LOCUS       Tn6384                 25996 bp    DNA     linear       29-SEP-2020
DEFINITION  Klebsiella pneumoniae.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Unclassified.
REFERENCE   1  (bases 1 to 25996)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of Tn6384
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25996)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..25996
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
     repeat_region   1..22
                     /gene="IRL_Tn6384-5'"
     repeat_region   complement(26..37)
                     /gene="IRR_IS5075"
     CDS             complement(278..1282)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS5075 transposase"
                     /translation="MENIALIGIDLGKNSFHIHCQDHRGKAVYRKKFTRPKLIEFLAT
                     CPATTIAMEACGGSHFMARKLAELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAAS
                     RPSMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISR
                     LSTLLEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCV
                     GTLTASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLL
                     VQCARVFIQKLEHQSGKLADWVRELLCRKSNFVVTCALANKLARIAWALTARQQTYEA
                     "
     repeat_region   complement(1331..1342)
                     /gene="IRL_IS5075"
     repeat_region   1350..1365
                     /gene="IRL_Tn6384-3'"
     CDS             complement(1361..4333)
                     /gene="tnpA"
                     /codon_start=1
                     /product="Tn6384 transposase"
                     /translation="MPRRSILSATERESLLALPDAKDELIRHYTFNETDLSVIRQRRG
                     AANRLGFAVQLCYLRFPGTFLGVDEPPFPPLLRMVAAQLKMPVESWSEYGQREQTRRE
                     HLVELQTVFGFKPFTMSHYRQAVHTLTELALQTDKGIVLASALVENLRRQSIILPAMN
                     AIERASAEAITRANRRIYAALTDSLLSPHRQRLDELLKRKDGSKVTWLAWLRQSPAKP
                     NSRHMLEHIERLKSWQALDLPAGIERQVHQNRLLKIAREGGHMTPADLAKFEVQRRYA
                     TLVALAIEGMATVTDEIIDLHDRIIGKLFNAAKNKHQQQFQASGKAINDKVRMYGRIG
                     QALIEAKQSGSDPFAAIEAVMPWDTFAASVTEAQTLARPADFDFLHHIGESYATLRRY
                     APQFLGVLKLRAAPAAKGVLDAIDMLRGMNSDSARKVPADAPTAFIKPRWAKLVLTDD
                     GIDRRYYELCALSELKNALRSGDVWVQGSRQFKDFDEYLVPVEKFATLKLASELPLAV
                     ATDCDQYLHDRLELLEAQLATVNRMAAANDLPDAIITTASGLKITPLDAAVPDAAQAM
                     IDQTAMLLPHLKITELLMEVDEWTGFTRHFTHLKTSDTAKDKTLLLTTILADAINLGL
                     TKMAESCPGTTYAKLSWLQAWHIRDETYSTALAELVNAQFRQPFAGNWGDGTTSSSDG
                     QNFRTGSKAESTGHINPKYGSSPGRTFYTHISDQYAPFSAKVVNVGIRDSTYVLDGLL
                     YHESDLRIEEHYTDTAGFTDHVFGLMHLLGFRFAPRIRDLGETKLFIPKGDAAYDALK
                     PMISSDRLNIKQIRAHWDEILRLATSIKQGTVTASLMLRKLGSYPRQNGLAVALRELG
                     RIERTLFILDWLQSVELRRRVHAGLNKGEARNALARAVFFYRLGEIRDRSFEQQRYRA
                     SGLNLVTAAIVLWNTVYLERATSALRGNGTALDDTLLQYLSPLGWEHINLTGDYLWRS
                     SAKVGAGKFRPLRPLPPA"
     CDS             complement(4336..4893)
                     /gene="tnpR"
                     /codon_start=1
                     /product="Tn6384 resolvase"
                     /translation="MQGQRIGYVRVSSFDQNPERQLEGVQVARVFTDKASGKDTQRPE
                     LERLLAFVREGDTVVVHSMDRLARNLDDLRRIVQGLTQRGVRMEFVKEGLKFTGEDSP
                     MANLMLSVMGAFAEFERALIRERQREGIVLAKQRGAYRGRKKSLNSEQIAELKRRVAA
                     GDQKTLVARDFGISRETLYQYLRED"
     misc_recomb     4914..4988
                     /gene="truncated res-5'"
     repeat_region   4997..5021
                     /gene="IRi_In916"
     CDS             complement(5199..6212)
                     /gene="intI1"
                     /codon_start=1
                     /product="IntI1 integrase"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     misc_recomb     6293..6355
                     /gene="attI1"
     CDS             6379..7179
                     /gene="blaVIM-1"
                     /codon_start=1
                     /product="Class B beta-lactamase VIM-1"
                     /translation="MLKVISSLLVYMTASVMAVASPLAHSGEPSGEYPTVNEIPVGEV
                     RLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQ
                     IGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEAEGNEIPTHSLEGLSS
                     SGDAVRFGPVELFYPGAAHSTDNLVVYVPSANVLYGGCAVHELSSTSAGNVADADLAE
                     WPTSVERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVKAHKNRSVAE"
     misc_recomb     7188..7268
                     /gene="attC_blaVIM-1"
     CDS             7287..7841
                     /gene="aacA4'"
                     /codon_start=1
                     /product="Aminoglycoside 6'-N-acetyltransferase AacA4'"
                     /translation="-
                     TNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQES
                     VTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQSLANASQLGKGLGTKL
                     VRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQ
                     AFERTRSDA"
     misc_recomb     7798..7907
                     /gene="attC_aacA4'"
     CDS             7912..8706
                     /gene="aphA15"
                     /codon_start=1
                     /product="Aminoglycoside phosphotransferase AphA15"
                     /translation="MTVALDEVSELKNLLSPLLDECTFEEVEYGQSDARVIRVLFPDR
                     NTAYLKYASGSSAQEILQEHQRTRWLRTRALVPEVISYVSTSTVTILLTKALIGHNAA
                     DAADADPVIVVAEMARALRDLHSISPDDCPFDERLHLRLKLASGRLEAGLVDEEDFDH
                     ARQGMLARDVYEQLFIQMPGAEQLVVTHGDACPENFIFQGNAFVGFIDCGRVGLADKY
                     QDLALASRNIDAVFGPELTNQFFIEYGEPNPNIAKIEYYRILDEFF"
     misc_recomb     8712..8813
                     /gene="attC_aphA15"
     CDS             8823..9614
                     /gene="aadA1b"
                     /codon_start=1
                     /product="Aminoglycoside adenyltransferase AadA1b"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKP
                     HSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
                     DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGRIAPKDVAADWAMERLPA
