LOCUS       In469                  21237 bp    DNA     linear       22-OCT-2020
DEFINITION  Providencia rettgeri.
ACCESSION
VERSION
KEYWORDS    .
SOURCE      Providencia rettgeri
  ORGANISM  Providencia rettgeri
            Unclassified.
REFERENCE   1  (bases 1 to 21237)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of In469
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21237)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-OCT-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: newbler v. 2.6
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..21237
                     /organism="Providencia rettgeri"
                     /mol_type="genomic DNA"
     mobile_element  1..21237
                     /gene="In469"
                     /product="Complex class 1 integron: In469"
     repeat_region   1..25
                     /gene="IRi_In469"
                     /product="Inverted repeat at the integrase end of In469"
     CDS             complement(203..1216)
                     /gene="intI1"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     regulatory      1101..1129
                     /gene="PcWTGN-10"
                     /product="Promoter PcWTGN-10"
     regulatory      1101..1106
                     /gene="-35 region_PcWTGN-10"
                     /product="-35 region of PcWTGN-10"
     regulatory      1121..1122
                     /gene="extended_-10"
                     /product="Extended -10 region"
     regulatory      1124..1129
                     /gene="-10 region_PcWTGN-10"
                     /product="-10 region of PcWTGN-10"
     misc_recomb     1297..1359
                     /gene="attI1"
                     /product="attI1 site"
     CDS             1389..1841
                     /gene="arr3"
                     /codon_start=1
                     /transl_table=11
                     /product="Rifampin ADP-ribosylating transferase"
                     /translation="MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFED
                     GRILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGN
                     PTQSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED"
     misc_recomb     1848..1961
                     /gene="attC_arr3"
                     /product="attC site for arr3"
     CDS             1974..2447
                     /gene="dfrA27"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydrofolate reductase"
                     /translation="MKISLMAAKARNGVIGCGSDIPWNAKGEQLLFKAITYNQWLLVG
                     RKTFEAMGALPNRKYAVVSRSGSVATNDDVVVFPSIEAAMRELKTLTNHVVVSGGGEI
                     YKSLIAHADTLHISTIDSEPEGNVFFPEIPKEFNVVFEQEFHSNINYRYQIWQRG"
     misc_recomb     2442..2523
                     /gene="attC_dfrA27"
                     /product="attC site for dfrA27"
     CDS             2628..3473
                     /gene="aadA16"
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside 3'-adenyltransferase"
                     /translation="MSNAVPAEISVQLSQALNVIEHHLGSTLLAVHLYGSALDGGLKP
                     CSDIDLLVTVTAQLDETVRQALFVDFLEVSASPGQSEALRALEVTIVVYGDVVPWRYP
                     ARRELQFGEWQRKDILAGIFEPATTDVDLAILLTKARQHSLALAGSAAEDFFNSVPES
                     DLFKALADTLKLWNSQPDWAGDERNVVLTLSRIWYSAATGKIAPKDVAANWVMERLPV
                     QHQPVLLEAQQAYLGQGMDCLASRADQLTAFIYFVKHEAASLLGSTPMMSNSSFKPTP
                     LRGAA"
     misc_recomb     3428..3487
                     /gene="attC_aadA16"
                     /product="attC site for aadA16"
     CDS             3590..3937
                     /gene="qacED1"
                     /codon_start=1
                     /transl_table=11
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             3931..4770
                     /gene="sul1"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     mobile_element  complement(4795..6948)
                     /gene="ISCR1"
                     /product="Insertion sequence: ISCR1"
     CDS             5175..6716
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     repeat_region   6928..6948
                     /gene="oriIS"
                     /product="ISCR1 oriIS"
     mobile_element  complement(6949..6976)
                     /gene="truncated ISCR1"
                     /product="Insertion sequence: truncated ISCR1"
     repeat_region   complement(6956..6976)
                     /gene="oriIS"
                     /product="ISCR1 oriIS"
     CDS             7039..7965
                     /gene="blaPER-1"
                     /codon_start=1
                     /transl_table=11
                     /product="Beta-lactamase PER-1"
                     /translation="MNVIIKAVVTASTLLMVSFSSFETSAQSPLLKEQIESIVIGKKA
                     TVGVAVWGPDDLEPLLINPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAK
