LOCUS       In384                  13903 bp    DNA     linear       29-SEP-2020
DEFINITION  Aeromonas caviae.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Aeromonas caviae
  ORGANISM  Aeromonas caviae
            Unclassified.
REFERENCE   1  (bases 1 to 13903)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of In384
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13903)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..13903
                     /organism="Aeromonas caviae"
                     /mol_type="genomic DNA"
     repeat_region   1..25
                     /gene="IRi_In384"
     CDS             complement(203..1216)
                     /gene="intI1"
                     /codon_start=1
                     /product="Integrase"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     misc_recomb     1297..1359
                     /gene="attI1"
     CDS             1361..1858
                     /gene="dfrA12"
                     /codon_start=1
                     /product="Dihydrofolate reductase"
                     /translation="MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGK
                     VVVMGRKTFESIGKPLPNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVA
                     GGAEIYTLALPHAHGVFLSEVHQTFEGDAFFPMLNETEFELVSTETIQAVIPYTHSVY
                     ARRNG"
     misc_recomb     1853..1942
                     /gene="attC_dfrA12"
     CDS             1970..2260
                     /gene="gcuF"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MFIQTAFSFSGVIQCLFCLFSGLRLHGLRRFSVFLASSPCVASA
                     SSYRFCSAVPPRWRSVFSRLAPVAKFKLSVLASGSNISVKPTRILRSAYLAR"
     misc_recomb     2203..2262
                     /gene="attC_gcuF"
     CDS             2365..2712
                     /gene="qacED1"
                     /codon_start=1
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             2706..3545
                     /gene="sul1"
                     /codon_start=1
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     misc_feature    3673..3849
                     /gene="truncated orf5"
                     /product="Truncated hypothetical protein (pseudogene)"
     repeat_region   3850..3887
                     /gene="IRL_chrA"
     CDS             4032..5237
                     /gene="chrA"
                     /codon_start=1
                     /product="Chromate transport protein ChrA"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRR
                     RWLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILF
                     ALGISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLV
                     PSAWGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVL
                     AELMPSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAV
                     PGPLFTFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQA
                     ALAGINAAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGA
                     AGWLLSVAL"
     CDS             5248..5553
                     /gene="orf98"
                     /codon_start=1
