LOCUS       Tn1331                  7996 bp    DNA     linear       29-SEP-2020
DEFINITION  Klebsiella pneumoniae.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Unclassified.
REFERENCE   1  (bases 1 to 7996)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of Tn1331
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7996)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..7996
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
     repeat_region   1..38
                     /gene="IRL_Tn1331"
     CDS             complement(34..3039)
                     /gene="tnpA"
                     /codon_start=1
                     /product="Tn1331 transposase"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSR
                     GDHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTR
                     REHAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILP
                     GATTLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGP
                     VTISGPAFNEAIERWKTLNDFGLHADNLSTLPAVRLKNLARYAGMTSVFNIARMSPQK
                     RMAVLVAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALA
                     SACSYLLKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRV
                     RRFLPHLLNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVIN
                     KEKHITRRGYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRS
                     LGHPTDPQEAIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPD
                     SLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMA
                     EACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGG
                     GEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDS
                     IFVLEGLLEQETGLNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDH
                     DADYGVLNDIARGQSDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLT
                     QAIIEVGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYT
                     DGQEDQLGALGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINML
                     GHYSFTLAELVTKGHLRPLKEASEVENVA"
     misc_recomb     3083..3196
                     /gene="res"
     CDS             3202..3759
                     /gene="tnpR"
                     /codon_start=1
                     /product="Tn1331 resolvase"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTD
                     REGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGD
                     MGQMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTG
                     ATEIAHQLSIARSTVYKILEDERAS"
     repeat_region   3441..3960
                     /gene="DR"
     CDS             3942..4547
                     /gene="aacA4"
                     /codon_start=1
                     /product="Aminoglycoside 6'-acetyltransferase"
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNR
                     SHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGD
                     GWWEEETDPGVRGIDLSLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNL
                     RAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     misc_recomb     4553..4607
                     /gene="attC_aacA4"
     CDS             4617..5405
                     /gene="aadA1"
                     /codon_start=1
                     /product="Aminoglycoside adenylyltransferase"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKP
                     HSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
                     DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPA
                     QYQPVILEARQAYLGQEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_recomb     5407..5461
                     /gene="attC_aadA1"
     CDS             5465..6289
