc taccgcgcct tcgccctgcc ctttggcatc
     3541 ctggaaaatc gtggcgatca tcttgccgtt tttaagcatt tgcagggcat ctggcgttcc
     3601 gtccaccccg gcaatcagga tatggttggg gtttttcccc agcgcctgca gcgcgccgat
     3661 ggccatttca tcgttattgg aggcgatcgc ctgaatgtct tcgccgctgg tcatccagtt
     3721 gctgactacg tcaacggcgt cgttacgcat aaatttggcg gtctgcttct gcacgatttt
     3781 gatatcgggg tatttcgcca ccacctcttc gacccctttg gtccggtcgc gggtcgattc
     3841 attcgccagg tcgccgagca gaatggcgac gttgcccttg ccgttcatcg ctttggctag
     3901 cgcttccatc tgtaagcgcc ccgccagcac ggagtcggag ccgacgtagg ccattttatc
     3961 ggtcagctgc gcctgcggac gacggttaac gaagatcagc ggaatgcccg ctttggtcgc
     4021 ctggtccata atcggtttga ccgcgttggt atcgaccggg ttaacgataa tggcgtcgac
     4081 gccctggcca ataaaattct gcacctgctg tagctgctgc gagacgtcgc ccttcgcatc
     4141 ttccatctgg gacttcacgc cctctttttg catctctttt tgcatggcgg tgcgcagaat
     4201 ggtcaggaag ttgtcatcaa aaagcgccat agaaacaccg accgaaatat ctttcgccat
     4261 cacgaccgct ggcagcatgc aggctatcaa agaggcaaca accgttttct tgatattcat
     4321 agttgatcct ttattcacag gtacatcggt taggtaaggt aaaatgaaaa attagtttca
     4381 ttaattgtgc attaagcgcc tgctttttca gcgtttcgga aaaacaggct tcgcgctacg
     4441 tcatttttta atgccgaccg ccatcacaaa attcagttgt tttaaaatga ctttctgaaa
     4501 catcagtcca tttatcacga ggtaaaaatt acagaccgtt tatttcatta acaacacata
     4561 tgaaacgttt ataagtaaat aaccgaaatg aaaattttaa aactgcgtgt taacagaact
     4621 ttgacacaca tctaacattg acgcataaat gcgcaaaaaa tgagaggcag gcgacggttt
     4681 gccgcccggc gcggcgatag cggcagcggt ttaaaacggg acaggagata cggtgtaaaa
     4741 agggatgtcg cccggcaggc cgcgggcgct cagtcgacgt tttcagcgct atagaggata
     4801 aactcgacct tgccgtcacg aaagagatgg ggctgatagc cggtttccag gtggcgcagg
     4861 gccagctcca ccgccagcct ggcatgctga tgaggatttt gatcgaccgt caacgccatc
     4921 ccaccctgcg ccagctgttc gcgggtggtg ctatagcgtt catgagtaat ccaacagcac
     4981 ttaccataac ggcgatggcg ggccagcgcc tgcgccacca gactattgcc cagaccggta
     5041 ttgtagatgc ccaccgcgtc gcggttacgg ttcagggctt cttccagcaa acggtcgatc
     5101 cgctgccggt tatcctcacc cgccagcacc tcaccaagct gcagatgcgg aaagcgctgg
     5161 cttatcacct cgcgaaatcc ctgaatccgc gagcggtggg cgctgaaatc ctgacgaccg
     5221 cagagcatca acacttcccc gggctgatgg gccatcagcc ccatcatcat gcccgcggta
     5281 cgtcccgcct gctgctgatc gattcccaca tggcaaagcc tctgcgcgcc gggcaggtcg
     5341 gtgaccagcg taattaccgg tacgtttgct tcgcgacact ggcgcagggc ttcatagacc
     5401 agcggatgtt cgttgccgaa gacaattatc gcatggcgct ttttactgct gcgaagaagg
     5461 cttttcgcca gtttttccgg ggaggattcc gccaccagcg tgcggtgcag cgtcagtcgg