                     /product="PadR family transcriptional regulator"
                     /translation="MTDKDLYGGLIRLHILHHAAEEPVFGLGIIEELRRHGYEMSAGT
                     VYPMLHGLEKKGYLTSRHERTGRRERRVYDITEQGRTALADAKTKVKELFGELVEGG"
     repeat_region   complement(5596..5620)
                     /gene="IRt_In384"
     repeat_region   5719..5732
                     /gene="IRL_IS6100"
     CDS             5780..6544
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS6100 transposase"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     repeat_region   6585..6598
                     /gene="IRR_IS6100"
     CDS             6710..6949
                     /gene="orf240"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MLSRRARAATPTCPTHPPHRSPPPAMARLFAGRIGGVSSRPGTP
                     TPAQPYGSDSLSKNRPGALTQVSGWSPFVSRRPEW"
     CDS             complement(7037..7621)
                     /gene="mphR(A)"
                     /codon_start=1
                     /product="Negative regulator"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAAL
                     IQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVN
                     YLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
     CDS             complement(7621..8859)
                     /gene="mrx(A)"
                     /codon_start=1
                     /product="Positive regulator"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLL
                     RPLFGIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVG
                     ARISAQNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRT
                     PPELLGRVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQ
                     FATMAAAATASAPTHTEGEH"
     CDS             complement(8856..9761)
                     /gene="mph(A)"
                     /codon_start=1
                     /product="Macrolide phosphotransferase"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
     repeat_region   complement(9831..9844)
                     /gene="IRR_IS26"
     CDS             complement(9883..10587)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS26 transposase TnpA"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     repeat_region   complement(10637..10650)
                     /gene="IRL_IS26"
     CDS             10738..11553
                     /gene="aphA1"
                     /codon_start=1
                     /product="Aminoglycoside phosphotransferase"
                     /translation="MSHIQRETSCSRPRLNSNMDADLYGYKWARDNVGQSGATIYRLY
                     GKPDAPELFLKHGKGSVANDVTDEMVRLNWLTEFMPLPTIKHFIRTPDDAWLLTTAIP
                     GKTAFQVLEEYPDSGENIVDALAVFLRRLHSIPVCNCPFNSDRVFRLAQAQSRMNNGL
                     VDASDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVG
                     RVGIADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF"
     repeat_region   complement(11691..11704)
                     /gene="IRR_IS26"
     CDS             complement(11743..12447)