                     /gene="blaOXA-9"
                     /codon_start=1
                     /product="Beta-lactamase OXA-9"
                     /translation="MKKILLLHMLVFVSATLPISSVASDEVETLKCTIIADAITGNTL
                     YETGECARRVSPCSSFKLPLAIMGFDSGILQSPKSPTWELKPEYNPSPRDRTYKQVYP
                     ALWQSDSVVWFSQQLTSRLGVDRFTEYVKKFEYGNQDVSGDSGKHNGLTQSWLMSSLT
                     ISPKEQIQFLLRFVAHKLPVSEAAYDMAYATIPQYQAAEGWAVHGKSGSGWLRDNNGK
                     INESRPQGWFVGWAEKNGRQVVFARLEIGKEKSDIPGGSKAREDILVELPVLMGNK"
     misc_recomb     6308..6376
                     /gene="attC_blaOXA-9"
     repeat_region   6488..7007
                     /gene="DR"
     CDS             6989..7849
                     /gene="blaTEM-1"
                     /codon_start=1
                     /product="Beta-lactamase TEM-1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGY
                     IELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE
                     YSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRL
                     DRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPL
                     LRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIA
                     EIGASLIKHW"
     repeat_region   7959..7996
                     /gene="IRR_Tn1331"
ORIGIN      
        1 ggggtctgac gctcagtgga acgaaaactc acgttaagca acgttttcta cctctgacgc
       61 ctcttttaat ggtctcagat gtcctttggt caccagttct gccagcgtga aggaataatg
      121 gccgagcata ttgatatgtc cgtggcaaag cggggagagg cgtgcgatat cttcatcatt
      181 cagtgtttca ccctgcgccc ggagatgatc cagggctgcc tgcatataaa tagtgttcca
      241 taacacgacg gcgttagtga ccagccccag tgcgcccagt tgatcttcct gaccgtcggt
      301 atatcgtttt cttatctcac ctttttgacc gtgacagatg gctctggcaa cggcatggcg
      361 gctttctccc cgattaagct gggtcagaat gcgccggcgg taatcttcat catcaatata
      421 attaagcaga tacagcgttt tgttgatgcg ccccacttca atgattgcct gagtcagtcc
      481 ggaaggacgt tcacttttca gcaatgaacg gaccagcact gaagcctgta ctttgcccag
      541 cttcagggag ccagcggtcc ggatcatttc gtcccactga aggactattt ttcggggatc
      601 tgattgccct ctggcaatat cattcagcac gccatagtcg gcatcatggt ccattcgcca
      661 gaaaaccgaa gcaccggcat cagccaggcg tggagaaaac tggtatccca gcagccagaa
      721 aaggccaaag acaagttcgc tggcacctgc tgtatcggtc ataatttcgg ttggattcag
      781 cccggtctcc tgttccagaa ggccttccag cacaaagata gagtccctca gcgtccccgg
      841 tataacgatg ccatgaaagc cggaatactg atcggacaca aagttgtacc aggtgatccc
      901 tctgttatta ccaaagtatt tgcggttcgg tccggcattg attgttctga ctggcgtaac
      961 aaagcgcatt ccatctgcag atgccacttc tcctccaccc catatctgtg ccagtggcag
     1021 cgttgcctga aaatcaacca gtctggcatt agcgctggtg atagtttcag cccgcagata
     1081 gttcgctttt gtccagttca gccggtgtcg ggtcagtgca ggaacatttg atctgatcag
     1141 tggttccaga ccgatattgc aggcttcagc catcagcacg gcgctgatgc tgacgggcag
     1201 atcatcaact ctggcactgg cttcactagc atggaaaaac tcatcagcaa atccggtatg
     1261 ggcgttaatt tcgagcagca actccgttaa atccaccgga gggagcagat cactgatcat
     1321 tttgctcagt cgtttcagac tgtccggctc atcaagactg gcgaggggag aaattgtcaa
     1381 ccggggcttc gggccagaaa catcgagttc gacagcctca ttttcgccaa gacgtgcagc
     1441 aacctgtctg taacgactat caagctgatg acccagagat tttattgctt cctgcgggtc
     1501 tgtcgggtgt cccagagaac gataaacctt aatccggttt gcctgccagt cagcaccctg
     1561 tagtaatctt gctcggggat ctccccaccg gttactgccg gtaacgtaga catccctccg
     1621 cctcagacta tcctgcagtt tactgagaaa gcagagcgtg tatcccctgc gggtgatatg
     1681 tttttccttg ttaatcacca gccgtttcca tgaccgactg ataatttccg ttggtgcgtc
     1741 gtcaaaaaac tgccgccgtg agctgaactc ccggctgagg tagtcacagg cattcagagt
     1801 ggtaaccccg gcaggtgcgg atgaaaattt aacggtattc agcagatggg gcaggaaacg
     1861 acgaacgcgc ccgtactgct ccaccatttc ttcatgaaaa ttatcgtctg agggccgggc
     1921 aatttcacgg acaagcgtga tgatttcagc cagcttttgc ctggggatgt agctgaacac