     5521 cgatagccaa ggctatccgc cacgtcggcg aaatcctgcg tcaggcgaga gaaaaagcgc
     5581 gagtcgttag cgctcaggaa cacttcgatt tgccagggca gacgacgttc ttccggcaaa
     5641 atacgcttta aaccggcttc acgcgccgcc tgcagcaccc ggcgcgtggt ttccggcgac
     5701 acgccgccgc gttcgttaag cacccggtca accgtcgcca cgcccacgcc gatccgttta
     5761 gccagcgccg ccagtgaaat gcttttcatc gttcccctca cccatgatgg aaatccatca
     5821 aaacgcccgt gttggtcagt gtagcaaaca gattaatttg gcaacgctaa atccctcttt
     5881 atggagaaca aaatgacctg cattcgtttt gcgttattag gcagcggttt tataggccag
     5941 gttcacgccg ccaacctcgc tcgccatgag cgaaccgttc tggccatggt ggcagacgcc
     6001 gagcccgagc gggcgaaaac gctggcctcc cgctacggcg cgcgggcaac caccgtcgcc
     6061 gaggccatca gtagcgatgc cattgatgcg gtgctcatcg ccagctcgac cccttcacat
     6121 gcggaactgc tggaggcagc cgcgcgcgcc gggaaggccg tttactgcga aaaaccgatc
     6181 gacctttcgc tgacccgcgc gcgccaggtt gtcgacaggg ttttgccgct cggcgtgccg
     6241 gtgaccgtgg gctttaaccg ccgctttgac gccagccacc agcagctgcg tcgccaggtc
     6301 gaggctggcg ttatcggtaa aattgaactg gtgcagatgg tgtgccgggc atcggttatg
     6361 ccgccgctgg cgtatctgcg cagctccggc ggccagatgc gcgaccaggc aatccacttt
     6421 ttcgatctgc tgcgttttct taccggcgat gaagtgacaa cggttgccgc catgggagag
     6481 gcgctggcgc tgccggagct cgccgggatc ggcgatgtcg atacctccat tctcatgctg
     6541 cggatgcgcg gcggcgcgct ggcgcagctg gacaacaccc ggcgcaccgg ccacggctac
     6601 gatgaacgca tcagcctgct cggcccggag ggcgtactgg agtccggcag tcaggcctcg
     6661 cgcggcgtga cgctgtggca gggagcgcgc tgcattcagc ccggcctcta tccggactgg
     6721 ttcagccgcg tcgaggagtc gtactacgcg catctggatg cttttgtccg ctcgtcaggc
     6781 ggagaagagg agccggacct gccggggctg ctggacgggc tgcgggcgca ggctatcgcc
     6841 gaagccgccg tgctttccct gcagcaaggg caatttgtca gcgtcgaacc gctggcgtaa
     6901 aaaagccccg tatgcggtcg gcatacgggg caacggcgcg ccgttaacgc tcctcgttaa
     6961 atattacgcc aatctgccgc cgcacttcat ccatgacgct caggttttcc agaactctgg
     7021 tcagcgggcg aatcggcgaa tccgtgagcc cttgccccac gcaccaggca aaatgttcgg
     7081 cctgataaaa cagctggtcg tagcggttac gcggctcttc ccagcgcagt atctgtcccc
     7141 cctggctggc ggcgagggta aaattccccg gcgcatagaa ttgcccgtca aggaccaggg
     7201 tcgcgtcgcg cccggccacc accgcgccgc ccggcgtatt gctgaatagc gtggtgttga
     7261 gcaatccctg taagccgttt tcccagttaa acagcatcga aatttgccca ttgatgcccc
     7321 tttgggcggg gcgcccgcgg gcgacaatgt cctgcggcac gccgccgacc atcacgctga
     7381 atgaggtcag atagctgccg agatccatca tcggtccacc ggcaagatcg gcattaaaaa
     7441 tgcgatgatc cgaagtaaaa tattcaccgt gatcggcgag cagcgtatgc agatcgccca