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS26 transposase TnpA"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYISSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     misc_feature    complement(12494..13762)
                     /gene="truncated tniA"
                     /product="Truncated DD(35)E transposase TniA"
     repeat_region   complement(12497..12510)
                     /gene="IRL_IS26"
     repeat_region   13879..13903
                     /gene="IRt_In384"
ORIGIN      
        1 tgtcgttttc agaagacggc tgcactgaac gtcagaagcc gactgcacta tagcagcgga
       61 ggggttggat ccatcaggca acgacgggct gctgccggcc atcagcggac gcagggagga
      121 ctttccgcaa ccggccgttc gatgcggcac cgatggcctt cgcgcagggg tagtgaatcc
      181 gccaggattg acttgcgctg ccctacctct cactagtgag gggcggcagc gcatcaagcg
      241 gtgagcgcac tccggcaccg ccaactttca gcacatgcgt gtaaatcatc gtcgtagaga
      301 cgtcggaatg gccgagcaga tcctgcacgg ttcgaatgtc gtaaccgctg cggagcaagg
      361 ccgtcgcgaa cgagtggcgg agggtgtgcg gtgtggcggg cttcgtgatg cctgcttgtt
      421 ctacggcacg tttgaaggcg cgctgaaagg tctggtcata catgtgatgg cgacgcacga
      481 caccgctccg tggatcggtc gaatgcgtgt gctgcgcaaa aacccagaac cacggccagg
      541 aatgcccggc gcgcggatac ttccgctcaa gggcgtcggg aagcgcaacg ccgctgcggc
      601 cctcggcctg gtccttcagc caccatgccc gtgcacgcga cagctgctcg cgcaggctgg
      661 gtgccaagct ctcgggtaac atcaaggccc gatccttgga gcccttgccc tcccgcacga
      721 tgatcgtgcc gtgatcgaaa tccagatcct tgacccgcag ttgcaaaccc tcactgatcc
      781 gcatgcccgt tccatacaga agctgggcga acaaacgatg ctcgccttcc agaaaaccga
      841 ggatgcgaac cacttcatcc ggggtcagca ccaccggcaa gcgccgcgac ggccgaggtc
      901 ttccgatctc ctgaagccag ggcagatccg tgcacagcac cttgccgtag aagaacagca
      961 aggccgccaa tgcctgacga tgcgtggaga ccgaaacctt gcgctcgttc gccagccagg
     1021 acagaaatgc ctcgacttcg ctgctgccca aggttgccgg gtgacgcaca ccgtggaaac
     1081 ggatgaaggc acgaacccag tggacataag cctgttcggt tggtaagctg taatgcaagt
     1141 agcgtatgcg ctcacgcaac tggtccagaa ccttgaccga acgcagcggt ggtaacggcg
     1201 cagtggcggt tttcatggct tgttatgact gtttttttgt acagtctatg cctcgggcat
     1261 ccaagcagca agcgcgttac gccgtgggtc gatgtttgat gttatggagc agcaacgatg
     1321 ttacgcagca gggcagtcgc cctaaaacaa agttagccat atgaactcgg aatcagtacg
     1381 catttatctc gttgctgcga tgggagccaa tcgggttatt ggcaatggtc ctaatatccc
     1441 ctggaaaatt ccgggtgagc agaagatttt tcgcagactc actgagggaa aagtcgttgt
     1501 catggggcga aagacctttg agtctatcgg caagcctcta ccgaaccgtc acacattggt
     1561 aatctcacgc caagctaact accgcgccac tggctgcgta gttgtttcaa cgctgtcgca
     1621 cgctatcgct ttggcatccg aactcggcaa tgaactctac gtcgcgggcg gagctgagat
     1681 atacactctg gcactacctc acgcccacgg cgtgtttcta tctgaggtac atcaaacctt
     1741 cgagggtgac gccttcttcc caatgctcaa cgaaacagaa ttcgagcttg tctcaaccga
     1801 aaccattcaa gctgtaattc cgtacaccca ctccgtttat gcgcgtcgaa acggctaacc
     1861 attccgtcaa cgggacgcca aaatgctgcg cattttggtt ccctccgctg cgctccggct
     1921 ctcgttacgt ccaacgttag caccactgaa acccagcttt atttagctca tgtttattca
     1981 aacggcattt agcttttcag gcgttattca gtgcctgttt tgcctttttt ccgggcttcg
     2041 cctgcatggg ctgcgcaggt tttcagtctt tttggcctct agcccttgcg tagcaagcgc