                     VLQNTWAPIMKAYQGDEFSVPVQQLLQYSVSHSDNVACDLLFELVGGPAALHDYIQSM
                     GIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQALLWKWMVE
                     TTTGPERLKGLLPAGTVVAHKTGTSGIKAGKTAATNDLGIILLPDGRPLLVAVFVKDS
                     AESSRTNEAIIAQVAQTAYQFELKKLSALSPN"
     CDS             8039..8614
                     /codon_start=1
                     /transl_table=11
                     /product="Maleylacetoacetate isomerase / Glutathione
                     S-transferase"
                     /translation="MQLLGSVASPFVRRLRLVLAGQPYQFVALNIFESEGRSVLVQHN
                     PARKVPVLVDGEQVIFDSGVIYRYLASKLKFKPLSWDQENGLTTINACTDSLVELLLC
                     KRSGFDVTEDKLFFNLQHERIQATLEALEQQIRAGHFGDWDYPGISLFTLIDWILFRD
                     LVDLKPFPVLLQFRNAHLNRPMVAETDPRLS"
     CDS             complement(8653..10494)
                     /gene="mdlB"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC MDR transporter/ATP-binding cassette (ABC)
                     transporters"
                     /translation="MLGFFERLTNPFPDKEPTQPPQGLFAFCLHYSQGMVLPLILMSI
                     ATALLAALEVSLFGYMGQLVDWLVTKNPATFWQEEQDTLITMAIVMLLVLPGLVFFHS
                     ALIHQTILGNYPMSIRWLAHRYLLKQSLGFYQNEFAGRIATKVMQTALAVRETATKLL
                     DVMVYVVVYFGSMLYLIADADWRLVLPMIAWLVIYTGLQFYFVPRLKQVATEQADARS
                     EMTGRIVDSYTNISTIKLFSHTARESEYARDSMQLFLVPVYRQMRLATWLNICVQGLN
                     YLLVFSIATLAIWLWSVNAVTVGSIAIAVSLALRLNGMSQWIMWEVSALFENIGTVAD
                     GIATLSQPQQIIDKADAKPLEVPQGQIEFKQLNFNYGKAAGEHGPVIDGLDLSIKPGE
                     KVGLVGRSGAGKSTLVNLLLRFYDVNSGQILIDGQDIKTVSQESLRAHIAMVTQDTSL
                     LHRTVRENILYGRPGATEAEMIEAARLAEADAFIQELTDPKGNSGYDAQVGERGVKLS
                     GGQRQRIAIARVLLKNAPILILDEATSALDSEVESAIQHSLTQLMIGKTVIAIAHRLS
                     TIAAMDRLIVLDQGRIVEQGSHQELIAKGGIYAQLWAHQTGGFIGVE"
     CDS             10865..11566
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MDAKELLVYMKQAELQAELVVEAGQQLDRAIKQLHDWSEDWDCQ
                     RRACEDMYDAVHLILIHSYQLSRIFWPAKCCGELGLDLCHRAMALRSEINLPDLNHPL
                     RNEALWRHADELDHSVRDNTALRRYQAHHLTGFNQVITWMDNEAMFCWLEPASKTFVF
                     HAEEFALAQLLDAVHQVQQDIQNFLNKQHQSNLKVAKAGVHHYEKQWGAFKIRQDRSC
                     PQLCCYDYLSNLINP"
     CDS             complement(11539..11868)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MLTFVMSAITFGFLLLSLFFYKKLIGMSDALNIIEKQVAADMEI
                     RAHRLCLLAYEAQRFGNSVDRRALDEEFKDFLHLYIEDYQAEVAKKIREHKLSEISAY
                     GFIKLDK"
     CDS             complement(12367..12597)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MQINLNTPGTAATSTIQTVAPAAQAKTTTTTAPSTADTVTLSAE
                     AKAKLAAEQQESKAINPTLTTLGGGWGNEPPK"
     misc_feature    12633..12917
                     /gene="truncated qacED1"
                     /product="Truncated quaternary ammonium compound
                     resistance protein (pseudogene)"
     CDS             12911..13750
                     /gene="sul1"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     mobile_element  complement(13775..15928)
                     /gene="ISCR1"
                     /product="Insertion sequence: ISCR1"
     CDS             14155..15696
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     repeat_region   15908..15928
                     /gene="oriIS"
                     /product="ISCR1 oriIS"
     misc_feature    15929..16341
                     /product="Truncated Enoyl-CoA hydratase (pseudogene)"
     CDS             16587..17366
                     /gene="aphA6"
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside O-phosphotransferase"
                     /translation="MELPNIIQQFIGNSVLEPNKIGQSPSDVYSFNRNNETFFLKRSS
                     TLYTETTYSVSREAKMMSWLSDKLKVPELIMTFQDEQFEFMITKAINAKPISALFLTE
                     QELLSIYKETLNQLNAVAIFDCPFISSIDHRLKESKFFIDNQLLDEIDQDDFEAELWG
                     DHKTYLSLWNELNETRVEERLVFSHGDITDSNIFIDKSGEIYFLDLGRAGLADEFVDI
                     SFVERCLREDVSEETAKIFLKHLKNDMPDKRNYFLKLDELN"
     mobile_element  complement(17813..18360)
                     /gene="truncated ISAba14"
                     /product="Insertion sequence: truncated ISAba14"
     repeat_region   complement(17813..17866)
                     /gene="IRR_ISAba14"
                     /product="ISAba14 inverted repeat right"
     misc_feature    complement(17874..18360)
                     /gene="truncated orf2"
                     /product="Truncated ISAba14 transposase Orf2 (pseudogene)"
     misc_feature    18357..18733
                     /product="Efflux transporter outer membrane factor
                     lipoprotein (pseudogene)"
     CDS             18702..18917
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MAVTGIPKRINYWLNKILSKVKQLAITVSCFFVCRISVQTQREQ