     7501 gcgcgccgtc atccagcagc tggcgaatca cgtcatattt cggcgcgtaa tcgcaccaca
     7561 tcgcctccat cgccagcttc ccctgtttca gggcttctgc ttttagcgcc gcgccttccc
     7621 gccggttcag cgcaaacggc ttttcaatca gtacatgttt gcccgcctgc agaacccgca
     7681 gcccgtccgg gaagtggtgg ttatgcgggg tggcaacgta aaccgcatca atatccggtc
     7741 gcgccagcat ctcgtccacc tgagcgtaag cctgcgggat cccccagcgg gcggcaaagc
     7801 tatcggcctt ttgttgcgtc cgcgaggaga cggcaaccac ccgctggcgg ctgagctctt
     7861 ttaacgattt cacaaagcgc tcggcaatcc agccggggcc aataatggcc cagcgcagcg
     7921 aggggatcgc cgcagcggca ggatggcgcg gtttcggtaa ctgtgacggg aacatagcgg
     7981 ctccttattt ttatgggtct ggcgagacac tataagcagg cgctggaagg acaaatatcg
     8041 aattgatgat ggaattccat catcaataaa ttgcttgtca aaatagcggg agtcgcagat
     8101 aatccgctgc gacttatcac tctcaaggaa tcagaaatga taaaaagttc gtggcgtaaa
     8161 attgcaatgc tagccgccgc cgttccgctg ctgctggcga gcggcgcact gtgggccagt
     8221 accgatgcta tccatcagaa gctgacagct ctcgagaagc gttcaggcgg caggttgggc
     8281 gtggcgctaa tcaacacggc agataattct caaatcttat atcgcggcga cgagcgtttt
     8341 gccatgtgca gcaccagtaa agtgatggcc gccgccgcgg tattaaaaca gagcgaaagc
     8401 aataaagagg tggtaaataa aaggctggag attaacgcag ccgatttggt ggtctggagt
     8461 ccgattaccg aaaaacatct ccagagcgga atgacgctgg ctgagctaag cgcggcgacg
     8521 ctgcaatata gcgacaatac ggcgatgaat ctgatcatcg gctaccttgg cgggccggaa
     8581 aaagtcaccg ccttcgcccg cagtatcggc gatgccacct ttcgtctcga tcgtacggag
     8641 cccacgctga ataccgccat cccgggcgat gagcgtgata ccagcacgcc gctggcgatg
     8701 gctgaaagcc tgcgcaagct gacgcttggc aatgcgctgg gcgaacagca acgcgcccag
     8761 ttagtcacct ggctgaaagg caataccacc ggcgggcaaa gcattcgcgc gggcctgcct
     8821 gaaagctggg tggtcggcga taaaaccggc gccggagatt acggcaccac caatgatatt
     8881 gcggttatct ggccggaaaa tcacgctccg ctggtattag tcacctactt tacccagccg
     8941 cagcaggatg cgaaaaaccg caaagaggtg ttagccgcag cggcaaaaat cgtgaccgaa
     9001 gggctttaag ccgggaacag gtccgttctg caacactctg tactctgctc ccgggggcgg
     9061 cgcttaacgc gccgcccccg ggacagcctg aacagacagc cgccaaatat tagtcggtga
     9121 ttttaaacgt cagcgcataa ccgctggttt taccttcatc acgcgcgccg cccatctgat
     9181 agacccgcac cgtatattga ccgctgacgg ccagacgctg ctcaaaggta tctccgctca
     9241 ttgaaccgtt ataaatggca ttattatcag gcgcgataac attaaaataa ggatgcggcc
     9301 actggctcgt catgctgata tgcatcatct ggcccgcttt cgccaccagc gtaaaatcat
     9361 tgacatcgtt cccggtcaca gtacttttta ttatcgtacc gctgctgcct ttatcaaaat
     9421 ggacagcatt actgtttatt ttatcacttg ccattgataa cactgacgct aataaataac