     2101 aagcagctat cgtttttgca gtgctgtgcc gcctcggtgg cgcagcgttt tttcacggtt
     2161 agcgcccgtc gccaaattca agttatccgt tttggcttct ggttctaaca tttcggtcaa
     2221 gccgacccgc attctgcggt cggcttacct cgcccgttag atgcactaag cacataattg
     2281 ctcacagcca aactatcagg tcaagtctgc ttttattatt tttaagcgtg cataataagc
     2341 cctacacaaa ttgggagata tatcatgaaa ggctggcttt ttcttgttat cgcaatagtt
     2401 ggcgaagtaa tcgcaacatc cgcattaaaa tctagcgagg gctttactaa gcttgcccct
     2461 tccgccgttg tcataatcgg ttatggcatc gcattttatt ttctttctct ggttctgaaa
     2521 tccatccctg tcggtgttgc ttatgcagtc tggtcgggac tcggcgtcgt cataattaca
     2581 gccattgcct ggttgcttca tgggcaaaag cttgatgcgt ggggctttgt aggtatgggg
     2641 ctcataattg ctgccttttt gctcgcccga tccccatcgt ggaagtcgct gcggaggccg
     2701 acgccatggt gacggtgttc ggcattctga atctcaccga ggactccttc ttcgatgaga
     2761 gccggcggct agaccccgcc ggcgctgtca ccgcggcgat cgaaatgctg cgagtcggat
     2821 cagacgtcgt ggatgtcgga ccggccgcca gccatccgga cgcgaggcct gtatcgccgg
     2881 ccgatgagat cagacgtatt gcgccgctct tagacgccct gtccgatcag atgcaccgtg
     2941 tttcaatcga cagcttccaa ccggaaaccc agcgctatgc gctcaagcgc ggcgtgggct
     3001 acctgaacga tatccaagga tttcctgacc ctgcgctcta tcccgatatt gctgaggcgg
     3061 actgcaggct ggtggttatg cactcagcgc agcgggatgg catcgccacc cgcaccggtc
     3121 accttcgacc cgaagacgcg ctcgacgaga ttgtgcggtt cttcgaggcg cgggtttccg
     3181 ccttgcgacg gagcggggtc gctgccgacc ggctcatcct cgatccgggg atgggatttt
     3241 tcttgagccc cgcaccggaa acatcgctgc acgtgctgtc gaaccttcaa aagctgaagt
     3301 cggcgttggg gcttccgcta ttggtctcgg tgtcgcggaa atccttcttg ggcgccaccg
     3361 ttggccttcc tgtaaaggat ctgggtccag cgagccttgc ggcggaactt cacgcgatcg
     3421 gcaatggcgc tgactacgtc cgcacccacg cgcctggaga tctgcgaagc gcaatcacct
     3481 tctcggaaac cctcgcgaaa tttcgcagtc gcgacgccag agaccgaggg ttagatcatg
     3541 cctagcattc accttccggc cgcccgctag cggaccctgg tcaggttccg cgaaggtggg
     3601 cgcagacatg ctgggctcgt caggatcaaa ctgcactatg aggcggcggt tcataccgcg
     3661 ccaggggagc gaatggacag cgaggagcct ccgaacgttc gggtcgcctg ctcgggtgat
     3721 atcgacgagg ttgtgcggct gatgcacgac gctgcggcgt ggatgtccgc caagggaacg
     3781 cccgcctggg acgtcgcgcg gatcgaccgg acattcgcgg agaccttcgt cctgagatcc
     3841 gagctcctag ggatcgcctc agaaaacgga aaataaagca cgctaagccg taagtaagcg
     3901 tgctcctgtg aaagccacag ctaaaactgc gtagtacaca tagaggtatt tttttctaga
     3961 tttatatcga atttcgttat cgaatttcgc ttattattga tcaactcgtt gcagatcatg
     4021 aaggcgaaag tatgacgaat aaccctaccg atgacagcag accatggtcg gtctttctta
     4081 tttttctgcg gcttggattg acatcttttg gcggccccat tgcgcacttg ggctacttcc
     4141 gcgccgaatt tgtcacacgg cggcgctggc tctccgaacg gagctatgct gacttggtcg
     4201 cgctttgtca gttcttgcca gggcctgcaa gcagccaggt cggcatagcg gtaggactgt
     4261 ctcgggctgg atacagcggg gcgctggctg cttgggctgg cttcacgctg ccgtctgcca
     4321 tagccttgat cctttttgcg ctcggcatct ccagctatgg cgattacgtc tcgcagggcg
     4381 cgttgcatgg cttaaaagtg gtggctgtgg ccgtggtcgc tcaagcagta tggggcatgg
     4441 cgcgtaacct atgcacggat gggctgcgag tcaccatcat ggcaattgct acctgcgtcg
     4501 ttttacttgt gccgtccgcg tggggacagg ttggcgtgat tgctatcgca ggcatcgcag