                     QYQPVILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_recomb     9572..9626
                     /gene="attC_aadA1b"
     CDS             9667..10299
                     /gene="catB2"
                     /codon_start=1
                     /product="Chloramphenicol acetyltransferase CatB2"
                     /translation="MTNYFESPFKGKLLTEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLLPDRDDVDQLIIGSFCSIGSGAAFIMAGNQGHRYDWVSSFPFFYMNEEPAFAKSV
                     DAFQRAGDTVIGSDVWIGSEAMIMPGIKIGHGAVIGSRALVAKDVEPYTIVGGNPAKS
                     IRKRFSEEEISMLLDMAWWDWPLEQIKEAMPFLCSSGIASLYRRWQGTSA"
     misc_recomb     10294..10359
                     /gene="attC_catB2"
     CDS             10468..10815
                     /gene="qacEDl"
                     /codon_start=1
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     misc_feature    10809..11141
                     /gene="truncated sul1"
                     /product="Truncated dihydropteroate synthase"
     repeat_region   complement(11035..11048)
                     /gene="IRR_IS26"
     CDS             complement(11087..11791)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS26 transposase"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     repeat_region   complement(11841..11854)
                     /gene="IRL_IS26"
     CDS             11871..12371
                     /gene="pdk"
                     /codon_start=1
                     /product="Phosphatidylinositol kinase"
                     /translation="MRLQQWATENIKKLLYLAGDDAVINYGKMRLEFLQKALAQDTSG
                     DFCFRVLHPEVSGPPDMKKASAGYRDFIIGNRALLDLVNSAGEGAPVAHYSADEIQSL
                     FSAQIQGSVDKYGDSFLTDDPYVLAEDKLQTCQMEIDLMADVLRAPPRESAELIRYVF
                     ADEWPE"
     CDS             12521..13162
                     /gene="catA2"
                     /codon_start=1
                     /product="Chloramphenicol acetyltransferase CatA2"
                     /translation="MNFTRIDLNTWNRREHFALYRQQIKCGFSLTTKLDITALRTALA
                     KTGYKFYPLMIYLISRAVNQFPEFRMAMKDNELIYWEQSDPVFTVFHKETETFSALSC
                     RYFPDLSEFMAGYNAVTAEYQHDTRLFPQGNLPENHLNISSLPWVSFDGFNLNITGND
                     DYFSPVFTMAKFQQEGDRVLLPVSVQVHHAVCDGFHAARFINTLQLMCDNILK"
     repeat_region   complement(13254..13267)
                     /gene="IRR_IS26"
     CDS             complement(13306..14010)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS26 transposase"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     misc_feature    complement(14057..14755)
                     /gene="truncated intI1"
                     /product="Truncated intI1 integrase"
     repeat_region   complement(14060..14073)
                     /gene="IRL_IS26"
     misc_recomb     14836..14898
                     /gene="attI1"
     CDS             15002..15601
                     /gene="aacA4cr"
                     /codon_start=1
                     /product="Fluoroquinolone acetylating aminoglycoside
                     acetyltransferase AacA4CR"
                     /translation="MSNAKTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRSH
                     IVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGR
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRA
                     IRCYEKAGFERQGTVTTPYGPAVYMVQTRQAFERTRSDA"
     misc_recomb     15596..15667
                     /gene="attC_aacA4cr"
     CDS             15732..16562
                     /gene="blaOXA-1"
                     /codon_start=1
                     /product="Beta-lactamase OXA-1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCF
                     LLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGM
                     EIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLT
                     EAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGA
                     GFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
                     "
     misc_recomb     16582..16671
                     /gene="attC_blaOXA-1"
     CDS             16700..17332
                     /gene="catB3"
                     /codon_start=1
                     /product="Chloramphenicol acetyltransferase"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVEPYAIVGGNPAKK
                     IKKRFTDEEISLLLEMEWWNWSLEKIKAAMPMLCSSNIVGLHKYWLEFAV"
     misc_recomb     17327..17386
                     /gene="attC_catB3"
     CDS             17417..17869
                     /gene="arr3"
                     /codon_start=1
                     /product="Rifampin ADP-ribosylating transferase Arr3"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFED
                     GRILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGN
                     PTQSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
     misc_recomb     17876..17989
                     /gene="attC_arr3"
     CDS             18092..18439
                     /gene="qacEDl"
                     /codon_start=1
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             18433..19272
                     /gene="sul1"
                     /codon_start=1
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     CDS             19400..19900
                     /gene="orf5"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHA
                     GRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAE
                     RLELEI"
     CDS             19924..20211
                     /gene="orf6"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MSGWDGPVASRSLAVRPRCLGCARGCRYPPLPSSTLDNAAAVIA
                     ADARAGLFGPVRLARPSACLGEISGGRINGGASPPFVRVKAEDSSLKNIRL"
     repeat_region   complement(20223..20247)
                     /gene="IRt_In37"
     repeat_region   20346..20359
                     /gene="IRL_IS6100"
     CDS             20407..21171
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS6100 transposase"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     repeat_region   21212..21225
                     /gene="IRR_IS6100"
     misc_feature    21226..21492
                     /gene="truncated tnpA"