                     ELQRLQAELRLAQQALSVKQQEVVTGS"
     mobile_element  19000..19278
                     /gene="truncated ISSod18"
                     /product="Insertion sequence: truncated ISSod18"
     repeat_region   19000..19036
                     /gene="IRL_ISSod18"
                     /product="ISSod18 inverted repeat left"
     misc_feature    19060..19278
                     /gene="truncated tnpA"
                     /product="Truncated ISSod18 transposase (pseudogene)"
     mobile_element  complement(19279..20603)
                     /gene="ISEc29"
                     /product="Insertion sequence: ISEc29"
     repeat_region   complement(19279..19299)
                     /gene="IRR_ISEc29"
                     /product="ISEc29 inverted repeat right"
     CDS             complement(19313..20497)
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISEc29 transposase"
                     /translation="MLTMNVKAMLADFLTFVTPKSMHKARFSVLLDAVTALAKDACCT
                     VTAIGRAMPGSSDKVSIKRADRLLNNPNLQRELPLIYAALTASIVGHKTKPMILVDWS
                     NADTAKRHFILRASIAADGRALTLLQKIAAAEDYTCPHLHGAFLKQLKAMLPKDCKPV
                     IVTDAGFKVPWLKQVRKLGWHYVARVRGNVKLKLAEQDKFISVNQLYRQAKKDPKSVG
                     KIMLAQTQHYETQAVLVGKGYKLLKRDKNKTYKEPWLLVSSLADCHGYADKIAKCYSS
                     RMQIEESFRDQKSHRYGLGSDLHGTKKKSRLEILLLLAALVNWFHYLLGSAAEKAGLH
                     LRYQANTVKNRRVLALNFLGILLCKEPKQRIRRQYYQQGLKQILQWVVQWDWAVIKQA
                     DS"
     repeat_region   complement(20583..20603)
                     /gene="IRL_ISEc29"
                     /product="ISEc29 inverted repeat left"
     misc_feature    complement(20604..21237)
                     /gene="truncated repAciN"
                     /product="Truncated plasmid replication protein RepA"
BASE COUNT     5537 a   5182 c   5040 g   5478 t
ORIGIN
        1 tgtcgttttc agaagacggc tgcactgaac gtcagaagcc gactgcacta tagcagcgga
       61 ggggttggat ccatcaggca acgacgggct gctgccggcc atcagcggac gcagggagga
      121 ctttccgcaa ccggccgttc gatgcggcac cgatggcctt cgcgcagggg tagtgaatcc
      181 gccaggattg acttgcgctg ccctacctct cactagtgag gggcggcagc gcatcaagcg
      241 gtgagcgcac tccggcaccg ccaactttca gcacatgcgt gtaaatcatc gtcgtagaga
      301 cgtcggaatg gccgagcaga tcctgcacgg ttcgaatgtc gtaaccgctg cggagcaagg
      361 ccgtcgcgaa cgagtggcgg agggtgtgcg gtgtggcggg cttcgtgatg cctgcttgtt
      421 ctacggcacg tttgaaggcg cgctgaaagg tctggtcata catgtgatgg cgacgcacga
      481 caccgctccg tggatcggtc gaatgcgtgt gctgcgcaaa aacccagaac cacggccagg
      541 aatgcccggc gcgcggatac ttccgctcaa gggcgtcggg aagcgcaacg ccgctgcggc
      601 cctcggcctg gtccttcagc caccatgccc gtgcacgcga cagctgctcg cgcaggctgg
      661 gtgccaagct ctcgggtaac atcaaggccc gatccttgga gcccttgccc tcccgcacga
      721 tgatcgtgcc gtgatcgaaa tccagatcct tgacccgcag ttgcaaaccc tcactgatcc
      781 gcatgcccgt tccatacaga agctgggcga acaaacgatg ctcgccttcc agaaaaccga
      841 ggatgcgaac cacttcatcc ggggtcagca ccaccggcaa gcgccgcgac ggccgaggtc
      901 ttccgatctc ctgaagccag ggcagatccg tgcacagcac cttgccgtag aagaacagca
      961 aggccgccaa tgcctgacga tgcgtggaga ccgaaacctt gcgctcgttc gccagccagg
     1021 acagaaatgc ctcgacttcg ctgctgccca aggttgccgg gtgacgcaca ccgtggaaac
     1081 ggatgaaggc acgaacccag tggacataag cctgttcggt tggtaagctg taatgcaagt
     1141 agcgtatgcg ctcacgcaac tggtccagaa ccttgaccga acgcagcggt ggtaacggcg
     1201 cagtggcggt tttcatggct tgttatgact gtttttttgt acagtctatg cctcgggcat
     1261 ccaagcagca agcgcgttac gccgtgggtc gatgtttgat gttatggagc agcaacgatg
     1321 ttacgcagca gggcagtcgc cctaaaacaa agttatgcag ccaaatccca acaattaagg
     1381 gtcttaaaat ggtaaaagat tggattccca tctctcatga taattacaag caggtgcaag
     1441 gaccgttcta tcatggaacc aaagccaatt tggcgattgg tgacttgcta accacagggt
     1501 tcatctctca tttcgaggac ggtcgtattc ttaagcacat ctacttttca gccttgatgg
     1561 agccagcagt ttggggagct gaacttgcta tgtcactgtc tggcctcgag ggtcgcggct
     1621 acatatacat agttgagcca acaggaccgt tcgaagacga tccgaatctt acgaacaaaa
     1681 gatttcccgg taatccaaca cagtcctata gaacctgcga acccttgaga attgttggcg
     1741 ttgttgaaga ctgggagggg catcctgttg aattaataag gggaatgttg gattcgttgg
     1801 aggacttaaa gcgccgtggt ttacacgtca ttgaagacta gtcctttgca taacaaagcc
     1861 atcaaaccgg acgccagaga ttccgcgcct gttgcgcatg gcttcgccat tttatgcgca
     1921 ataggcgcgc caccctgtcg ccgtttatgg cggcgttaac ccaaaggagt atcgtgaaaa
     1981 tatcactaat ggctgcaaaa gcaagaaatg gggttattgg ctgcggctcg gatatcccgt
     2041 ggaacgctaa aggtgagcag ctgcttttta aagcaataac ttacaatcaa tggctcttag
     2101 tcggccgtaa aacatttgag gcaatggggg ctctcccaaa tagaaagtat gcagttgtca
     2161 gccgctcagg atcggtagct actaacgatg atgtggttgt gtttccatct atagaagcag
     2221 caatgaggga gctaaagact cttacgaacc atgttgttgt ttctggtggt ggagagatct