     4561 gccggttatt gttcaagcca gcgaaagttg ttgagcatga ccccctacct atcacggtca
     4621 gtcaccgggc cggcgtgctt tggctctcgc tgttctttgt cttgctgatt ggcctgccgg
     4681 tgttggccga actgatgcca agtcaaacca tggcaatggt ggattccttc tatcgtgtcg
     4741 gatcactggt gttcggcggt ggtcacgttg tgctgccatt actgcaagcc gaagtggtgc
     4801 cctccggctg ggtcaacaat gaatcctttc tcgcggggta cggggcagct caagcggtgc
     4861 ccggcccttt gttcacgttc gccgcgtttc ttggtgcctc gatgaacacc gccccgtcgg
     4921 gctggatcgg cggcattgtg tgtctgctgg ctatcttcgc gccctcgttc ttgctggtcg
     4981 tcggatcaat gccattttgg gagcgtttgc gccgcaatac aggcatccaa gctgcgctgg
     5041 ccgggatcaa tgccgctgta gtcggcttgc tgctggccgc gctgtatcag cctgtatgga
     5101 ctagcgccat ctttcagccg caagacttcg gcttggcatt agttgccctt gtcgcactta
     5161 tgttctggaa gctcccgccg tggctggttg tcctcggtag cggtgcagct gggtggctgt
     5221 tgagcgtcgc tctgtgaggc acaaaaaatg actgacaaag acctctacgg cggtttgatc
     5281 cgcctgcaca tccttcacca tgcagccgag gaacctgtct ttgggctggg gatcatcgaa
     5341 gagctacgcc gacacggcta cgagatgagc gctggcaccg tgtacccgat gctgcacggc
     5401 ctggaaaaaa aaggctatct gacctcacgc cacgaacgca ccgggcgacg tgaacggcgt
     5461 gtttatgaca tcactgaaca aggcagaact gcacttgctg atgcgaaaac aaaggtcaag
     5521 gagctgttcg gagagttggt agaaggtggt tgagtttttg cttctatgtc aggttgagct
     5581 ataccctaac tggattgtca ttttcagaag acgactgcac cagttgattg ggcgtaatgg
     5641 ctgttgtgca gccagctcct gacagttcaa tatcagaagt gatctgcacc aatctcgact
     5701 atgctcaata ctcgtgtggg ctctgttgca aaaatcgtga agcttgagca tgcttggcgg
     5761 agattggacg gacggaacga tgacggattt caagtggcgc catttccagg gtgatgtgat
     5821 cctgtgggcg gtgcgctggt attgtcgcta tccgatcagc tatcgcgacc ttgaggaaat
     5881 gctggcggaa cgcggcattt cggtcgacca tacgacgatc tatcgctggg tccagtgcta
     5941 cgccccggag atggagaagc ggctgcgctg gttctggcgg cgtggctttg atccgagctg
     6001 gcgcctggat gaaacctacg tcaaggtgcg gggcaagtgg acctacctgt accgggcagt
     6061 cgacaagcgg ggcgacacga tcgatttcta cctgtcgccg acccgcagcg ccaaggcagc
     6121 gaagcggttc ctgggcaagg ccctgcgagg cctgaagcac tgggaaaagc ctgccacgct
     6181 caataccgac aaagcgccga gctatggtgc agcgatcacc gaattgaagc gcgaaggaaa
     6241 gctggaccgg gagacggccc accggcaggt gaagtatctc aataacgtga tcgaggccga
     6301 tcacggaaag ctcaagatac tgatcaagcc ggtgcgcggt ttcaaatcga tccccacggc
     6361 ctatgccacg atcaagggat tcgaagtcat gcgagccctg cgcaaaggac aggctcgccc
     6421 ctggtgcctg cagcccggca tcaggggcga ggtgcgcctt gtggagagag cttttggcat
     6481 tgggccctcg gcgctgacgg aggccatggg catgctcaac caccatttcg cagcagccgc
     6541 ctgatcggcg cagagcgaca gcctacctct gactgccgcc aatctttgca acagagcccg
     6601 ccgtgctagt ctgctcggtg atggtggagt gaagccaacc cgcaatcggg ttatgaatct
     6661 gcatcgcgat tcgcaatcag ctgtctcttg agcatgtcga actcctgcga tgttatctcg
     6721 ccgtgctcgt gctgctacac caacttgtcc aactcatccg ccacaccgct ccccaccacc
     6781 tgcgatggcc aggttgtttg ctgggcgcat tggcggagta tcgtctcgac ccgggacacc
     6841 cacaccggca caaccttacg ggagtgattc actgtcaaag aatcggcccg gtgctctgac
     6901 gcaagtatcg ggatggtcac catttgtaag ccgtagacct gagtggtgat caagacttcg
     6961 ataccaccga ccgtaccggt actaatcgac gacggtcgtg ttcgtcgcct gccgcaggga