                     /product="Truncated IS6100 transposase (pseudogene)"
     repeat_region   21533..21546
                     /gene="IRR_IS6100"
     repeat_region   21674..21698
                     /gene="IRt_In37"
     misc_recomb     21696..21740
                     /gene="truncated res-3'"
     CDS             complement(21730..21942)
                     /gene="urf2"
                     /codon_start=1
                     /product="Urf2 protein"
                     /translation="MNANAPNTASCTTCCVCCKEIPLDAAFTPEGAEYVEHFCGLDCY
                     ERFQARAKAATESDIAPVPGGSQPSD"
     CDS             complement(22008..22244)
                     /gene="merE"
                     /codon_start=1
                     /product="Mercuric resistance protein MerE"
                     /translation="MNSPEHLPSETHKPITGYLWGALAVLTCPCHLPILAIVLAGTTA
                     GAFIGEHWGIAALTLTGLFVLSVTRLLRAFKGRS"
     CDS             complement(22241..22606)
                     /gene="merD"
                     /codon_start=1
                     /product="Mercuric resistance protein MerD"
                     /translation="MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDD
                     TALQRLRFVRAAFEAGIGLDALARLCRALDAADGDGASAQLAVLRQLVERRREALASL
                     EMQLAAMPTEPAQHAESLP"
     CDS             complement(22624..24306)
                     /gene="merA"
                     /codon_start=1
                     /product="Mercuric reductase MerA"
                     /translation="MYLNITGMTCDSCATHVKDALEKVPGVLSALVSYPKGSAQLATD
                     PGTSPEALTAAVAGLGYKATPADAPSTSARGRLLGKALGWLGGGDKAGGDGDGLHVAV
                     IGSGGAAMAAALKAVEQGANVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESP
                     FDSGIAATVPAIDRSKLLAQQQARVDELRHAKYEGILDSNPAITVLHGEARFKDDQSL
                     AVRLNDGGERVVAFDRCLVATGASPAVPPIPGLKESPYWTSTEALVSDTIPERLAVIG
                     SSVVALELAQAFARLGSKVTILARNTLFFREDPAIGEAVTAAFRAEGIKVLEHTQASQ
                     VAHVDGEFVLTTGYGEIRADQLLVATGRAPNTRSLALEAAGVAANAQGAIVIDKGMRT
                     STPHIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVG
                     YSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSGRLIGVQAVAPEAG
                     ELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG"
     CDS             complement(24345..24752)
                     /gene="merC"
                     /codon_start=1
                     /product="Mercuric transport protein MerC"
                     /translation="MGLITRIADKAGALGSVVSAMGCAACFPAIASLGAAIGLGFLQE
                     YEGLFISKLLPLFAVVALLANALGWLSHRQWYRSLLGMVGPAIVLAAMLLFFGNWWTA
                     NLLYVVLALMIGVSIWDLLSPANRRCELPPKHG"
     CDS             complement(24780..25055)
                     /gene="merP"
                     /codon_start=1
                     /product="Mercuric transport protein periplasmic component
                     MerP"
                     /translation="MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCSTCPITVKKAI
                     SKVEGVSKIDVTFETREAVVTFDDAKTSVQKLTKATGDAGYPSSVKQ"
     CDS             complement(25071..25436)
                     /gene="merT"
                     /codon_start=1
                     /product="Mercuric transport protein MerT"
                     /translation="MSEPQKSEPQNGRGALFAGGLAAILASACCLGPLVLIALGFSGA
                     WIGNLTVLEPYRPIFIGAALVALFFAWRRIYRPAQACKPGEVCAIPQVRATYKLIFWI
                     VAALVLVALGFPYVMPFFY"
     CDS             25508..25963
                     /gene="merR"
                     /codon_start=1
                     /product="Mercuric regulatory protein MerR"
                     /translation="MQINFENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIR
                     RYGEADVTRVRFVKSAQRLGFSLDEIAELLRLEDGTHCEEASGLAEHKLKDVREKMAD
                     LARMEAVLSELVCACHARKGNVSCPLIASLQDGTKLAASARGSHGVTTP"
     repeat_region   25959..25996
                     /gene="IRR_Tn6384"
ORIGIN      
        1 ggggtcgtct cagaaaacgg aatctatggt cactcccgtt tttgcaacac cgattttgac
       61 gacaagttgg cttgcttgaa tctatccggc gtctgaatgg gattttattc ccgcgcctcg
      121 atgagttccg cgcctgatga acctccagaa aatatacggc ttcaatgagc ctttccgttt
      181 tacaggttcc tcaacaggcc ggtgggccgt tagtatcatc aatattagta ttcgcaaaac
      241 cagatgaatg attgtttaaa ctggtgtatt tctgccttta tgcttcgtaa gtttgctgtc
      301 gcgccgtcag tgcccaggct attctggcca gcttgtttgc cagagcacag gtgacgacaa
      361 agttgctttt ccgacacaac aactccctga cccagtcggc caacttgcca gactggtgtt
      421 ccagtttttg tatgaatacc ctggcacact gaaccaacaa agttcggatc tttttgttgc
      481 cccgcttgct aatccctaac aatgtcgtcc gacctcccgt gctgtactgt cggggtacca
      541 gccctgttgc cgccgcaaag tcacggctgc tggcgtactg cttcccgtcg ccaatctcag
      601 ttgaaatagt actggcagtc agcgttccaa cgcagggaat actcagcaag cgctgtccaa
      661 cctcatcttc gtccaacttt cgtttcaact gagattccag atctttaatc tgctcaacaa
      721 gatagtgata atgctgttgt aatttcagca gtaactggct gagataaaga ggcaaactac
      781 tgtcctcaag aagggtactc agtcgactaa taacggcagc acctcgcgga acgctgatac
      841 caaattccag cagaaaagca tgcatctgat tagttgtttt caccttatcc tgaaccaggg
      901 attcacggac acgatgcaga gctcgcattg cctgctgaga ttcggttctg ggctgcacga
      961 aacgcataga tggacgtgat gctgcttcac agatagcttc agcatcaacg aagtcatttt
     1021 tgttgctttt aacgaatggg cggacaaatt gcggtgatat cagctttgga aaatgcccta
     1081 actctgccag cttgcgtgcc ataaagtgag aaccgccaca ggcttccatc gcgatggttg
     1141 ttgccgggca tgtcgccaga aattcgatta gctttggtcg ggtgaatttt ttacggtaaa
     1201 cggccttccc acgatgatcc tgacaatgaa tatggaaaga gttcttaccc agatcgatac
     1261 caataagcgc aatgttttcc atgatggttc tccgaatgaa agcctgtcct cagcatagta
     1321 ctgggaagga gggagtgacc atctcattaa ataaagcacg ctaagccggt ggcagcggtc
     1381 gcaatggcct aaacttcccc gcaccgacct tggcgctgct gcgccatagg taatcgccgg
     1441 tcaggttgat gtgctcccac cccagcggcg acagatattg caacaatgtg tcgtccagcg
     1501 ccgtgccgtt gccacgcaaa gcactggtgg cacgctccag atataccgtg ttccacaaca
     1561 cgatggccgc cgtcaccaga ttgaggccgc tggcccggta gcgctgctgc tcaaaactgc
     1621 ggtcgcggat ttcacccaat cggtagaaga agaccgccct ggccagcgcg ttgcgcgcct
     1681 cgcccttatt cagccccgca tggacgcggc ggcgcagctc cacgctttgc agccaatcca