     2281 acaagagtct gatcgcccat gccgacacgc tacatatctc gacaatagat tccgagccag
     2341 agggcaatgt tttctttccg gaaatcccca aagagttcaa tgtggtgttc gagcaggaat
     2401 ttcattcaaa tataaattat cgctatcaaa tctggcaaag gggttaacca tccaagccat
     2461 cggacacatt ttgcttcgct gcgctcaaaa cgcaaaatgt gccgctgctt agcggcgtta
     2521 gatgcactaa gcacataatt gctcacagcc aaactatcag gtcaagtctg cttttattat
     2581 ttttaagcgt gcataataag ccctacacaa attgggagtt agacatcatg agcaacgcag
     2641 tgcccgccga gatttcggta cagctatcac aggcactcaa cgtcatcgag catcatctgg
     2701 gatcgacgtt gctggccgtg catttgtacg gctctgcact cgacggtggc ctgaagccat
     2761 gcagtgatat tgatttgctg gttactgtga ctgcacagct cgatgagact gtgcggcagg
     2821 ctctgttcgt agatttcctg gaagtttccg cttctcccgg ccaaagtgaa gctctccgtg
     2881 ccttggaagt taccatcgtc gtgtacggcg atgttgttcc ttggcgttat ccagccagac
     2941 gggaactgca attcggggag tggcagcgca aggacattct tgcgggcatc ttcgagcccg
     3001 cgacaaccga tgttgatctg gctattctgc taactaaagc aaggcaacac agccttgcct
     3061 tggcaggttc ggccgcggaa gatttcttca actcagtccc ggaaagcgat ctattcaaag
     3121 cactggccga caccttgaaa ctatggaact cacaaccgga ttgggcaggc gacgagcgga
     3181 atgtagtgct tactttgtct cgcatttggt acagcgcagc aaccggcaag atcgcgccga
     3241 aggatgtagc tgccaactgg gtaatggaac gcctgcccgt ccaacatcag cccgtgctgc
     3301 ttgaagccca gcaggcttac cttggacaag ggatggattg cttggcctca cgcgctgatc
     3361 agttgactgc gttcatttac tttgtgaagc acgaagccgc cagtctgctc ggctccacgc
     3421 caatgatgtc taacagttca ttcaagccga cgccgcttcg cggcgcagct taattcaggc
     3481 gttagatgca ctaagcacat aattgctcac agccaaacta tcaggtcaag tctgctttta
     3541 ttatttttaa gcgtgcataa taagccctac acaaattggg agatatatca tgaaaggctg
     3601 gctttttctt gttatcgcaa tagttggcga agtaatcgca acatccgcat taaaatctag
     3661 cgagggcttt actaagcttg ccccttccgc cgttgtcata atcggttatg gcatcgcatt
     3721 ttattttctt tctctggttc tgaaatccat ccctgtcggt gttgcttatg cagtctggtc
     3781 gggactcggc gtcgtcataa ttacagccat tgcctggttg cttcatgggc aaaagcttga
     3841 tgcgtggggc tttgtaggta tggggctcat aattgctgcc tttttgctcg cccgatcccc
     3901 atcgtggaag tcgctgcgga ggccgacgcc atggtgacgg tgttcggcat tctgaatctc
     3961 accgaggact ccttcttcga tgagagccgg cggctagacc ccgccggcgc tgtcaccgcg
     4021 gcgatcgaaa tgctgcgagt cggatcagac gtcgtggatg tcggaccggc cgccagccat
     4081 ccggacgcga ggcctgtatc gccggccgat gagatcagac gtattgcgcc gctcttagac
     4141 gccctgtccg atcagatgca ccgtgtttca atcgacagct tccaaccgga aacccagcgc
     4201 tatgcgctca agcgcggcgt gggctacctg aacgatatcc aaggatttcc tgaccctgcg
     4261 ctctatcccg atattgctga ggcggactgc aggctggtgg ttatgcactc agcgcagcgg
     4321 gatggcatcg ccacccgcac cggtcacctt cgacccgaag acgcgctcga cgagattgtg
     4381 cggttcttcg aggcgcgggt ttccgccttg cgacggagcg gggtcgctgc cgaccggctc
     4441 atcctcgatc cggggatggg atttttcttg agccccgcac cggaaacatc gctgcacgtg
     4501 ctgtcgaacc ttcaaaagct gaagtcggcg ttggggcttc cgctattggt ctcggtgtcg
     4561 cggaaatcct tcttgggcgc caccgttggc cttcctgtaa aggatctggg tccagcgagc
     4621 cttgcggcgg aacttcacgc gatcggcaat ggcgctgact acgtccgcac ccacgcgcct
     4681 ggagatctgc gaagcgcaat caccttctcg gaaaccctcg cgaaatttcg cagtcgcgac
     4741 gccagagacc gagggttaga tcatgcctag cattcacctt ccggccgccc gctaaatatc
     4801 tccttttggg ttgttaataa aacatccaat aagttgactg tgcgtgaaaa agaaagtttt
     4861 gtgtgatggc gttgaagatc gcaccgttaa gctcttatgt gggatggtgc agagctcgac
     4921 gactaccgat aaaacgcaac cgccgcaaac agacaagaaa aagccccaac tgataacagt
     4981 tggggcttca gtattgtgat tggtggagca atagcaccct gaacccaaaa ccttctcgct
     5041 caaccggtag tggctgataa caactcgtga gggctattgc gggttaagca tttagcgatg
     5101 tctagggcca gactggacgt ctgaacgcaa gccgctgata ctgtacataa ccacagtatc
     5161 agcggaggat acccatgtcg ctggcaagga acgccacggc gagtcaatcg cccactcaaa
     5221 caaacggtta cgaacgccac caacccgacc agacgctgct ctaccagctg gttgagcagc
     5281 actacccagc cttcaaagcc tcactcgaag cccaaggtca acacctgcct cgctacatcc
     5341 aacaagaatt caacgacctc ctccaatgtg gccgtctgga gtatggtttc atgcgggttc
     5401 gctgcgagga ttgtcatcac gagcgtctgg tcgccttcag ctgtaaacga cgcggctttt
     5461 gccctagctg cggtgcccgc cggatggccg agagtgcggc gctgctgata gacgaagtct
     5521 tccccaagga gcccattcgc cagtgggtgc tcagctttcc tttccagcta cgctttttgc
     5581 tggctcgcca tccccagctg atgggccagg tcttgagtat cgtctatcgt acactctcaa
     5641 ctcatctgat caaaaaagcc ggttacacca aagcctctgc acaaactggc tcagtgactc
     5701 ttatccaacg ctttggctcc gcgctaaatc tcaatgtcca ctaccacatg ctgtttctcg
     5761 atggtgtcta tgccgaagat gactatggca agcaacgctt ccatcgtgtc aaggcaccca
     5821 cttacgatga gctgaatacg ctcgctcaca ccctcagcca tcgcatcgct cgctgcatgg
     5881 aaaagcgtgg gattttggag cgtgatgccg agaatacgtg gttgacactg gaagagggcg
     5941 aagacgatac gctgactcaa ttacatggtg cttcggttac gtatcgcatt gccgtcggcc
     6001 cccagcaagg gcgcaaagtc ttcaccctgc aaaccttgcc agggcgtgag gataaagccg