     7021 ctctgcacac ctccgtttac gcatgtgcct ggaggagttg gaaatcgtcg tgttcgggaa
     7081 acattaaaca caggatggca gcgatctgag ccagcacatg atcagctagc tcaccatccg
     7141 gatcgacggc ccactgcatc gtcgcgccag cgatgaccga gtgcaggagc aactcagctg
     7201 ccgcaggagc acctgggggc agtcgcttgc ggatcccctc caccaccgcg cggttccgct
     7261 ggatcgcaag cgtgcgtagc tccggcacct ggagctcgta ccaggagatg agatagttca
     7321 ccgagaagtc gttgcgagtg ttcatgctcc gaacgagcac ctgcaaaaat tcccagagcc
     7381 cttgcggccc tgcgcctatc ggtatcgcat tcaggtaatg ccgcacctgc tcgacgccgc
     7441 gctccatcat cctcaccagc agcgtatcgc ggttggtgaa gcgctggatt aacgctgcgc
     7501 gggagagccc cacctccttt gctactccgc tgagcgtgaa ctctatggga ccgcaacgct
     7561 tcagcactac ggtggcggcc tcgagtacct cgtcatcgga cttgagcttg gggcggggca
     7621 tcagtgttca ccttctgtat gggttggggc ggaggctgtg gctgccgccg ccattgtagc
     7681 aaattgaaga cggagcgaga gtagagccac gagccccgca aacacggccg atacaacgag
     7741 gccagggagc ggaccagcaa ggtcgacaaa cgcgccggcc gcaagcataa ccatgggcga
     7801 ggctgacagc atcaccgccg agaccgtgcc gagtacccgg ccgagaagtt ctggcggcgt
     7861 gcggttgtag atggcagcgt tgagaatggg agagactgag ccggtcagca gtcccacgag
     7921 cgcgcccaac aacatcagca ccggcacgcc tggcaactgt gaaagcagaa gcgagcccac
     7981 cgcagagcca caaaatgcca ccgccagcca gttctgcgct gatatccggg cgccgaccga
     8041 cgcatgaatg gcaatgccaa ggagaccacc agcccccatc attgaggaga acagcccgag
     8101 ctctgctact tggcgtcctg catctacaaa cagcgcaggc atgatgacgc tgccgttggc
     8161 gccaacgatg cccacgaaga tcatcactat accaaagaga gggcgcagca ggggttcgct
     8221 ccagagaaaa gcgacgccgg cgcgcatgga gagagtcgcc gtcgtggtca tcgtccgagc
     8281 ggcacgcgcg ggaagcaccc acgcgccgag cagacctgca aggacggagc agaacgccgt
     8341 cagcccgagc gttggcgcag cgccaagcag gccgattgcg gcccccccaa gggccgggcc
     8401 acctagaatc gcgacgttcc cgatcaccgc tttcagtgac gagacgcgct caacggagag
     8461 cccggcgacg tggccgagtt tgggcagctc actgtcctgc gcggccatac cgggtgcgtc
     8521 gaacgcggca ccgagcacca cgcaagcgat cagcccagtg ttcgagaggg cgccaacggc
     8581 atcgagcagt gggatgctcg ccatggccac gccgcccacc acacccgaga tcaatgcgac
     8641 gggcgcgcgc ccgaaccgat cgacgaggcc accaccaacc cacgcgccga tgatggtcgc
     8701 gatgacgctg ctagcggccg tggcgcccgc ccaggccgcg ctctttgtat gagacaggac
     8761 gaaccatgga agcgcgaggg ccgccaccgc gttgccgatc cggaagagaa aggtcgccgc
     8821 gaacagcgtc gcgagcgggc tatatcgacg ttcgctcatt ccgctgcggc gagctgcgcc
     8881 ttcgccgcag cgaggtactc ttcgttaccc gagtcgaggg cgaagagtgc gtaggtgacc
     8941 gccccgaacg caaggcgctc cgcgatgtgg tgggcgagcc gcggccacac ccggccaccg
     9001 gccgcttcat acgtgaggag gagcttcgcg agcccctctt caccaaagac cataaggtgc
     9061 gcggccatgt cgatggcagg gtcatcaacg cgggcctcgc tccagtcgat catcccgctg
     9121 acgcgctccg tgttgtcgat gagcacatgg cccacgtaga gatcgccatg caccaccacg
     9181 gagaaatctg gccacgacga atcgtcgtcg agccagcgct gccaccggtg gaggcgcttg
     9241 tcgttcacca cgaactcgcg tcggacgcgg tcaacgtcgt cggccacctt ctgacgggcc
     9301 tgcgtcggtg tacggatgag catccccgca tccacggcgg cggaaatggg gacggcatgc
     9361 agggcggcga gcgcggtcgc gaagctctcc gcgaagacct ccgagtcctg cggcacgacc
     9421 cagtcgggcg tggacgaacc aggctggatg accatcgcag tcgagtcttc gagcatggga