     1981 ctcagcacga atcgattcgt ccggtgtttc ttctttcagc aggtacgaac atgcgctggc
     2041 gagcgccaat gcagatttat ccagatcctt cagcgagcgg agccgttttt tctgcccaat
     2101 ctttctggcg tcacggatga taacggccag catggcgtcc agaacgtcca gtgcatcatc
     2161 cagcgccagc gtttcccatg caaggacaaa ggcaaccaga accgccatcc ttttctgcgg
     2221 tgacatcctg gcaatattga acaccgaagt cataccagca taacgtgcga gatttttcag
     2281 gcgcacagcc gggagtgtac tcaggttgtc agcatgcaag ccaaaatcgt tcagagtttt
     2341 ccagcgttca attgcttcat taaacgccgg accactgatg gtcacagggc cctttttcag
     2401 tgattccagt aaagacaggc ggctgcaatc agttggcccc agcagcatct ccagctgtga
     2461 acgctgttcg gctgacggta tcagtgccag tttgttccac aggcgcaacg tcgccttttc
     2521 ccttacctct gaaatcaacc gagtcagcgt agtggctccg gggagaataa tacgatgttg
     2581 cataagccac cctgtcgcca gatcgaaaag caggccagga cgttcgttgc ttatccagct
     2641 ccgggtatat aaaagacggg taaggcgaaa tgtccagggc caggcaaatt cacgatactg
     2701 atagtgctga cgtatcagcg ctgcatgctc acggcgggta ttttccctct gaccgtattc
     2761 tgcaagaacg gtgatatcac gaatcccgag ctgtctggcg gtaaaatgcc ggacgccgga
     2821 aggaatatga ttcatatcgg tgaggaaggt gcccagaaaa cggacacatc caatttgcag
     2881 ggcaatgccc agacggttgt gatcacctct gctttttccg ataaattcct tgtctgcttc
     2941 atcaaggtga aaatatcgtg ccagctgaag ctcatccggt tcaccggtga atctgccata
     3001 gctttcagtc tgctcagtgg tcagaaagtc aacgggcata taggcctccc tgccttacgg
     3061 gcatttagta acatttttgc aaccgtccga aatgttataa attatcagac atagtaaaac
     3121 ggcttcgttt gagtgtccat taaatcgtca ttttggcata atagacacat cgtgtctgat
     3181 attcgattta aggtacattt tatgcgaatt tttggttatg cgcgggtctc aaccagccag
     3241 cagtccctcg atattcagat cagagcgctc aaagatgcag gggtaaaagc taaccgcatc
     3301 tttaccgaca aggcatccgg cagttcaaca gatcgggaag ggctggattt gctgaggatg
     3361 aaggtggagg aaggtgatgt cattctggtg aagaagctcg accgtcttgg ccgcgacacc
     3421 gccgacatga tccaactgat aaaagagttt gatgctcagg gtgtcgcggt tcggtttatt
     3481 gacgacggga tcagtaccga cggtgatatg gggcaaatgg tggtcaccat cctgtcggct
     3541 gtggcacagg ctgaacgccg gaggatccta gagcgcacga atgagggccg acaggaagca
     3601 aagctgaaag gaatcaaatt tggccgcagg cgtaccgtgg acaggaacgt cgtgctgacg
     3661 cttcatcaga agggcactgg tgcaacggaa attgctcatc agctcagtat tgcccgctcc
     3721 acggtttata aaattcttga agacgaaagg gcctcgtgat acgcctattt ttataggtta
     3781 atgtcatgat aataatggtt tcttagacgt caggtggcac ttttcgggga aatgtgcgcg
     3841 gaacccctat ttgtttattt ttctaaatac attcaaatat gtatccgctc atgagacaat
     3901 aaccctgata aatgcttcaa taatattgaa aaaggaagag tatgagtatt caacatttcc
     3961 aaacaaagtt aggcatcaca aagtacagca tcgtgaccaa cagcaacgat tccgtcacac
     4021 tgcgcctcat gactgagcat gaccttgcga tgctctatga gtggctaaat cgatctcata
     4081 tcgtcgagtg gtggggcgga gaagaagcac gcccgacact tgctgacgta caggaacagt
     4141 acttgccaag cgttttagcg caagagtccg tcactccata cattgcaatg ctgaatggag
     4201 agccgattgg gtatgcccag tcgtacgttg ctcttggaag cggggacgga tggtgggaag
     4261 aagaaaccga tccaggagta cgcggaatag acctgtcact ggcgaatgca tcacaactgg
     4321 gcaaaggctt gggaaccaag ctggttcgag ctctggttga gttgctgttc aatgatcccg
     4381 aggtcaccaa gatccaaacg gacccgtcgc cgagcaactt gcgagcgatc cgatgctacg
     4441 agaaagcggg gtttgagagg caaggtaccg taaccacccc agatggtcca gccgtgtaca
     4501 tggttcaaac acgccaggca ttcgagcgaa cacgcagtgt tgcctaaccc ttccatcgag
     4561 ggggacgtcc aagggctggc gcccttggcc gcccctcatg tcaaacgtta aacatcatga
     4621 gggaagcggt gatcgccgaa gtatcgactc aactatcaga ggtagttggc gtcatcgagc
     4681 gccatctcga accgacgttg ctggccgtac atttgtacgg ctccgcagtg gatggcggcc
     4741 tgaagccaca cagtgatatt gatttgctgg ttacggtgac cgtaaggctt gatgaaacaa
     4801 cgcggcgagc tttgatcaac gaccttttgg aaacttcggc ttcccctgga gagagcgaga
     4861 ttctccgcgc tgtagaagtc accattgttg tgcacgacga catcattccg tggcgttatc
     4921 cagctaagcg cgaactgcaa tttggagaat ggcagcgcaa tgacattctt gcaggtatct