     1741 aaatgaacag cgtgcgctcg atgcgcccca gctcgcgcaa cgccacggcc aagccgttct
     1801 ggcgcgggta gctgccgagt ttgcgcagca tcagcgaagc cgttaccgtg ccttgcttga
     1861 tggaggtggc cagccgcaga atttcatccc aatgggcgcg tatttgcttg atgttcagcc
     1921 tgtcgctgct aatcatcggc ttgagcgcgt cataggcggc atcgcccttg gggatgaata
     1981 gcttggtttc gcccaagtca cggatacgcg gcgcgaagcg aaatcccagc aaatgcatca
     2041 agccaaacac gtgatcggtg aagcctgccg tgtcggtgta gtgttcctcg atgcgcaagt
     2101 ccgactcgtg gtacagcagg ccatcaagca cgtaagttga atcacgaatg cccacgttga
     2161 ccaccttggc actgaagggc gcgtactggt cggagatatg ggtgtagaaa gtccgtcctg
     2221 gactgcttcc atacttcggg ttgatatgac cagtgctttc tgctttgctg ccggttctga
     2281 agttctggcc gtccgacgat gacgtggtgc cgtcacccca gttgccggcg aagggttgcc
     2341 gaaactgcgc attcaccagc tcggccagcg ccgtcgaata ggtttcatcg cggatgtgcc
     2401 aggcttgcag ccaagacagc ttggcgtagg tggtgccagg gcaggactcg gccattttgg
     2461 tcagacccag gttgatcgcg tcggccagga tcgtcgtcaa cagcaaggtt ttgtccttgg
     2521 ccgtgtcgct ggtcttcagg tgtgtgaagt ggcgggtgaa gcccgtccat tcatcgacct
     2581 ccatcagcaa ctcggtgatt ttgaggtgcg gcagcagcat agctgtctgg tcgatcatgg
     2641 cttgcgcggc gtctggtact gccgcgtcca gcggcgtgat cttcaggcct gacgcggtgg
     2701 tgatgatggc atccggtaag tcgttggccg cagccatgcg gttgactgtg gcgagttgcg
     2761 cctccaacaa ttccaaccgg tcatgcaggt attggtcgca gtcggtggcc actgccagcg
     2821 gcaattcgct ggccagcttc aaagtggcga acttctcgac cggcaccagg tattcgtcga
     2881 agtccttgaa ctggcgagaa ccctgcaccc agacatcacc ggagcgcagc gcgttcttca
     2941 gctccgacag ggcgcataac tcgtagtaac gccggtcgat gccgtcgtcg gtcagaacca
     3001 gctttgccca gcgcggcttg atgaatgcgg ttggcgcatc ggcgggcacc ttgcgcgcgc
     3061 tgtcgctgtt catgccgcgc agcatgtcga tggcatcgag cacacccttg gcggcgggcg
     3121 cagcccgcaa tttgagcacg cccaggaact gcggcgcgta gcggcgtagc gtggcatagc
     3181 tttcaccgat gtggtgcagg aaatcaaagt cggcaggccg cgccaatgtt tgcgcttcgg
     3241 tgacgctggc ggcgaaggtg tcccagggca taacggcctc gatggcggcg aacggatcgc
     3301 tgccgctttg cttggcctca atcaacgctt gaccgatgcg cccatacatc cgcaccttgt
     3361 cgttgatcgc cttgccggaa gcctggaact gctgctgatg cttgttcttg gccgcgttga
     3421 acagcttgcc gatgatgcga tcgtgaaggt cgatgatttc atcggtgacg gtggccatgc
     3481 cttcgatggc cagcgctacc agcgtggcat agcgtcgttg cacctcgaac tttgccagat
     3541 cagcaggcgt catatggcca ccttcacgag cgattttgag caggcggttc tggtgaacct
     3601 gccgctcgat gcctgcgggc agatcaagtg cttgccagga tttcaggcgc tcaatatgtt
     3661 cgagcatgtg gcgagagttc ggtttggcag gcgactggcg cagccatgcc agccacgtca
     3721 ctttactgcc gtccttgcgc ttgagaagtt cgtccaggcg ctgacggtgg ggtgataaca
     3781 aagaatcggt cagcgccgcg taaatgcgtc ggttggcacg ggtgatggcc tcggcgcttg
     3841 cgcgctcgat ggcattcatg gcgggcagga taatgctctg ccgccgcaga ttctcgacaa
     3901 gtgcgctcgc cagcacgatg cctttgtcgg tctgcaaggc cagctcggtc aatgtatgca
     3961 cggcttgccg atagtggctc atggtgaagg gcttgaaccc aaaaaccgtt tgcagctcga
     4021 ccaagtgctc ccgccgtgtc tgttcgcgct ggccgtactc gctccaactt tccactggca
     4081 tcttgagttg cgcggccacc atgcgcaaca ggggcggaaa cggaggctca tcgacgccca
     4141 aaaaggtgcc agggaatcgc aagtagcaaa gctgcacagc gaagcccaat cgattcgcgg
     4201 cgccgcgacg ctgacggatc accgacaggt cggtttcgtt gaacgtgtag tgccgtatca
     4261 gttcgtcttt ggcatctggc agtgccagca ggctttcgcg ctcggtggcg gacaggattg
     4321 agcggcgtgg catggtcagt cttcccgcag gtactggtac aaggtttcgc ggctgatgcc
     4381 gaagtcacgg gccaccaagg ttttttggtc gcctgccgca actcgccgtt tcaactcggc
     4441 aatttgttcg ctgttcagcg atttctttcg tccccggtag gcaccgcgct gcttggccag
     4501 cacgattccc tcgcgctgac gttcgcggat cagggcgcgc tcgaactcag cgaaggctcc
     4561 catgaccgac agcatcagat tggccatcgg tgagtcctcg ccggtgaact tcagcccttc
     4621 tttgacgaac tccatgcgca cgccccgttg tgtcagccct tggacgatgc ggcgcaggtc
     4681 atcaaggttg cgtgccagcc tgtccatgct atgcaccacc acggtgtcgc cctcgcggac
     4741 gaaggccagc agcctttcca gctcgggacg ctgggtgtcc ttgccagaag ccttgtcggt
     4801 gaacacccgc gccacctgaa caccctccaa ttgccgttcc gggttctggt cgaagctgct
     4861 gacgcggaca tagccgatgc gttgaccttg caagatgcct ccaaaggcaa aagtgtcagg
     4921 atgaaatcta ttacctttga cggaatatgt caatcaatag gaaatttaac tctattctga
     4981 catcgtttgc acatggtgtc gttttcagaa gacggctgca ctgaacgtca gaagccgact
     5041 gcactatagc agcggagggg ttggatccat caggcaacga cgggctgctg ccggccatca
     5101 gcggacgcag ggaggacttt ccgcaaccgg ccgttcgatg cggcaccgat ggccttcgcg
     5161 caggggtagt gaatccgcca ggattgactt gcgctgccct acctctcact agtgaggggc
     5221 ggcagcgcat caagcggtga gcgcactccg gcaccgccaa ctttcagcac atgcgtgtaa
     5281 atcatcgtcg tagagacgtc ggaatggccg agcagatcct gcacggttcg aatgtcgtaa
     5341 ccgctgcgga gcaaggccgt cgcgaacgag tggcggaggg tgtgcggtgt ggcgggcttc
     5401 gtgatgcctg cttgttctac ggcacgtttg aaggcgcgct gaaaggtctg gtcatacatg
     5461 tgatggcgac gcacgacacc gctccgtgga tcggtcgaat gcgtgtgctg cgcaaaaacc
     5521 cagaaccacg gccaggaatg cccggcgcgc ggatacttcc gctcaagggc gtcgggaagc
     5581 gcaacgccgc tgcggccctc ggcctggtcc ttcagccacc atgcccgtgc acgcgacagc
     5641 tgctcgcgca ggctgggtgc caagctctcg ggtaacatca aggcccgatc cttggagccc
     5701 ttgccctccc gcacgatgat cgtgccgtga tcgaaatcca gatccttgac ccgcagttgc
     5761 aaaccctcac tgatccgcat gcccgttcca tacagaagct gggcgaacaa acgatgctcg
     5821 ccttccagaa aaccgaggat gcgaaccact tcatccgggg tcagcaccac cggcaagcgc
     5881 cgcgacggcc gaggtcttcc gatctcctga agccagggca gatccgtgca cagcaccttg
     5941 ccgtagaaga acagcaaggc cgccaatgcc tgacgatgcg tggagaccga aaccttgcgc
     6001 tcgttcgcca gccaggacag aaatgcctcg acttcgctgc tgcccaaggt tgccgggtga
     6061 cgcacaccgt ggaaacggat gaaggcacga acccagttga cataagcctg ttcggttcgt
     6121 aaactgtaat gcaagtagcg tatgcgctca cgcaactggt ccagaacctt gaccgaacgc
     6181 agcggtggta acggcgcagt ggcggttttc atggcttgtt atgactgttt ttttgtacag
     6241 tctatgcctc gggcatccaa gcagcaagcg cgttacgccg tgggtcgatg tttgatgtta
     6301 tggagcagca acgatgttac gcagcagggc agtcgcccta aaacaaagtt atgccgcacc
     6361 cacccctatg gagtcttgat gttaaaagtt attagtagtt tattggtcta catgaccgcg
     6421 tctgtcatgg ctgtcgcaag tccgttagcc cattccgggg agccgagtgg tgagtatccg
     6481 acagtcaacg aaattccggt cggagaggtc cgactttacc agattgccga tggtgtttgg
     6541 tcgcatatcg caacgcagtc gtttgatggc gcggtctacc cgtccaatgg tctcattgtc