     6061 actcaagcag tcgagtagcc aaccatgctg gtttctcgct acacgccggt gtgatggccg
     6121 aagcgcatca gcgggataag cttgagcgct tgtgtcgcta cattagtcgg ccagcggttt
     6181 cagaaaaacg tctggcatta accgccaatg ggcaggtgcg ttacgagctc aaaactccgt
     6241 accgcaatgg caccacccat gtgatcttcg agccgctgga cttcatcgcc aaactcgctg
     6301 cgttggtacc taagccgcga gtcaacctca cacgcttcca cggcgtcttt gcaccgaaca
     6361 gcaaacaccg agttcaagta acacccgcca agcggggcaa gaagcccgac aaatcggaag
     6421 gtctcgatac taactggcgt gacaagagtc ctgcagagcg ccaccgcgcc atgacctgga
     6481 tgcaacgcct caagcgagtc ttcaatattg atattgaagt ctgcgaacac tgcggcggtc
     6541 acgtcaaagt gattgccagc atcgaagatc cgaaggtcat tgagcagatt ctcaagcatc
     6601 tgaaacagaa aacagccaag gcgaatgccg ccaagcagcg tgagctgcca ccagaacgag
     6661 cgccgccact gactcccagc ctgttcgatc catcacagag tcgtctcttt gactgacgac
     6721 cccaaatcca acactgctca acactgccaa cttttaaacg gggcggtggg gcagtttgta
     6781 tctctcgagc tatcaggcta gagattttac cgccaaatcg aaccttatta gagcggttta
     6841 ggctggaccg gcagttaaaa ttggggcttg agcggtaaac gagtgaggga atttcaggta
     6901 agatacttcg gatgaggagc aaaaaggtgg tttatacttc ctatacccaa aaaggtggtt
     6961 tatacttcct ataccctaaa aaggcagctt tggctgcctt ttgtataatt catatcgact
     7021 tatcaaaagg acaatccgat gaatgtcatt ataaaagctg tagttactgc ctcgacgcta
     7081 ctgatggtat cttttagttc attcgaaacc tcagcgcaat ccccactgtt aaaagagcaa
     7141 attgaatcca tagtcattgg aaaaaaagcc actgtaggcg ttgcagtgtg ggggcctgac
     7201 gatctggaac ctttactgat taatcctttt gaaaaattcc caatgcaaag tgtatttaaa
     7261 ttgcatttag ctatgttggt actgcatcag gttgatcagg gaaagttgga tttaaatcag
     7321 accgttatcg taaacagggc taaggtttta cagaatacct gggctccgat aatgaaagcg
     7381 tatcagggag acgagtttag tgttccagtg cagcaactgc tgcaatactc ggtctcgcac
     7441 agcgataacg tggcctgtga tttgttattt gaactggttg gtggaccagc tgctttgcat
     7501 gactatatcc agtctatggg tataaaggag accgctgtgg tcgcaaatga agcgcagatg
     7561 cacgccgatg atcaggtgca gtatcaaaac tggacctcga tgaaaggtgc tgcagagatc
     7621 ctgaaaaagt ttgagcaaaa aacacagctg tctgaaacct cgcaggcttt gttatggaag
     7681 tggatggtcg aaaccaccac aggaccagag cggttaaaag gtttgttacc agctggtact
     7741 gtggtcgcac ataaaactgg tacttcgggt atcaaagccg gaaaaactgc ggccactaat
     7801 gatttaggta tcattctgtt gcctgatgga cggcccttgc tggttgctgt ttttgtgaaa
     7861 gactcagccg agtcaagccg aaccaatgaa gctatcattg cgcaggttgc tcagactgcg
     7921 tatcaatttg aattgaaaaa gctttctgcc ctaagcccaa attaacagac tatcagcact
     7981 atctaagccg ctgactctgg ttgtacacta aagctatggt ttgaaattgg agtaggttat
     8041 gcagttatta ggttcagtgg cttccccttt tgttcgtcgt ttacgtttag tactggcagg
     8101 gcaaccttat cagtttgtag cgcttaatat ttttgagtct gaaggccgtt cagtgttggt
     8161 acaacataat ccggcacgca aagtgcctgt gttagtggat ggagagcagg ttatttttga
     8221 ttcaggcgta atttatcgtt atttggcttc gaaactgaaa ttcaaaccat tgagctggga
     8281 tcaggaaaac ggtctgacga ccatcaatgc ctgcacagac tccttggttg aattactgct
     8341 ttgtaagcgc tcaggttttg acgtgactga agataaattg ttttttaatc ttcagcatga
     8401 gcgaattcag gcgacgctag aggcacttga gcaacaaatc agggcagggc atttcggtga
     8461 ctgggactat cctggtatca gtctgttcac tttaatcgac tggatattgt tccgcgattt
     8521 agtcgactta aaacccttcc ctgtattatt acagttcaga aatgcgcatt taaaccggcc
     8581 gatggtcgct gaaaccgacc cgcgtttaag ctaaaaacaa caggtcagag ccaagactct
     8641 gacctttatt atttattcca caccaataaa gccgccggtt tgatgcgccc ataattgagc
     8701 gtaaataccg cctttggcga tcagttcctg atgactgcct tgttccacaa tacgaccttg
     8761 atccagaacg atcagcctgt ccatagctgc tatggtagat aaacggtgtg caatggctat
     8821 aaccgttttg cctatcatca actgagtcag actatgctga atagctgatt ctacttcgga
     8881 gtccagcgct gaggtggctt catccaaaat cagaataggg gcgtttttca gtaaaacccg
     8941 agctattgca atacgttgac gttgaccacc agaaagcttg actccacgtt cgcccacctg
     9001 agcgtcgtag ccactgttgc ctttaggatc ggtaagctcc tgaataaaag catcggcttc
     9061 ggctaaacgg gctgcttcaa tcatttccgc ttcggtagcg ccaggacgac catataaaat
     9121 attttccctt acagtacggt gtagcaggga ggtatcctgg gtcaccatag ctatatgagc
     9181 gcgaagactt tcctgtgata cagttttgat gtcctgaccg tctatcaaaa tctggcctga
     9241 attgacatca taaaagcgca gcagtaagtt caccagcgtg gatttaccag caccagaacg
     9301 gccgactaaa cctacttttt caccgggttt aatcgacaag tccagaccat caatcacagg
     9361 accatgttca cctgctgctt tgccgtagtt aaagttcagt tgcttaaact caatctgacc
     9421 ttgtggcact tcaagcggct tcgcatcagc tttgtcgatg atttgctgag gctgagacaa
     9481 agtcgcaata ccatctgcca cagtacctat gttttcaaac agtgcactga cttcccacat
     9541 gatccactgc gacataccat ttaaacgcag cgccagactg actgcgatgg caatagagcc
     9601 cacagtgacg gcattgacag accaaagcca tatcgccagc gtggcaatag agaacaccaa
     9661 cagatagttc agaccctgca cacaaatatt gagccaggta gccagtcgca tttgtctgta
     9721 cacaggcacc agaaacagct gcatgctatc gcgggcgtat tctgactcac gagccgtgtg
     9781 tgaaaacagt ttaatagtgc tgatattggt gtagctgtcg acaatacggc ctgtcatttc
     9841 tgaacgggca tcggcttgtt ctgttgcaac ttgtttcagt ctcggcacaa aataaaactg