     4981 tcgagccagc cacgatcgac attgatctgg ctatcttgct gacaaaagca agagaacata
     5041 gcgttgcctt ggtaggtcca gcggcggagg aactctttga tccggttcct gaacaggatc
     5101 tatttgaggc gctaaatgaa accttaacgc tatggaactc gccgcccgac tgggctggcg
     5161 atgagcgaaa tgtagtgctt acgttgtccc gcatttggta cagcgcagta accggcaaaa
     5221 tcgcgccgaa ggatgtcgct gccgactggg caatggagcg cctgccggcc cagtatcagc
     5281 ccgtcatact tgaagctagg caggcttatc ttggacaaga agatcgcttg gcctcgcgcg
     5341 cagatcagtt ggaagaattt gttcactacg tgaaaggcga gatcaccaag gtagtcggca
     5401 aataatgtct aaaacaaagt tatgcaccta ttaagcgcac agcggagcaa tgaaggatac
     5461 cttgatgaaa aaaattttgc tgctgcatat gttggtgttc gtttccgcca ctctcccaat
     5521 cagttccgtg gcttctgatg aggttgaaac gcttaaatgc accatcatcg cagacgccat
     5581 taccggaaat accttatatg agaccggaga atgtgcccgt cgtgtgtctc cgtgctcgtc
     5641 ttttaaactt ccattggcaa tcatggggtt tgatagtgga atcttgcagt cgccaaaatc
     5701 acctacgtgg gaattgaagc cggaatacaa cccgtctccg agagatcgca catacaaaca
     5761 agtctatccg gcgctatggc aaagcgactc tgttgtctgg ttctcgcagc aattaacaag
     5821 ccgtctggga gttgatcggt tcacggaata cgtaaagaaa tttgagtacg gtaatcaaga
     5881 tgtttccggt gactcgggga agcataacgg cttgacccag tcatggctga tgtcgtcgct
     5941 caccatatct cccaaggagc aaattcagtt tcttctacgc tttgtcgcgc ataagctgcc
     6001 tgtatccgaa gcggcttatg acatggcgta tgccacaatc ccgcagtacc aggcagccga
     6061 aggatgggct gtacatggaa aaagcggcag cggctggctt cgggacaata acggcaagat
     6121 aaatgaaagt cgtccgcagg gctggttcgt gggctgggct gaaaaaaacg gacggcaagt
     6181 tgttttcgcc cgattggaaa taggaaagga aaagtccgat attcccggcg ggtctaaagc
     6241 acgagaggat attctcgtgg aattacccgt gttgatgggt aacaaatgat atgtggcgtc
     6301 atcgagagca gatgcataac cctgcgctcg agcggacctc gcgcataaag ccgcgcgagt
     6361 ccgctcacct tgaacgttag atgcactaag cacataattg ctcacagcca aactatcagg
     6421 tcaagtctgc ttttattatt tttaagcgtg cataataagc cctacacaaa ttgggagata
     6481 tatcatgaaa agagtttgat gctcagggtg tagcggttcg gtttattgac gacgggatca
     6541 gtaccgacgg tgatatgggg caaatggtgg tcaccatcct gtcggctgtg gcacaggctg
     6601 aacgccggag gatcctagag cgcacgaatg agggccgaca ggaagcaaag ctgaaaggaa
     6661 tcaaatttgg ccgcaggcgt accgtggaca ggaacgtcgt gctgacgctt catcagaagg
     6721 gcactggtgc aacggaaatt gctcatcagc tcagtattgc ccgctccacg gtttataaaa
     6781 ttcttgaaga cgaaagggcc tcgtgatacg cctattttta taggttaatg tcatgataat
     6841 aatggtttct tagacgtcag gtggcacttt tcggggaaat gtgcgcggaa cccctatttg
     6901 tttatttttc taaatacatt caaatatgta tccgctcatg agacaataac cctgataaat
     6961 gcttcaataa tattgaaaaa ggaagagtat gagtattcaa catttccgtg tcgcccttat
     7021 tccctttttt gcggcatttt gccttcctgt ttttgctcac ccagaaacgc tggtgaaagt
     7081 aaaagatgct gaagatcagt tgggtgcacg agtgggttac atcgagctgg atctcaacag
     7141 cggtaagatc cttgagagtt ttcgccccga agaacgtttt ccaatgatga gcacttttaa
     7201 agttctgcta tgtggtgcgg tattatcccg tgttgacgcc gggcaagagc aactcggtcg
     7261 ccgcatacac tattctcaga atgacttggt tgagtactca ccagtcacag aaaagcatct
     7321 tacggatggc atgacagtaa gagaattatg cagtgctgcc ataaccatga gtgataacac
     7381 tgctgccaac ttacttctga caacgatcgg aggaccgaag gagctaaccg cttttttgca
     7441 caacatgggg gatcatgtaa cccgccttga tcgttgggaa ccggagctga atgaagccat
     7501 accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt tgcgcaaact
     7561 attaactggc gaactactta ctctagcttc ccggcaacaa ttaatagact ggatggaggc
     7621 ggataaagtt gcaggaccac ttctgcgctc ggcccttccg gctggctggt ttattgctga
     7681 taaatctgga gccggtgagc gtggatctcg cggtatcatt gcagcactgg ggccagatgg
     7741 taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta tggatgaacg
     7801 aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca
     7861 agtttactca tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta
     7921 ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca
     7981 ctgagcgtca gacccc
//