     6601 cgtgatggtg atgagttgct tttgattgat acagcgtggg gtgcgaaaaa cacagcggca
     6661 cttctcgcgg agattgaaaa gcaaattgga cttcccgtaa cgcgtgcagt ctccacgcac
     6721 tttcatgacg accgcgtcgg cggcgttgat gtccttcggg cggctggggt ggcaacgtac
     6781 gcatcaccgt cgacacgccg gctagccgag gcagagggga acgagattcc cacgcattct
     6841 ctagaaggac tctcatcgag cggggacgca gtgcgcttcg gtccagtaga gctcttctat
     6901 cctggtgctg cgcattcgac cgacaatctg gttgtatacg tcccgtcagc gaacgtgcta
     6961 tacggtggtt gtgccgttca tgagttgtca agcacgtctg cggggaacgt ggccgatgcc
     7021 gatctggctg aatggcccac ctccgttgag cggattcaaa aacactaccc ggaagcagag
     7081 gtcgtcattc ccgggcacgg tctaccgggc ggtctagact tgctccagca cacagcgaac
     7141 gttgtcaaag cacacaaaaa tcgctcagtc gccgagtagc agatgcggca taacaaatcg
     7201 ttggagcggg acttttgcta cgcaggctgc gcctactccg caaaagcccc tcaactcagg
     7261 cgttaggcat cacaaagtac agcatcgtga ccaacagcaa cgattccgtc acactgcgcc
     7321 tcatgactga gcatgacctt gcgatgctct atgagtggct aaatcgatct catatcgtcg
     7381 agtggtgggg cggagaagaa gcacgcccga cacttgctga cgtacaggaa cagtacttgc
     7441 caagcgtttt agcgcaagag tccgtcactc catacattgc aatgctgaat ggagagccga
     7501 ttgggtatgc ccagtcgtac gttgctcttg gaagcgggga cggatggtgg gaagaagaaa
     7561 ccgatccagg agtacgcgga atagaccagt cactggcgaa tgcatcacaa ctgggcaaag
     7621 gcttgggaac caagctggtt cgagcactgg ttgagttgct gttcaatgat cccgaggtca
     7681 ccaagatcca aacggacccg tcgccgagca acttgcgagc gatccgatgc tacgagaaag
     7741 cggggtttga gaggcaaggt accgtaacca ccccagatgg tccagccgtg tacatggttc
     7801 aaacacgcca ggcattcgag cgaacacgca gtgatgccta acccttccat cgagggggac
     7861 gtccaagggc tggcgccctt ggccgcccct catgtcaaac gttagaccgc tatgacagtc
     7921 gccctcgacg aagtatctga actaaagaat ttgctttcac ccttgttgga tgaatgcact
     7981 tttgaagaag ttgagtatgg tcagtcagat gctcgagtga ttcgagttct atttcctgat
     8041 cgcaataccg cgtatctaaa gtacgcctcc ggatcttctg ctcaagaaat tcttcaagag
     8101 catcagcgca ctagatggct cagaacacga gctctcgtac cggaagtgat ctcatatgtc
     8161 tcgacttcaa ctgtcaccat cctgttgaca aaagcattga ttggccacaa tgccgctgac
     8221 gccgcagatg cagatccagt tattgttgtt gcagagatgg cacgagcgtt acgcgacctc
     8281 cattcgatct cgcctgacga ttgcccattc gacgaaaggc tccacctgcg actgaagctg
     8341 gcttcgggcc gtttggaagc cgggttagtt gatgaggagg actttgatca cgcaaggcaa
     8401 ggcatgctgg cgcgggatgt ttacgagcaa ctttttatac aaatgcctgg agcggagcag
     8461 ctggtagtca cacatggcga cgcctgtccc gagaacttca tcttccaagg taatgccttc
     8521 gtcggcttca tagactgcgg tcgggtcggg cttgccgata agtatcaaga cctggcgctt
     8581 gcatcgagaa acattgacgc ggtatttgga ccagaactca ctaaccagtt cttcatcgag
     8641 tatggagagc caaatccgaa catagctaag attgagtact accggatctt ggatgagttc
     8701 ttctaagcgc ggtctaacaa ttcgttcaag ccgagatcgc ttcgcggccg cggagttgtt
     8761 ctgtaaattg tcacaacgcc gcggccgcaa agcgctccgg cttaactcag gcgttaaaca
     8821 tcatgaggga agcggtgatc gccgaagtat cgactcaact atcagaggta gttggcgtca
     8881 tcgagcgcca tctcgaaccg acgttgctgg ccgtacattt gtacggctcc gcagtggatg
     8941 gcggcctgaa gccacacagt gatattgatt tgctggttac ggtgaccgta aggcttgatg
     9001 aaacaacgcg gcgagctttg atcaacgacc ttttggaaac ttcggcttcc cctggagaga
     9061 gcgagattct ccgcgctgta gaagtcacca ttgttgtgca cgacgacatc attccgtggc
     9121 gttatccagc taagcgcgaa ctgcaatttg gagaatggca gcgcaatgac attcttgcag
     9181 gtatcttcga gccagccacg atcgacattg atctggctat cttgctgaca aaagcaagag
     9241 aacatagcgt tgccttggta ggtccagcgg cggaggaact ctttgatccg gttcctgaac
     9301 aggatctatt tgaggcgcta aatgaaacct taacgctatg gaactcgccg cccgactggg
     9361 ctggcgatga gcgaaatgta gtgcttacgt tgtcccgcat ttggtacagc gcagtaaccg
     9421 gcagaatcgc gccgaaggat gtcgctgccg actgggcaat ggagcgcctg ccggcccagt
     9481 atcagcccgt catacttgaa gctagacagg cttatcttgg acaagaagaa gatcgcttgg
     9541 cctcgcgcgc agatcagttg gaagaatttg ttcactacgt gaaaggcgag atcaccaagg
     9601 tagtcggcaa ataatacatg ttaggcgacg cgtggagtcg ctctagaatt ttcgggtaca
     9661 aattttatga cgaattattt tgagagtccc ttcaaaggga agcttctgac tgagcaggtg
     9721 aagaatccga acatcaaggt agggcggtat agctactatt ccggctatta ccatgggcac
     9781 tcgtttgatg attgtgctcg ctaccttcta ccagaccgtg atgacgttga tcagctgatt
     9841 atcggcagct tctgctccat cggatcaggc gcagctttta ttatggctgg gaatcaaggc
     9901 caccgatatg attgggtctc ttctttccct ttcttctaca tgaacgagga gcccgcgttt
     9961 gcaaaatcag tcgatgcatt ccagcgggct ggcgacacag ttataggaag tgatgtgtgg
    10021 atcggttcgg aggccatgat catgcccggg atcaagatcg ggcatggagc ggtgataggt
    10081 agccgcgctt tggttgccaa agacgtggaa ccctacacca tagtgggggg aaaccctgca
    10141 aagtcgatta ggaagcgctt ttctgaagaa gaaatttcta tgcttttaga tatggcttgg
    10201 tgggattggc cgctggaaca aatcaaggaa gcaatgcctt ttctttgttc gtctggcatt
    10261 gccagcctgt atcgtcgctg gcaaggcaca agcgcctaac aatacgctac acacggacaa
    10321 attactcgct gcgctcctaa tttgccggtg agcgtggcgt tagatgcact aagcacataa
    10381 ttgctcacag ccaaactatc aggtcaagtc tgcttttatt atttttaagc gtgcataata
    10441 agccctacac aaattgggag atatatcatg aaaggctggc tttttcttgt tatcgcaata
    10501 gttggcgaag taatcgcaac atccgcatta aaatctagcg agggctttac taagcttgcc
    10561 ccttccgccg ttgtcataat cggttatggc atcgcatttt attttctttc tctggttctg
    10621 aaatccatcc ctgtcggtgt tgcttatgca gtctggtcgg gactcggcgt cgtcataatt
    10681 acagccattg cctggttgct tcatgggcaa aagcttgatg cgtggggctt tgtaggtatg
    10741 gggctcataa ttgctgcctt tttgctcgcc cgatccccat cgtggaagtc gctgcggagg
    10801 ccgacgccat ggtgacggtg ttcggcattc tgaatctcac cgaggactcc ttcttcgatg
    10861 agagccggcg gctagacccc gccggcgctg tcaccgcggc gatcgaaatg ctgcgagtcg
    10921 gatcagacgt cgtggatgtc ggaccggccg ccagccatcc ggacgcgagg cctgtatcgc
    10981 cggccgatga gatcagacgt attgcgccgc tcttagacgc cctgtccgat cagaggcact
    11041 gttgcaaagt tagcgatgag gcagcctttt gtcttattca aaggccttac atttcaaaaa
    11101 ctctgcttac caggcgcatt tcgcccaggg gatcaccata ataaaatgct gaggcctggc
    11161 ctttgcgtag tgcacgcatc acctcaatac ctttgatggt ggcgtaagcc gtcttcatgg
    11221 atttaaatcc cagcgtggcg ccgattatcc gtttcagttt gccatgatcg cattcaatca
    11281 cgttgttccg gtacttaatc tgtcggtgtt caacgtcaga cgggcaccgg ccttcgcgtt
    11341 tgagcagagc aagcgcgcga ccataggcgg gcgctttatc cgtgttgatg aatcgcggga
    11401 tctgccactt cttcacgttg ttgaggattt tacccagaaa ccggtatgca gctttgctgt