     9481 ttgcacagat cacgctgcca acaattagct ttattttttt catttaatta acaccttatg
     9541 ttttttatgc gcgctgttat agcatataag atgcatggag taagctactt ctaaatagag
     9601 tcccgtattt aaggtttaaa atccggagcg gtattttaaa aaatcgctat gcctgttcat
     9661 cagaaaaggg gggggaattt cgtacgtaat acagcctcgg agatcgctgc gatagttttc
     9721 ctaatcggag ttctgctccc ttataacctg ctgtaaagca gcgggttaac tcttgatgaa
     9781 atgcgagtgc aggatgaaag tcgctttgca agtgctaaaa aaccccggca ggccggggtt
     9841 ttgctttcac gccacgcaat cacttctgcg ggcgcattgc cgggaacagg atcacgtcgc
     9901 ggatggtatg gctgttggta aacagcatca ccatgcggtc gataccaatg cccaggccag
     9961 cggtcggcgg caggccatat tccagcgcgg tgacgtagtc ttcgtcatag aacatcgctt
    10021 cgtcatcccc cgccgctttg gcgttgacct gatcctggaa acgctgcgcc tgatcttccg
    10081 catcgttaag ctcgctaaag ccgttgccga tttcacgccc gccgataaag aactcgaagc
    10141 ggtcggtgat ttccgggttc acgtcgttac ggcgcgccag cggcgaaacc tccgccggat
    10201 actcggtgat aaaggtcggc tggatcagat gcgcttccgc gacttcatcg aaaatttcgg
    10261 tgacgatacg ccccagtccc cagctcttct caacgtgaat accgatggat tccgccagcg
    10321 cttttgccgc atcgaagtta tccagatccg ccatctcggt ttccggacgg tatttcttga
    10381 tcgcttcgcg catggtcagt ttttcaaacg gcttgccgaa gtcgaacacc tggtcgccgt
    10441 acggcacttc ggttttaccc agcacggtct gcgccagcgt gcggaacaga gactcggtca
    10501 gttcgatcag atctttatag tccgcatagg ccatatagag ttccatcatg gtgaactctg
    10561 ggttatgacg tacggaaata ccttcgttac ggaagttacg gttgatctcg aatacccgtt
    10621 caaagccgcc gaccaccagc cgtttcagat acagctccgg cgcgatgcgc agatacatat
    10681 ccagatcgag cgcattatga tgggtgataa acggacgcgc ggaagcgccg ccggggatca
    10741 cctgcatcat cggggtttcc acttccataa agccgcgcgc aaccatgaac tgacgcatgg
    10801 cggcgaggat ctgcgaacgc accttgaagg tgtggcgcga ctcttcgttg gaaatcagat
    10861 ccagatagcg ctgacgatag cgcgcttcct gatcctgcag gccgtgaaac ttgtccggca
    10921 gcgggcgtaa tgccttggtc agcaggcgca gctcggtaca gtgaatggag agttcgccgg
    10981 tttgggtttt aaacagctta ccgcgggcgg cgatgatgtc gccgagatcc catttcttaa
    11041 actgttcgtt gtagacgcct tccgccagat cgtcgcgcgc gacgtacagc tgaatgcggc
    11101 cgccgacgtc ctgtaaagta acgaaagagg ctttacccat aatgcggcga gtcatcatgc
    11161 ggccagccac ggagacctcg acgttcagag aggtgagctc gtcgttttcc ttaccatcga
    11221 actccgcatg aagctggtca gaagtgtggt cacggcgaaa atcgttcggg aacgccacgc
    11281 cctgctcgcg cagcgcggcc agtttttcac gacgggtttt cagttcatta ttaaggtcaa
    11341 ttgcctcatc ggcaccttgt gcttgttgtt cagacatgtt ggttcctcat aaccctgctt
    11401 gcaaacttgc ttcgataatt gaaccaggtg ctatccagcg cggcctgtcc cggtgacgac