     9901 caagccggtg tatatgacta accaggcaat catcggcagt accaagcgcc aatctgcatc
     9961 ggcgatcaga tacaacatag agccaaaata caccaccaca tacaccatca catccagcag
    10021 cttggtggcc gtttcgcgca ctgccaaagc cgtttgcatc actttagtgg cgatgcgacc
    10081 agcgaattca ttctggtaga aacccaaact ttgtttcagt aaataacgat gcgccagcca
    10141 gcggatcgac atagggtagt tacccaatat agtttggtgg atcagggctg agtgaaaaaa
    10201 taccaaacca ggcaacacca gcaacatcac tatggccata gtgatcaagg tatcctgctc
    10261 ttcctgccag aaagtagccg gattcttggt taccaaccaa tcgactaatt gccccatata
    10321 gccaaataag gacacttcta atgcggccag taaggctgtc gcaatagaca tcaggatcag
    10381 aggcaacacc atgccttgac tgtaatgcaa acaaaatgca aacaggcctt gaggtggctg
    10441 agttggctct ttatcaggga aagggttggt taagcgttca aaaaagccca gcataaaatt
    10501 cctctgcagc aacgaaaaag gcagttattg tacgtcaaag tttaaaaaac agatgtaact
    10561 atttgatgaa agcccggttt agaacggcca tcttatttta taaccgatag cttgtgactc
    10621 gcttttttgc tgaacagaac agcagattgt tgaaaataaa tacaaaaaat ctgaaaaatc
    10681 caaaagatgc tatatcacat gaactcagca gcttagattt attgaaggac cgttaatagg
    10741 taataactgg aaaatctata acttagcttc tgttttgtca gcttgcaaag gactttttgc
    10801 tttctacact gaaaatacag agtacccgaa tcagggtgtt gtctcgtctt acaggagtgt
    10861 tgaaatggat gccaaagaat tattggtcta catgaagcag gcagaactgc aagctgagtt
    10921 agtcgttgag gctggtcagc aactggacag agccatcaaa caattacatg actggtctga
    10981 agactgggat tgtcagcgcc gggcttgtga agatatgtac gatgccgtgc atttaattct
    11041 gatccatagc tatcaattat cccggatttt ctggcccgcc aagtgttgcg gagaactggg
    11101 gctggatttg tgtcatagag ccatggcgct gcgaagtgaa atcaacctgc ctgatctaaa
    11161 ccatccactg cggaatgagg cgttatggcg tcatgcagat gagctggatc attcagtgcg
    11221 ggataatact gctctgcgtc gttatcaagc gcatcattta accggtttta atcaggtgat
    11281 cacctggatg gataatgaag ccatgttttg ctggcttgaa cctgccagta aaacctttgt
    11341 gtttcatgcc gaggagtttg ctttagccca attactggat gctgtgcatc aggttcagca
    11401 agatattcag aattttctta acaagcagca tcagtcaaat ctaaaggtgg ccaaagctgg
    11461 cgtgcatcac tatgagaagc agtggggggc atttaaaata agacaagaca gatcttgtcc
    11521 acagctttgt tgttatgact acttatctaa tttaataaat ccgtaggcag aaatctcgct
    11581 gagcttatgt tctctgatct tttttgcgac ttctgcttgg tagtcttcaa tgtacaggtg
    11641 caaaaaatct ttaaactctt catccaaagc acgtctatcc acagagttac cgaaccgttg
    11701 cgcttcgtat gcaagcaggc ataatctatg cgcccggatc tccatatcag cggccacctg
    11761 cttttcgata atgtttaatg catctgacat tccaatcaac ttcttgtaga aaaacagact
    11821 taacagtaaa aagccaaacg taattgcaga cataacaaaa gtcagcattc ctgaagttcc
    11881 tttctgtgct tgacggctcc tgatatggac cataaaaata tcgctaaaat tgctgcgata
    11941 tttatagctg gtattccata tttgtatata ccacccaata gatcagtgcc aaatatgact
    12001 ctgtctgtga atctcgctac ctgcagaaca gagtgcatca agatgcttaa acaaatgaat
    12061 tgagtgattt gttcaaccgc ccatacgaat tttctatgaa taacccagat gataccaagc
    12121 gtcaatgttt gacatatcac ccaacttggg taccaaagta agcgagcgag ctcaggagat
    12181 gtttcagata tccccatcag caaaggagca atcctgtctt gagctaatcc cgataaagtg
    12241 agtatcaata tggttattcg tgcagattta ctggccgacc agactaagga cagcagtaga
    12301 gaacctatgc acaacaccca taagtactca gcaagagtcg taataaatgt ccccacaaac
    12361 tacctcttat tttggtggtt cattacccca gccaccacct aatgtagtca gtgttggatt
    12421 tattgcttta gattcttgct gctctgcagc cagcttcgcc tttgcttcag cagataaggt
    12481 gacagtgtct gcagtagagg gtgctgttgt agtggtggtt ttagcctgag cagcaggagc
    12541 aacagtttgt attgttgatg tagccgctgt gcccggagta tttaagttga tttgcataac
    12601 tgttccttac cattgtcact aaatcagaaa acaaatgtac cgagggcttt actaagcttg
    12661 ccccttccgc cgttgtcata atcggttatg gcatcgcatt ttattttctt tctctggttc
    12721 tgaaatccat ccctgtcggt gttgcttatg cagtctggtc gggactcggc gtcgtcataa
    12781 ttacagccat tgcctggttg cttcatgggc aaaagcttga tgcgtggggc tttgtaggta
    12841 tggggctcat aattgctgcc tttttgctcg cccgatcccc atcgtggaag tcgctgcgga
    12901 ggccgacgcc atggtgacgg tgttcggcat tctgaatctc accgaggact ccttcttcga
    12961 tgagagccgg cggctagacc ccgccggcgc tgtcaccgcg gcgatcgaaa tgctgcgagt
    13021 cggatcagac gtcgtggatg tcggaccggc cgccagccat ccggacgcga ggcctgtatc
    13081 gccggccgat gagatcagac gtattgcgcc gctcttagac gccctgtccg atcagatgca
    13141 ccgtgtttca atcgacagct tccaaccgga aacccagcgc tatgcgctca agcgcggcgt
    13201 gggctacctg aacgatatcc aaggatttcc tgaccctgcg ctctatcccg atattgctga
    13261 ggcggactgc aggctggtgg ttatgcactc agcgcagcgg gatggcatcg ccacccgcac
    13321 cggtcacctt cgacccgaag acgcgctcga cgagattgtg cggttcttcg aggcgcgggt
    13381 ttccgccttg cgacggagcg gggtcgctgc cgaccggctc atcctcgatc cggggatggg
    13441 atttttcttg agccccgcac cggaaacatc gctgcacgtg ctgtcgaacc ttcaaaagct
    13501 gaagtcggcg ttggggcttc cgctattggt ctcggtgtcg cggaaatcct tcttgggcgc
    13561 caccgttggc cttcctgtaa aggatctggg tccagcgagc cttgcggcgg aacttcacgc
    13621 gatcggcaat ggcgctgact acgtccgcac ccacgcgcct ggagatctgc gaagcgcaat