    11461 tacgacggga ggagagataa aaatcgacag tgcggccccg gctgtcgacg gcccggtaca
    11521 gatacgccca gcggccattg accttcacgt aggtttcatc catgtgccac gggcaaagat
    11581 cggaagggtt acgccagtac cagcgcagcc gtttttccat ttcaggcgca taacgctgaa
    11641 cccagcggta aatcgtggag tgatcgacat tcactccgcg ttcagccagc atctcctgca
    11701 gctcacggta actgatgccg tatttgcagt accagcgtac ggcccacaga atgatgtcac
    11761 gctgaaaatg ccggcctttg aatgggttca tgtgcagctc catcagcaaa aggggatgat
    11821 aagtttatca ccaccgacta tttgcaacag tgccctgttt agagtactat atgcgcctgc
    11881 aacagtgggc caccgaaaat attaaaaaac tgctttatct cgcgggggat gacgcggtga
    11941 ttaattacgg gaaaatgcgg ctggaatttt tgcagaaagc actggcgcag gatacctccg
    12001 gtgacttctg ctttcgtgtg ctgcatccgg aagtgtctgg cccgccggat atgaaaaagg
    12061 cttccgccgg gtaccgtgac tttattatcg gtaacagagc gttgctggat ctggtgaatt
    12121 cagccggtga aggggctccg gttgcgcatt attccgctga tgaaattcag tcattatttt
    12181 cggcacaaat acaggggtcg gtggataaat acggcgatag tttcctgacg gatgatccgt
    12241 atgtgctggc ggaagacaag ctgcaaacct gtcagatgga aattgattta atggcggatg
    12301 tgctgagagc accgccccgt gaatccgcag aactgatccg ctatgtattt gcggatgagt
    12361 ggccggaata aataaaaccg ggcttaatac agattaagcc cgtatcgggt attattactg
    12421 aataccagac agcttacgga ggacggaatg ttacccattg agacaaccag actgccttct
    12481 gattattaat atttttcact attaatcaga aggaataacc atgaatttta cccggattga
    12541 cctgaatacc tggaatcgca gggaacattt tgccctttat cgtcagcaga ttaaatgcgg
    12601 attcagcctg accaccaaac tcgatattac cgctttgcgt actgcactgg cgaaaaccgg
    12661 ttataagttt tatccgctga tgatttacct gatctcccgg gctgttaatc agtttccgga
    12721 gttccggatg gcaatgaaag ataatgaact gatttactgg gaacagtcag acccggtctt
    12781 tactgtcttt cataaagaaa ccgaaacatt ctccgcactg tcctgccgtt attttccgga
    12841 tctcagtgag tttatggcgg gttataacgc ggtaacagca gaatatcagc atgataccag
    12901 gttgtttccg cagggaaatt taccggagaa tcacctgaat atatcatcgt taccctgggt
    12961 gagttttgac ggatttaatc tgaatatcac cggaaatgat gattattttt ccccggtttt
    13021 tacaatggca aagtttcagc aggaaggtga ccgcgtacta ttacctgttt ctgtacaggt
    13081 tcatcatgca gtctgtgatg gttttcatgc agcaaggttt atcaatacac ttcagctgat
    13141 gtgtgataac atactgaaat aaattaatta attctgtatt taagccaccg tatccggcag
    13201 gattggtggc ttttttttat attttaaccg taatctgtaa tttcgtttca gaaggcactg
    13261 ttgcaaagtt agcgatgagg cagccttttg tcttattcaa aggccttaca tttcaaaaac
    13321 tctgcttacc aggcgcattt cgcccagggg atcaccataa taaaatgctg aggcctggcc
    13381 tttgcgtagt gcacgcatca cctcaatacc tttgatggtg gcgtaagccg tcttcatgga
    13441 tttaaatccc agcgtggcgc cgattatccg tttcagtttg ccatgatcgc attcaatcac
    13501 gttgttccgg tacttaatct gtcggtgttc aacgtcagac gggcaccggc cttcgcgttt
    13561 gagcagagca agcgcgcgac cataggcggg cgctttatcc gtgttgatga atcgcgggat
    13621 ctgccacttc ttcacgttgt tgaggatttt acccagaaac cggtatgcag ctttgctgtt
    13681 acgacgggag gagagataaa aatcgacagt gcggccccgg ctgtcgacgg cccggtacag
    13741 atacgcccag cggccattga ccttcacgta ggtttcatcc atgtgccacg ggcaaagatc
    13801 ggaagggtta cgccagtacc agcgcagccg tttttccatt tcaggcgcat aacgctgaac
    13861 ccagcggtaa atcgtggagt gatcgacatt cactccgcgt tcagccagca tctcctgcag
    13921 ctcacggtaa ctgatgccgt atttgcagta ccagcgtacg gcccacagaa tgatgtcacg
    13981 ctgaaaatgc cggcctttga atgggttcat gtgcagctcc atcagcaaaa ggggatgata
    14041 agtttatcac caccgactat ttgcaacagt gccgccagga atgcccggcg cgcggatact
    14101 tccgctcaag ggcgtcggga agcgcaacgc cgctgcggcc ctcggcctgg tccttcagcc
    14161 accatgcccg tgcacgcgac agctgctcgc gcaggctggg tgccaagctc tcgggtaaca
    14221 tcaaggcccg atccttggag cccttgccct cccgcacgat gatcgtgccg tgatcgaaat
    14281 ccagatcctt gacccgcagt tgcaaaccct cactgatccg catgcccgtt ccatacagaa
    14341 gctgggcgaa caaacgatgc tcgccttcca gaaaaccgag gatgcgaacc acttcatccg
    14401 gggtcagcac caccggcaag cgccgcgacg gccgaggtct tccgatctcc tgaagccagg
    14461 gcagatccgt gcacagcacc ttgccgtaga agaacagcaa ggccgccaat gcctgacgat
    14521 gcgtggagac cgaaaccttg cgctcgttcg ccagccagga cagaaatgcc tcgacttcgc
    14581 tgctgcccaa ggttgccggg tgacgcacac cgtggaaacg gatgaaggca cgaacccagt
    14641 ggacataagc ctgttcggtt cgtaaactgt aatgcaagta gcgtatgcgc tcacgcaact
    14701 ggtccagaac cttgaccgaa cgcagcggtg gtaacggcgc agtggcggtt ttcatggctt
    14761 gttatgactg tttttttgta cagtctatgc ctcgggcatc caagcagcaa gcgcgttacg
    14821 ccgtgggtcg atgtttgatg ttatggagca gcaacgatgt tacgcagcag ggcagtcgcc
    14881 ctaaaacaaa gttagatgca ctaagcacat aattgctcac agccaaacta tcaggtcaag
    14941 tctgctttta ttatttttaa gcgtgcataa taagccctac acaaattggg agttagacat
    15001 catgagcaac gcaaaaacaa agttaggcat cacaaagtac agcatcgtga ccaacagcaa
    15061 cgattccgtc acactgcgcc tcatgactga gcatgacctt gcgatgctct atgagtggct
    15121 aaatcgatct catatcgtcg agtggtgggg cggagaagaa gcacgcccga cacttgctga
    15181 cgtacaggaa cagtacttgc caagcgtttt agcgcaagag tccgtcactc catacattgc
    15241 aatgctgaat ggagagccga ttgggtatgc ccagtcgtac gttgctcttg gaagcgggga
    15301 cggacggtgg gaagaagaaa ccgatccagg agtacgcgga atagaccagt tactggcgaa
    15361 tgcatcacaa ctgggcaaag gcttgggaac caagctggtt cgagctctgg ttgagttgct
    15421 gttcaatgat cccgaggtca ccaagatcca aacggacccg tcgccgagca acttgcgagc
    15481 gatccgatgc tacgagaaag cggggtttga gaggcaaggt accgtaacca ccccatatgg
    15541 tccagccgtg tacatggttc aaacacgcca ggcattcgag cgaacacgca gtgatgccta
    15601 acccttccat cgagggggac gtccaagggc tggcgccctt ggccgcccct catgtcaaac
    15661 gttgggcgaa cccggagcct cattaattgt tagccgttaa aattaagccc tttaccaaac
    15721 caatacttat tatgaaaaac acaatacata tcaacttcgc tattttttta ataattgcaa
    15781 atattatcta cagcagcgcc agtgcatcaa cagatatctc tactgttgca tctccattat
    15841 ttgaaggaac tgaaggttgt tttttacttt acgatgcatc cacaaacgct gaaattgctc
    15901 aattcaataa agcaaagtgt gcaacgcaaa tggcaccaga ttcaactttc aagatcgcat
    15961 tatcacttat ggcatttgat gcggaaataa tagatcagaa aaccatattc aaatgggata
    16021 aaacccccaa aggaatggag atctggaaca gcaatcatac accaaagacg tggatgcaat
    16081 tttctgttgt ttgggtttcg caagaaataa cccaaaaaat tggattaaat aaaatcaaga
    16141 attatctcaa agattttgat tatggaaatc aagacttctc tggagataaa gaaagaaaca
    16201 acggattaac agaagcatgg ctcgaaagta gcttaaaaat ttcaccagaa gaacaaattc
    16261 aattcctgcg taaaattatt aatcacaatc tcccagttaa aaactcagcc atagaaaaca