    11461 accaaagaat aatcttcagg atcctggctt caattccggc tgatttcact cagccatcgc
    11521 ttcagtaaca cttttttatc ttcggcttcc gcgctcgcca gaatatcctc ctcctgttca
    11581 gtaaagggtg caaggagcgg cttgtcgctc cgctgttgag gttgccgatc cccggctcgc
    11641 ggcgtaaacg ccttagccgg gctaccaggc agcacaattt tgtcgccccg gtaagcgcag
    11701 cgcgaccggg gggagatttc ccgcaaagcc gcatctgtcg ccagccgaag gctaggcgcc
    11761 gcctccgggt ggtaatgatg cgtggccgtg gtttctggct gttggaataa tcatgtcatg
    11821 agccgcgtga ccgccattat cagcgctgtg gttatgctca acggcgagag agtggacgat
    11881 gatcgcttgc aactcgatac caatccgctg ctgatggatg cgatcagcgc ggtgaaatat
    11941 ttagctggca aaatggagca attgcaaaac atcattgcag agctgaaggc atcaaatgca
    12001 tgattggtat cgctaatttt attctccaga catccacata tcagcctctt cgaacatctc
    12061 caggataact ctgccaattt gttctttttc atgcttactg gcatctgtat agcccctcag
    12121 ggcatgtcca ttcctattgc tatgtgtttt ggttatgaga cacgagatga cgtgttatgc
    12181 attcctttta caatatgtta caaaatgtag gtgtattcac agggaacttt taactaggga
    12241 aggtgcgaac aagttcctga tatgagatca tcatattcat ccggagcgca tcccagaggg
    12301 acatcatgag ccatcaactc accttcgccg atagtgaatt cagcactaag cgccgtcaga
    12361 cccgaaaaga gattttcctc tcccgcatgg agcagattct gccatggcag aatatgaccg
    12421 ctgtcatcga gccgttttat cccaaggcgg gcaatggccg acggccctat ccgctggaga
    12481 ccatgctgcg tattcactgc atgcagcatt ggtacaacct gagcgacggt gccatggaag
    12541 atgccctgta cgaaatcgcc tccatgcgcc tgtttgcccg attatccctg gatagcgccc
    12601 tgccggatcg caccaccatc atgaatttcc gccacctgct cgagcagcat caactggccc
    12661 gtcaattgtt caagaccatc aatcgctggc tggccgaagc aggcgtcatg atgacccaag
    12721 gcactttggt ggatgccacc atcattgagg cacccagctc taccaagaac aaagagcagc
    12781 aacgcgatcc ggagatgcat cagaccaaga aaggcaatca gtggcacttt ggcatgaagg
    12841 cccacattgg tgtcgatgcc aagagtggcc tgacccacag cctggtcacc accgcggcca
    12901 acgagcatga cctcaatcag ctgggtaatc tgcttcatgg agaggagcaa tttgtctcag
    12961 ccgatgccgg ctaccaagga gcgccacagc gcgaggagct ggccgaggtg gatgtggact
    13021 ggctgatcgc cgagcgtccc ggcaaggtaa aaaccttgaa gcagcatccg cgcaagaaca
    13081 aaacggccat caacatcgaa tacatgaaag ccagcatccg tgccagggtg gagcacccgt
    13141 ttcgcatcat caagcggcag ttcggcttcg tgaaagccag atacaagggg ctgctgaaaa
    13201 acgataacca actggcgatg ttattcaccc tggccaacct gtttcgggtg gaccaaatga
    13261 tacgtcagtg ggagagatct cagtaaaaac cggaaataac gccagaaatg gtggaaaaaa
    13321 tagcctaaat aggctgattc gatgtgtttg cgggaaaaaa aatcggccca gatccgcgaa
    13381 attttaatca gcgagtcagc ttgggaagaa atgacctgct tattcgcacc ttccctagct