    13681 caccttctcg gaaaccctcg cgaaatttcg cagtcgcgac gccagagacc gagggttaga
    13741 tcatgcctag cattcacctt ccggccgccc gctaaatatc tccttttggg ttgttaataa
    13801 aacatccaat aagttgactg tgcgtgaaaa agaaagtttt gtgtgatggc gttgaagatc
    13861 gcaccgttaa gctcttatgt gggatggtgc agagctcgac gactaccgat aaaacgcaac
    13921 cgccgcaaac agacaagaaa aagccccaac tgataacagt tggggcttca gtattgtgat
    13981 tggtggagca atagcaccct gaacccaaaa ccttctcgct caaccggtag tggctgataa
    14041 caactcgtga gggctattgc gggttaagca tttagcgatg tctagggcca gactggacgt
    14101 ctgaacgcaa gccgctgata ctgtacataa ccacagtatc agcggaggat acccatgtcg
    14161 ctggcaagga acgccacggc gagtcaatcg cccactcaaa caaacggtta cgaacgccac
    14221 caacccgacc agacgctgct ctaccagctg gttgagcagc actacccagc cttcaaagcc
    14281 tcactcgaag cccaaggtca acacctgcct cgctacatcc aacaagaatt caacgacctc
    14341 ctccaatgtg gccgtctgga gtatggtttc atgcgggttc gctgcgagga ttgtcatcac
    14401 gagcgtctgg tcgccttcag ctgtaaacga cgcggctttt gccctagctg cggtgcccgc
    14461 cggatggccg agagtgcggc gctgctgata gacgaagtct tccccaagga gcccattcgc
    14521 cagtgggtgc tcagctttcc tttccagcta cgctttttgc tggctcgcca tccccagctg
    14581 atgggccagg tcttgagtat cgtctatcgt acactctcaa ctcatctgat caaaaaagcc
    14641 ggttacacca aagcctctgc acaaactggc tcagtgactc ttatccaacg ctttggctcc
    14701 gcgctaaatc tcaatgtcca ctaccacatg ctgtttctcg atggtgtcta tgccgaagat
    14761 gactatggca agcaacgctt ccatcgtgtc aaggcaccca cttacgatga gctgaatacg
    14821 ctcgctcaca ccctcagcca tcgcatcgct cgctgcatgg aaaagcgtgg gattttggag
    14881 cgtgatgccg agaatacgtg gttgacactg gaagagggcg aagacgatac gctgactcaa
    14941 ttacatggtg cttcggttac gtatcgcatt gccgtcggcc cccagcaagg gcgcaaagtc
    15001 ttcaccctgc aaaccttgcc agggcgtgag gataaagccg actcaagcag tcgagtagcc
    15061 aaccatgctg gtttctcgct acacgccggt gtgatggccg aagcgcatca gcgggataag
    15121 cttgagcgct tgtgtcgcta cattagtcgg ccagcggttt cagaaaaacg tctggcatta
    15181 accgccaatg ggcaggtgcg ttacgagctc aaaactccgt accgcaatgg caccacccat
    15241 gtgatcttcg agccgctgga cttcatcgcc aaactcgctg cgttggtacc taagccgcga
    15301 gtcaacctca cacgcttcca cggcgtcttt gcaccgaaca gcaaacaccg agttcaagta
    15361 acacccgcca agcggggcaa gaagcccgac aaatcggaag gtctcgatac taactggcgt
    15421 gacaagagtc ctgcagagcg ccaccgcgcc atgacctgga tgcaacgcct caagcgagtc
    15481 ttcaatattg atattgaagt ctgcgaacac tgcggcggtc acgtcaaagt gattgccagc
    15541 atcgaagatc cgaaggtcat tgagcagatt ctcaagcatc tgaaacagaa aacagccaag
    15601 gcgaatgccg ccaagcagcg tgagctgcca ccagaacgag cgccgccact gactcccagc
    15661 ctgttcgatc catcacagag tcgtctcttt gactgacgac cccaaatcca acactgctca
    15721 acactgccaa cttttaaacg gggcggtggg gcagtttgta tctctcgagc tatcaggcta
    15781 gagattttac cgccaaatcg aaccttatta gagcggttta ggctggaccg gcagttaaaa
    15841 ttggggcttg agcggtaaac gagtgaggga atttcaggta agatacttcg gatgaggagc
    15901 aaaaaggtgg tttatacttc ctatacccag gcattgatgg ggattattcc tggcggtggt
    15961 ggtactcaat atctttcaca gcgtatgaca cgggggcgtg cattagaggt aattcttggt
    16021 gctgacctta ttgacgcttt gctagccgaa cgatatggtt gggtaaatcg tgcgcttccg
    16081 gcaaatgagt tagacgcttt tgttcatcgc atcgccacaa atattgcagc tttacctgaa
    16141 ggggtcatcg ccgctgcaaa gaaagcaatc ccaccaacgg atttaagtga agacttcctt
    16201 cgagagcaca aggcatgggc tggtctgttt gcgcgtccgg ctgctgaaaa actcattcgt
    16261 ggcggcttgc aggcaggtgc tcaaacaaaa gtgggcgaac aggatttgga gcaactactc
    16321 cgcgatttgt ctgcatcctg aggtcttgct gctgtctaat attctgctct agcttattct
    16381 tgagatttga gacagagaaa tacagcaacc cattttcctt aagcctagcg ctatttatgc
    16441 aattgagagg taatgacaaa agtttgatgc attgaccctc tatagacaat aagccatatt
    16501 tttgctacag tgaacctaat taagatcatc tatttactag gcctcgcatt tgcgaggttt
    16561 ttaatgctga ataaaaggaa aacttgatgg aattgcctaa tattattcaa caatttattg
    16621 gaaacagcgt tttagagcca aataaaattg gtcagtcgcc atcggatgtt tattctttta
    16681 atcgaaataa tgaaactttt tttcttaagc gatctagcac tttatataca gagaccacat
    16741 acagtgtctc tcgtgaagcg aaaatgatga gttggctctc tgataaatta aaggtgcctg
    16801 aactcatcat gacttttcag gatgagcagt ttgaattcat gatcactaaa gcgatcaatg
    16861 caaaaccaat ttcagcgctt tttttaacag agcaagaatt gctttctatc tataaggaaa
    16921 cactcaatca gttaaatgca gttgctattt ttgattgccc atttatttca agcattgatc
    16981 atcggttaaa agagtcaaaa ttttttattg ataaccaact ccttgacgag atagatcaag
    17041 atgattttga ggctgaatta tggggagacc ataaaactta cctaagtctt tggaatgagt
    17101 taaatgagac tcgtgttgaa gaaagattgg ttttttctca tggcgatatc acggatagta
    17161 atatttttat agataaatct ggtgaaattt actttttaga tcttggtcgt gctggattag
    17221 cagatgaatt tgtagatata tcttttgttg aacgttgcct aagagaggat gtatctgagg
    17281 aaactgctaa aatattttta aagcatttaa aaaacgatat gcctgacaaa aggaattatt
    17341 ttttaaaact tgatgaattg aattaactcc aagcaatatc taaaaatact tagctgtatt
    17401 tttaagttgc taatttttaa ataaataagt gaaaaaagtt agtggaacta ctgatttaaa