    16321 ccatagagaa catgtatcta caagatctgg ataatagtac aaaactgtat gggaaaactg
    16381 gtgcaggatt cacagcaaat agaaccttac aaaacggatg gtttgaaggg tttattataa
    16441 gcaaatcagg acataaatat gtttttgtgt ccgcacttac aggaaacttg gggtcgaatt
    16501 taacatcaag cataaaagcc aagaaaaatg cgatcaccat tctaaacaca ctaaatttat
    16561 aaaaaatcta atggcaaaat cgcccaaccc ttcaatcaag tcgggacggc caaaagcaag
    16621 cttttggctc ccctcgctgg cgctcggcgc cccttatttc aaacgttaga cggcaaagtc
    16681 acagaccgcg ggatctctta tgaccaacta ctttgatagc cccttcaaag gcaagctgct
    16741 ttctgagcaa gtgaagaacc ccaatatcaa agttgggcgg tacagctatt actctggcta
    16801 ctatcatggg cactcattcg atgactgcgc acggtatctg tttccggacc gtgatgacgt
    16861 tgataagttg atcatcggta gtttctgctc tatcgggagt ggggcttcct ttatcatggc
    16921 tggcaatcag gggcatcggt acgactgggc atcatctttc ccgttctttt atatgcagga
    16981 agaacctgca ttctcaagcg cactcgatgc cttccaaaaa gcaggtaata ctgtcattgg
    17041 caatgacgtt tggatcggct ctgaggcaat ggtcatgccc ggaatcaaga tcgggcacgg
    17101 tgcggtgata ggcagccgct cgttggtgac aaaagatgtg gagccttacg ctatcgttgg
    17161 cggcaatccc gctaagaaga ttaagaaacg cttcaccgat gaggaaattt cattgcttct
    17221 ggagatggag tggtggaatt ggtcactgga gaagatcaaa gcggcaatgc ccatgctgtg
    17281 ctcgtctaat attgttggcc tgcacaagta ttggctcgag tttgccgtct aacaattcaa
    17341 tcaagccgat gccgcttcgc ggcacggctt atttcaggcg ttatgcagcc aaatcccaac
    17401 aattaagggt cttaaaatgg taaaagattg gattcccatc tctcatgata attacaagca
    17461 ggtgcaagga ccgttctatc atggaaccaa agccaatttg gcgattggtg acttgctaac
    17521 cacagggttc atctctcatt tcgaggacgg tcgtattctt aagcacatct acttttcagc
    17581 cttgatggag ccagcagttt ggggagctga acttgctatg tcactgtctg gcctcgaggg
    17641 tcgcggctac atatacatag ttgagccaac aggaccgttc gaagacgatc cgaatcttac
    17701 gaacaaaaga tttcccggta atccaacaca gtcctataga acctgcgaac ccttgagaat
    17761 tgttggcgtt gttgaagact gggaggggca tcctgttgaa ttaataaggg gaatgttgga
    17821 ttcgttggag gacttaaagc gccgtggttt acacgtcatt gaagactagt cctttgcata
    17881 acaaagccat caaaccggac gccagagatt ccgcgcctgt tgcgcatggc ttcgccattt
    17941 tatgcgcaat aggcgcgcca ccctgtcgcc gtttatggcg gcgttagatg cactaagcac
    18001 ataattgctc acagccaaac tatcaggtca agtctgcttt tattattttt aagcgtgcat
    18061 aataagccct acacaaattg ggagatatat catgaaaggc tggctttttc ttgttatcgc
    18121 aatagttggc gaagtaatcg caacatccgc attaaaatct agcgagggct ttactaagct
    18181 tgccccttcc gccgttgtca taatcggtta tggcatcgca ttttattttc tttctctggt
    18241 tctgaaatcc atccctgtcg gtgttgctta tgcagtctgg tcgggactcg gcgtcgtcat
    18301 aattacagcc attgcctggt tgcttcatgg gcaaaagctt gatgcgtggg gctttgtagg
    18361 tatggggctc ataattgctg cctttttgct cgcccgatcc ccatcgtgga agtcgctgcg
    18421 gaggccgacg ccatggtgac ggtgttcggc attctgaatc tcaccgagga ctccttcttc
    18481 gatgagagcc ggcggctaga ccccgccggc gctgtcaccg cggcgatcga aatgctgcga
    18541 gtcggatcag acgtcgtgga tgtcggaccg gccgccagcc atccggacgc gaggcctgta
    18601 tcgccggccg atgagatcag acgtattgcg ccgctcttag acgccctgtc cgatcagatg
    18661 caccgtgttt caatcgacag cttccaaccg gaaacccagc gctatgcgct caagcgcggc
    18721 gtgggctacc tgaacgatat ccaaggattt cctgaccctg cgctctatcc cgatattgct
    18781 gaggcggact gcaggctggt ggttatgcac tcagcgcagc gggatggcat cgccacccgc
    18841 accggtcacc ttcgacccga agacgcgctc gacgagattg tgcggttctt cgaggcgcgg
    18901 gtttccgcct tgcgacggag cggggtcgct gccgaccggc tcatcctcga tccggggatg
    18961 ggatttttct tgagccccgc accggaaaca tcgctgcacg tgctgtcgaa ccttcaaaag
    19021 ctgaagtcgg cgttggggct tccgctattg gtctcggtgt cgcggaaatc cttcttgggc
    19081 gccaccgttg gccttcctgt aaaggatctg ggtccagcga gccttgcggc ggaacttcac
    19141 gcgatcggca atggcgctga ctacgtccgc acccacgcgc ctggagatct gcgaagcgca
    19201 atcaccttct cggaaaccct cgcgaaattt cgcagtcgcg acgccagaga ccgagggtta
    19261 gatcatgcct agcattcacc ttccggccgc ccgctagcgg accctggtca ggttccgcga
    19321 aggtgggcgc agacatgctg ggctcgtcag gatcaaactg cactatgagg cggcggttca
    19381 taccgcgcca ggggagcgaa tggacagcga ggagcctccg aacgttcggg tcgcctgctc
    19441 gggtgatatc gacgaggttg tgcggctgat gcacgacgct gcggcgtgga tgtccgccaa
    19501 gggaacgccc gcctgggacg tcgcgcggat cgaccggaca ttcgcggaga ccttcgtcct
    19561 gagatccgag ctcctagtcg cgagttgcag cgacggcatc gtcggctgtt gcaccttgtc
    19621 ggccgaggat cccgagttct ggcccgacgc cctcaagggg gaggccgcat atctgcacaa
    19681 gctcgcggtg cgacggacac atgcgggccg gggtgtcagc tccgcgctga tcgaggcttg
    19741 ccgccatgcc gcgcgaacgc aggggtgcgc caagctgcgg ctcgactgcc acccgaacct
    19801 gcgtggccta tacgagcggc tcggattcac ccacgtcgac actttcaatc ccggctggga
    19861 tccaaccttc atcgcagaac gcctagaact cgaaatctaa cgtccgttcg ggcatcgagg
    19921 tccatgtcgg ggtgggacgg gcccgtggct tcaagatcac ttgcagtccg accgcgatgt
    19981 cttggttgcg cgagaggttg tcgatatcct ccacttccat catcaaccct ggataatgcc
    20041 gccgccgtca tcgccgccga cgcccgtgcc gggcttttcg ggcctgtcag gcttgctcgg
    20101 ccttcagcct gcctgggcga gatctccggc ggacggatta acggcggagc ttcgccgcct
    20161 ttcgtgcgtg tgaaggccga agatagttct ctcaaaaaca tccgtttatg agagatacca
    20221 aatgtcattt tcagaagacg actgcaccag ttgattgggc gtaatggctg ttgtgcagcc
    20281 agctcctgac agttcaatat cagaagtgat ctgcaccaat ctcgactatg ctcaatactc
    20341 gtgtgggctc tgttgcaaaa atcgtgaagc ttgagcatgc ttggcggaga ttggacggac
    20401 ggaacgatga cggatttcaa gtggcgccat ttccagggtg atgtgatcct gtgggcggtg
    20461 cgctggtatt gtcgctatcc gatcagctat cgcgaccttg aggaaatgct ggcggaacgc
    20521 ggcatttcgg tcgaccatac gacgatctat cgctgggtcc agtgctacgc cccggagatg
    20581 gagaagcggc tgcgctggtt ctggcggcgt ggctttgatc cgagctggcg cctggatgaa
    20641 acctacgtca aggtgcgggg caagtggacc tacctgtacc gggcagtcga caagcggggc
    20701 gacacgatcg atttctacct gtcgccgacc cgcagcgcca aggcagcgaa gcggttcctg
    20761 ggcaaggccc tgcgaggcct gaagcactgg gaaaagcctg ccacgctcaa taccgacaaa
    20821 gcgccgagct atggtgcagc gatcaccgaa ttgaagcgcg aaggaaagct ggaccgggag
    20881 acggcccacc ggcaggtgaa gtatctcaat aacgtgatcg aggccgatca cggaaagctc
    20941 aagatactga tcaagccggt gcgcggtttc aaatcgatcc ccacggccta tgccacgatc
    21001 aagggattcg aagtcatgcg agccctgcgc aaaggacagg ctcgcccctg gtgcctgcag
    21061 cccggcatca ggggcgaggt gcgccttgtg gagagagctt ttggcattgg gccctcggcg