    13441 tacagcatga gaaggctgga tttttttgtg tatagataat tatacaatga cagcccgata
    13501 cgcagtggca aatataaaac gagggttcaa ccatgaaagt taaagtacta tccctcttgg
    13561 taccggctct gctggtagca ggtgcagcaa atgcggctga aatttataac aaagatggca
    13621 acaaattaga cctgtacggt aaaattgatg gcttgcatta cttttctgat gacaagagcg
    13681 tcgatggcga tcagacctac atgcgtatcg gcgtgaaggg cgaaacccag attaatgacc
    13741 aactgactgg ctacggtcag tgggaataca acgttcaggc gaacaacgtt gaaggttctg
    13801 acaagcagtc ctggactcgt ctggcatttg ctggtctgaa attcggcgac gtgggctctt
    13861 tcgactacgg tcgtaactac ggcgttgtct acgacgtaac ttcctggact gacgttctgc
    13921 cagagtttgg cggtgacact tatggctctg acaacttcat gcagcagcgt gctaatggtg
    13981 ttgcaaccta tcgtaactct gacttcttcg gtctggttga cggcctgaac tttgcgctgc
    14041 agtaccaggg taaaaacggt agtgtaagtg gtgaaggcca gactaacaat ggtcgcggct
    14101 ggaacaaaca gaacggtgat ggcttcggaa cagcgatcac ttatgatatt tgggaaggca
    14161 tcagcgcagg ttttgcatac tctcattcta aacgaactga tgaccagaat gctgcaggtc
    14221 tggttggtcg aggtaaatac gcagaaactt acactggtgg cttgaaatat gacgcgaaca
    14281 atatttactt ggctgcggag tatacccaaa cttataatgc gactcgtttc agtggtgatt
    14341 ccgtcagtgg ttatgctaat aaagcacaaa actttgaagt ggttgcacag taccagttcg
    14401 acttcggtct gcgtccgtcc gtggcatacc tgcagtccaa aggtaaagac atcgaaggtt
    14461 tcggcgatca ggatctgctg aaatatgttg atgtagccgc gacctactac ttcaacaaaa
    14521 acatgtctgc ttatgttgat tataaaatca atttggtgga tgacaatcgt ttcaccagtg
    14581 ctgctggcat ctctactgat gacattgtcg cacttggttt agtatatcag ttttaattat
    14641 ttaccaaaca ccggccttgg tggccggtgt ttgtgtcgat atgatggata agatatgatg
    14701 gataataagc cattaaataa aaaagaactt gaaagtattt tccttacttc aggggctttt
    14761 aatccgaagg ggttgtatct gggggagggg tttcgtaaac aggcccttga attgggtttt
    14821 cctccatata ttttacccac agagattaac attgttttgc attattcgcc tgagttgagt
    14881 gtacgaactt ttgtttctac tttatggaat actggtgctt cattaactga agtgattcat
    14941 ttagaacgga agtcttttgt ttttaaatct cctcgcccat atgttaaagt attaagttct
    15001 gaaactgaat cattgtcgtt agataacgat aatagattgt ctccccgccg gaaaattcct
    15061 ttactttccc catattatat agctcaagtt aagttattga ttgctacttt gaaaatagcg
    15121 ggtaatactt gcggcgattc caccaaacct aggaggatat gggatgtgga caatttcatt
    15181 gcgacatcat ggatagataa tgctattaaa catgccagat tggatggcgt gatttttcca
    15241 gtagaagtca cgccggatgc aattaaacac gcatttgcaa tgaatatgct gatcttggga
    15301 gttgagccat caatagtaat gaagttaatg gggtttaaaa ggaataagtg gcttgaaata
    15361 tatttgaaag ttaaatgctt aattatgtcc ttggagaggg atatgtgata aaaagcgatg
    15421 ctttggatca tgttgaggtg ctcgaaattg cgacacactc gatcaactat acgaggctgg