    17461 gttttatata gccaataaat ctaaattttg gtttttaaaa tgaacttatt taaaatagct
    17521 aaagctgttt attagcttaa cttgtgattt aagttttttt gaatataaaa ttgttaattt
    17581 attagcttta caagtttatt taaatttcat cgtgcaacat ttttaaccaa ttttattatc
    17641 gatggtattt ttttgtctgc ttttcttttc ctagtctttt atctatccgt caaccatata
    17701 gtattttatt aaattcttat gggaaatgac gaatgttaaa ttatcttaag agctttaata
    17761 atatcaatac ttatttgatt ttatcgataa ttctgctgtt aattataata tcagaggtgg
    17821 tcccacttgt ttgaacaact aaaagcgtat ttataagtga tattccgctc tagttaagcc
    17881 accttgtttt gttggggtag ctgatcatag taaaaatcat ttggtgtcat tttgtctaga
    17941 ctcgaatgag gtcgtttcaa attataaaac tcaaaatatg cacttaattg ctttttcgca
    18001 tctgtgacac tgctataagc tttgagatac acctcttcat atttaacgct ccgccataat
    18061 cgttcaacca tcacattatc tacccatcga cctttaccat ccatactgat ttgaatgcca
    18121 tttgatttca atacatcaat aaatgcatca ctggtgaact gactgccttg gtctgtattc
    18181 aatatttcag gtgatccata tttttcaatc gcttcattta aaaccgaaat acaaaaatcc
    18241 acctccatac taatcgatac cctatgcgca agtaccttgc ggctatgcca atcaatcaca
    18301 gcacataaat aaacaaagcc ttttgccata gggatatacg ttatatccgt agaccacact
    18361 acctattttt actggtggcc gcaaccgagc taacttaaca ctggccgagg tcagaaaaga
    18421 tatcgcaata gcagagtacg agtaccaaat ccaaagtgct tttcgcgaag ttgccgatgc
    18481 tttagtagca agtagttcat tgcaacggga agaaaacgct caagcggaac tggcgagttc
    18541 agccaataaa acattgcaat tagccgaagc gcgttatcgt gcgggtgttg atagcaatct
    18601 gcgttatttg gatgcacagc gtcagcattt tagtgcccaa caaaatctga tcacggtaag
    18661 tacacagcat caactcgcac ttgtcgattt atttcgagca cttggcggta actggtatac
    18721 caaaacgcat taattactgg ctcaataaaa tactcagtaa agtaaaacag ctcgctatta
    18781 cagtgagctg tttttttgtt tgcagaatat cagtacaaac tcaacgtgag caagagctgc
    18841 agcggctgca ggcagagcta cggttggcac agcaagctct gagtgttaaa caacaagagg
    18901 tggtaacggg atcctgattt tttttcacaa atcctaattt aacatgttgt ttttataaat
    18961 aaatattttt cacgcgtcaa tgaacagcgc cgaagaatag agagtataaa aaaatctgtg
    19021 taagtggcat tctatccatg tatttgaaag gaatgaagaa tgccagtatc agaccagctt
    19081 atcgaccagt tattagctga ctacaaatcc ccggaagacc tgcttggtga gcaaggtatc
    19141 cttaagcagt tgaccaaaaa gcttgccgaa cgcgcccttg aagccgagat ggagcagcat
    19201 ctaggttatg ccaaacatga tgccgccggt aaaaacaccg gtaactcccg caacggtaaa
    19261 agtcgtaaat cagtgcgcct gagggatccc cacaaaattt ccattcatac aatcagctat
    19321 cagcctgttt gattactgcc cagtcccact gaaccaccca ctgtagtatt tgtttaagtc
    19381 cctgctgata atattgcctg cgtattcgct gtttgggttc tttgcaaagt aatatcccaa
    19441 ggaaattcag ggccaatacc cgcctatttt taacggtgtt agcttgataa cgcaggtgca
    19501 aacccgcttt ctccgctgcg ctacctagca ggtaatgaaa ccaattaacc aatgcggcca
    19561 gtagtagcag tatctctaag cgagatttct tcttggtacc atgcaaatcg ctacccaggc
    19621 catagcggtg acttttctga tcacggaagc tttcttcaat ttgcattcgg ctactgtagc
    19681 acttagcaat tttatccgca tacccatggc agtcagctaa ggatgacacc aacaaccatg
    19741 gttccttata cgtcttattt ttatcgcgtt tcaatagctt ataacctttg ccaaccagga
    19801 cggcctgcgt ttcatagtgt tgtgtttggg caagcatgat ttttcctaca ctttttggat
    19861 ccttcttcgc ttgccgataa agctgattaa cactgataaa cttgtcctgc tctgccaatt
    19921 taagcttcac attgcctcga actctagcta cataatgcca tcccagctta cgcacttgtt
    19981 tcagccatgg aactttaaac cccgcgtcag tgacaattac gggcttacag tccttgggta
    20041 gcatggcttt aagctgcttt aaaaacgccc cgtgtaggtg tgggcaggta taatcttctg
    20101 cggcggcaat cttctgtagc agagtcaacg ctctaccgtc agcggcaatg ctggcacgca
    20161 ggataaagtg tcgcttggca gtatcggcat tgctccagtc aaccaaaatc atcggcttag
    20221 ttttatggcc aacaatagaa gccgtcagcg cagcataaat caatggcagc tctcgttgca
    20281 ggttaggatt attgagtaga cgatctgccc gtttgatact gaccttatct gaagagccag
    20341 gcatcgcccg gccaatcgca gtaacggtgc aacacgcatc ctttgccagg gcggttaccg
    20401 catctagcaa aaccgaaaat cgggctttat gcattgattt tggcgtgaca aaggtgagga
    20461 aatcagcgag catagctttt acattcatgg tgagcatccg cggtgtggga gttttggcga
    20521 atgatcagat caggaaccgc catgaatgtt ccccaatcaa ctaacatttt attttaacta
    20581 cagaatttct ggggatacct cagctaatgt attcggatct cttttagatt cgactgaatg
    20641 cgtggctgat tttttctgtt taaagctaaa tgaaaaacca gtaatagatc tacctgtttt
    20701 atgctgttca actttgacaa taatatcggt atgttcattt acttgtttta atgcaatgtc
    20761 taaaacatat tttttaaaat catacattcg tttgtattca gtctcgagta cacctatttt
    20821 ttgtctaaaa tcatacatag ttatgagagg cgtttttcca gtactacgcc atgcaatcaa
    20881 tatttcatat aaacgaacag cataagcact tgttaaatta cttatttgtt gtatttcata
    20941 ctttgtaaat tgttcttcta acctagtaat taaaggcaca atagcagggg caaaaataag
    21001 tctaacgaca gcttcattat caatataagc cacctcgctc acccatcttg atttgtgatt
    21061 aatagtgtta cctttttcac taagactctg ataactgaat tgtcttgcaa acaagtcatc
    21121 gcaagcatct tttaacgcct gataagccgt atttcgatgt acacggcact gttgcaaata
    21181 gtcggtggtg ataaacttat catccccttt tgctgatgga gctgcacatg aacccat
//