    21121 ctgacggagg ccatgggcat gctcaaccac catttcgcag cagccgcctg atcggcgcag
    21181 agcgacagcc tacctctgac tgccgccaat ctttgcaaca gagccctcaa taacgtgatc
    21241 gaggccgatc acggaaagct caagatactg atcaagccgg tgcgcggttt caaatcgatc
    21301 cccacggcct atgccacgat caagggattc gaagtcatgc gagccctgcg caaaggacag
    21361 gctcgcccct ggtgcctgca gcccggcatc aggggcgagg tgcgccttgt ggagagagct
    21421 tttggcattg ggccctcggc gctgacggag gccatgggca tgctcaacca ccatttcgca
    21481 gcagccgcct gatcggcgca gagcgacagc ctacctctga ctgccgccaa tctttgcaac
    21541 agagcctccg tcgccatgct cacctcgctt tggtgcacac gagtattgag catagtcgag
    21601 attggtgcag atcacttctg atattgaact gtcaggagct ggctgcacaa cagccattac
    21661 gcccaatcaa ctggtgcagt cgtcttctga aaatgacaca tggcatctga catcaagtta
    21721 gggtatgcct caatctgacg gctgcgaacc gccagggaca ggcgctatgt cagattctgt
    21781 cgcggccttg gcgcgtgcct ggaagcgttc atagcaatcc agcccgcaga aatgttcgac
    21841 gtattccgcg ccttccgggg tgaaggcggc atcgagcgga atttctttgc agcatacgca
    21901 gcaggtggtg caactggcag tgttcggggc gtttgcgttc atggtggtac tcctccagat
    21961 tggttgcgaa gctcaaagct gcccactctc ggctggctgg gaagcggtca tgatcttccc
    22021 ttgaaggccc gcagcagccg cgtcacagac aggacaaaca agccggtcag cgtgagggct
    22081 gcaatacccc agtgctcccc gatgaacgcg ccggccgtcg tgccggctag cacaatggcg
    22141 agaatcggca aatggcaggg acaggtgagc acggccagcg cgccccacaa gtagccggtg
    22201 atcggtttgt gcgtctcaga cggcaagtgc tctgggctgt tcatggcaga ctctccgcgt
    22261 gctgtgccgg ttcggttggc atggcggcca gttgcatttc gaggctggcc agggcctcgc
    22321 gccgacgctc gacgagttgc cgcaacacgg caagctgcgc agacgcaccg tcaccgtccg
    22381 cagcatccag cgcccggcac agccgcgcca gtgcgtccag gccgataccc gcttcgaagg
    22441 cagcccgtac aaagcgcagc cgttgcaacg cggtgtcatc gaacaagccg tagccgcccg
    22501 tggtgcacgc gaccggccgt agcaatccgc gcagcaggta gtcgcgcacg atatgcacgc
    22561 tcaccccggc atcaagggcc agccgggaca ctgtgtaggc gctcattgaa cacctccttt
    22621 tcctcatccg gcgcagcacg aaagctgctt cacgtccttg ctgaaggtct gcgccgcgag
    22681 cttcagccct tcgaccatgg tcaggtaggg gaacaattgg tcggccagtt cctgcacggt
    22741 catacggttg cgaatggcga gcaccgccgt ctggatcagt tcacccgctt ccggggccac
    22801 cgcttgcacg ccgatgagcc gtccgctacc ttcctcgatg accagcttga tgaagccgcg
    22861 tgtgtcgaag ttggcaagcg cacgcggcac gttgtccaag gtcaaggtgc gactgtcggt
    22921 ctcgatcccg tcgtgatgtg cttccgcctc gctgtagccc acggtggcga cctgcgggtc
    22981 ggtgaacacc acggccggca ttgcggtcag gtccagggcc gcatcgccgc cagtcatgtt
    23041 gatcgcagca cgggtgccgg ccgctgccgc cacatagacg aactgaggct ggtcggtgca
    23101 gtcgccagcc gcataaatgt gtggcgtact ggtgcgcatg cccttgtcga tgacgatggc
    23161 cccctgcgca ttggcagcga ctcccgccgc ttccaatgcc aggctgcgcg tgttcggtgc
    23221 cctgccagtg gcgaccagca gctggtcggc gcgtatttca ccgtacccgg tggtcagcac
    23281 gaattcgccg tccacatgcg cgacctggct ggcttgcgtg tgttccaata ccttgatccc
    23341 ttcggcacgg aacgcggctg taacggcctc gccgatggcc gggtcttcgc ggaagaacag
    23401 cgtgttgcgt gccaggatcg tcactttgct gcccagccgg gcaaaggctt gcgccagttc
    23461 cagcgccacc acagacgagc cgatcacggc caggcgctcg ggaatggtgt cgctgaccag
    23521 ggcctcggtg gaagtccagt agggtgactc tttcaggccc ggaatcggcg gcacggccgg
    23581 gctggcaccc gtggcgacca ggcagcggtc gaacgccacc acacgctcgc cgccatcgtt
    23641 taaacggacg gcaaggctct ggtcgtcctt gaaacgcgct tcaccatgca gcacggtgat
    23701 ggccgggttg ctgtccagga tgccttcgta cttggcgtgg cgcagctcat cgacgcgcgc
    23761 ctgctgctgg gccagtagtt tgctgcgatc aatcgcaggc acagtcgccg cgatgccact
    23821 gtcgaatggg ctttcacggc gcaaatgggc gatatgggca gcgcggatca tgatcttgga
    23881 cggcacgcag ccgacattga cgcaagtacc gccgatggtg ccgcgctcga tcagcgtgac
    23941 gttcgcacct tgctcgacgg ccttcagcgc cgccgccatc gcggctccgc cgctgccaat
    24001 aacggcgacg tgcagtccgt ccccatcacc accagccttg tcgccaccgc ccagccatcc
    24061 cagcgccttg ccaagcagtc tgccccgcgc tgaagtggat ggggcatcgg cgggtgtggc
    24121 cttgtagccg aggccggcca cagcggcggt cagcgcctct ggcgaggtgc cgggatcggt
    24181 ggcgagttgc gcggagcctt tcgggtagga cacgagcgcc gacagcacgc ccggcacttt
    24241 ctccagggcg tccttgacat gtgtcgcgca cgagtcgcag gtcattccgg tgatattcaa
    24301 atacattgca tcgttccttt tcgtttcggc aactgccaat gcagttagcc gtgtttgggt
    24361 ggtagttcgc agcggcggtt ggccggtgag agcagatccc agatcgacac cccgatcatc
    24421 aaggccagaa cgacatagag gaggttcgcc gtccaccaat tgccaaaaaa caagagcatg
    24481 gccgccagca cgatggctgg gccgaccatc ccgagcaggc tgcggtacca ttgccgatga
    24541 ctcagccagc ccagtgcatt cgccagcaaa gccacgactg cgaacagcgg cagcagcttg
    24601 gagataaaca acccttcgta ttcctgtaga aagccaaggc cgatggccgc gcccaggctg
    24661 gcgatagccg ggaaacaggc agcgcatccc atcgcggaaa caacgctgcc aagcgcgcca
    24721 gccttgtcgg caatgcgtgt aatcagtccc atgatcgccc caggttcggg ttcagtggct
    24781 cactgcttga cgctggacgg atagcccgcg tctccggttg ccttggtcag cttctgcacg
    24841 ctggtcttgg catcatcgaa cgtgacaacc gcttcgcgtg tctcgaaggt cacgtcaatt
    24901 ttgctgacgc cttcgacctt ggaaatcgcc ttcttgacgg tgatcgggca ggtggagcag
    24961 gtcatgcccg gtacggacag cgtgacggtc tgggtggcgg cccacacggg ggcaacaacg
    25021 gcagcgaggg cgagggcggc aaacagtttt ttcatgatga actcctgtga ttaatagaaa
    25081 aatggcatga cgtagggaaa tccgagcgcg accaggacca gcgcggccac gatccagaaa
    25141 atgagcttgt aagtagctcg cacttgggga atcgcgcaga cctcacccgg tttgcaggct
    25201 tgcgccgggc ggtagatgcg ccgccaggcg aaaaacagcg cgaccagcgc tgcgccgatg
    25261 aagatcgggc gatagggttc cagcaccgtc aggttgccga tccatgcccc gctgaacccc
    25321 aaggcgatca aaaccagcgg ccccaggcag caggccgacg caagaatggc ggccagccca
    25381 ccggcgaaga gcgcgccgcg cccgttttgt ggttcagact tttgtggttc agacatacgc
    25441 ttgtcctttc aaatttggtt tggatagctt aagcttactt ccgtagttat gtacggagtc
    25501 aagcgatatg caaattaatt ttgagaatct gaccattggc gtttttgcca aggcggccgg
    25561 ggtcaatgtg gagaccatcc ggttctacca gcgcaagggc ctgctgccgg agccagacaa
    25621 gccctatggc agcattcgcc gctatggcga ggcggatgta acacgagtgc ggttcgtgaa
    25681 atcggcccag cggctgggct ttagcctgga cgaaatcgcc gagctactgc ggctggagga
    25741 tggcacccat tgcgaggaag ccagcggcct ggccgagcac aagctcaagg atgtgcgcga
    25801 gaagatggcc gacttggcac gcatggaggc cgtgctgtct gaactggtgt gcgcctgcca
    25861 tgcgcggaaa gggaacgttt cctgcccgct gattgcgtca ctgcaagacg gaacgaagct
    25921 cgctgcatcg gcgcggggga gtcacggggt gactacgcct tagcgtgctt tattttccga
    25981 attctgagac gacccc
//