    15481 ataattgtac ggtttaaccc cccactcccc acccatacag ttgtatgcaa ggcctgcaga
    15541 gtggggagga ctgaagattt tttcgatggc tggcgtgaat atggaatgat ctgcagtcgt
    15601 atagagtttt taattattca tttatcactg ctgagcaaag tgcgataaat taaaccgccc
    15661 agtatcccac caatgattgg catgacccag aataaccata attgttgcaa tgcccaaccg
    15721 ccctgaaaaa tcgctaccgc agtgctacgc gccgggttta ccgacgtgtt ggtgaccgga
    15781 atgctgatca ggtgaataag cgtcagtgcc agtccaatgg cgataggggc gaagccggca
    15841 ggagcgcttt tatccgtgga accgtgaata accagcagga agccacatgt caggacaatc
    15901 tctatcacaa tggcggaaag cattgagaag ccgcccggag agtgttcgcc ataaccgttc
    15961 gaagcgaacc cgctagcggt ggcgtcgaag cccgctttac cgctggcgac aacatacaga
    16021 atagcggcgg cgataatacc gccgacgact tgggcgataa tataaccaat tacgtctttg
    16081 gccgggaaac gacctccagc ccataaacct aaagtcactg ccgggttaaa atgtccgccg
    16141 gaaatatgac cgacggcata tgccatggtt aataccgtta aaccgaaggc cagcgccacc
    16201 ccagcaaaac caattcctaa tcccgggaat gctgccgcaa gggaaggtgc gaataagcgg
    16261 ggaaattctt ctcggctgac tcagtcattt catttcttca tgtttgagcc gattttttct
    16321 cccgtaaatg ccttgaatca gcctatttag accgtttctt cgccatttaa ggcgttatcc
    16381 ccagttttta gtgagatctc tcccactgac gtatcatttg gtccgcccga aacaggttgg
    16441 ccagcgtgaa taacatcgcc agttggttat cgtttttcag caaccccttg tatctggctt
    16501 tcacgaagcc gaactgtcgc ttgatgatgc gaaatgggtg ctccaccttg gcccggatgc
    16561 tggctttcat gtattcgatg ttgatggccg ttttgttctt gcgtggatgc tgtttcaagg
    16621 ttcttacctt gccggggcgc tcggcgatca gccagtccac atccacctcg gccagctcct
    16681 cgcgctgtgg cgccccttgg tagccggcat cggctgagac aaattgctcc tctccatgca
    16741 gcagattacc cagctgattg aggtcatgct cgttggccgc ggtggtgact aggctgtggg
    16801 tcaggccact cttggcatcg acaccaatgt gggccttcat gccaaagtgc cactgattgc
    16861 ctttcttggt ctgatgcatc tccggatcgc gttgctgctc tttgttcttg gtcgagctgg
    16921 gtgcctcaat gatggtggca tcgaccaagg tgccttgagt catcatgacg cctgcttcgg
    16981 ccagccagcg attgatggtc ttgaacaatt ggcgggccag ttgatgctgc tccagcaggt
    17041 ggcggaaatt catgatggtg gtgcggtcag gcaaggcgct atccagggat aaccgggcaa
    17101 accgacgcat ggaggcgatt tcgtacagag catcttccat cgcgccatcg ctcaggttgt
    17161 accaatgctg catgcagtga atgcgtagca tggtttccag cggataaggt cgccggccat
    17221 taccagcctt ggggtaaaac ggctcgatga cttccaccat gttttgccat ggcagaatct
    17281 gctccatacg ggacaagaaa atctcttttc tggtctgacg gcgcttactg ctgaattcac
    17341 tgtcggcgaa ggtaagttga tgactcatga tgaaccctgt tccatggctc cagatgacaa
    17401 acatgatctc atatcaggga cttgttcgca ccttcc
//