     9481 taggcaacga gctcggcgtt ggccacgcgc cagtccggca ccgcgaacgg caggcgattc
     9541 ttgagcattg ccagcacccg cgcctctggt tcgaccttcg cgcttacctc ggctcggcgc
     9601 gggatgcgca gcacccaccg acgtccatcg tcgacggtgg cgatcacgat cctatagtcg
     9661 agcccaagct cattgacagt cagcgggcca tggagcttga gcccatgtcg ggctgcaagt
     9721 gcgtacagtt gggaggtatc ggcggtcgtg actacggtca tgattcactc ctgagggctt
     9781 gacgggttta gccacctaaa tgtaacagtt acgtcggtta tattcaatcc ggcactgttg
     9841 caaagttagc gatgaggcag ccttttgtct tattcaaagg ccttacattt caaaaactct
     9901 gcttaccagg cgcatttcgc ccaggggatc accataataa aatgctgagg cctggccttt
     9961 gcgtagtgca cgcatcacct caataccttt gatggtggcg taagccgtct tcatggattt
    10021 aaatcccagc gtggcgccga ttatccgttt cagtttgcca tgatcgcatt caatcacgtt
    10081 gttccggtac ttaatctgtc ggtgttcaac gtcagacggg caccggcctt cgcgtttgag
    10141 cagagcaagc gcgcgaccat aggcgggcgc tttatccgtg ttgatgaatc gcgggatctg
    10201 ccacttcttc acgttgttga ggattttacc cagaaaccgg tatgcagctt tgctgttacg
    10261 acgggaggag atataaaaat cgacagtgcg gccccggctg tcgacggccc ggtacagata
    10321 cgcccagcgg ccattgacct tcacgtaggt ttcatccatg tgccacgggc aaagatcgga
    10381 agggttacgc cagtaccagc gcagccgttt ttccatttca ggcgcataac gctgaaccca
    10441 gcggtaaatc gtggagtgat cgacattcac tccgcgttca gccagcatct cctgcagctc
    10501 acggtaactg atgccgtatt tgcagtacca gcgtacggcc cacagaatga tgtcacgctg
    10561 aaaatgccgg cctttgaatg ggttcatgtg cagctccatc agcaaaaggg gatgataagt
    10621 ttatcaccac cgactatttg caacagtgcc ctctgatgtt acattgcaca agataaaaat
    10681 atatcatcat gaacaataaa actgtctgct tacataaaca gtaatacaag gggtgttatg
    10741 agccatattc aacgggaaac gtcttgctcg aggccgcgat taaattccaa catggatgct
    10801 gatttatatg ggtataaatg ggctcgcgat aatgtcgggc aatcaggtgc gacaatctat
    10861 cgattgtatg ggaagcccga tgcgccagag ttgtttctga aacatggcaa aggtagcgtt
    10921 gccaatgatg ttacagatga gatggtcaga ctaaactggc tgacggaatt tatgcctctt
    10981 ccgaccatca agcattttat ccgtactcct gatgatgcat ggttactcac cactgcgatc
    11041 cccgggaaaa cagcattcca ggtattagaa gaatatcctg attcaggtga aaatattgtt
    11101 gatgcgctgg cagtgttcct gcgccggttg cattcgattc ctgtttgtaa ttgtcctttt
    11161 aacagcgatc gcgtatttcg tctcgctcag gcgcaatcac gaatgaataa cggtttggtt
    11221 gatgcgagtg attttgatga cgagcgtaat ggctggcctg ttgaacaagt ctggaaagaa
    11281 atgcataagc ttttgccatt ctcaccggat tcagtcgtca ctcatggtga tttctcactt
    11341 gataacctta tttttgacga ggggaaatta ataggttgta ttgatgttgg acgagtcgga
    11401 atcgcagacc gataccagga tcttgccatc ctatggaact gcctcggtga gttttctcct
    11461 tcattacaga aacggctttt tcaaaaatat ggtattgata atcctgatat gaataaattg
    11521 cagtttcatt tgatgctcga tgagtttttc taatcagaat tggttaattg gttgtaacac
    11581 tggcagagca ttacgctgac ttgacgggac ggcgcttccc taccctcatg gccgcctccc
    11641 aggaatcgac ccaggtgctt atcgtggaca taatccttta ctcataaatt ggcactgttg
    11701 caaagttagc gatgaggcag ccttttgtct tattcaaagg ccttacattt caaaaactct
    11761 gcttaccagg cgcatttcgc ccaggggatc accataataa aatgctgagg cctggccttt
    11821 gcgtagtgca cgcatcacct caataccttt gatggtggcg taagccgtct tcatggattt
    11881 aaatcccagc gtggcgccga ttatccgttt cagtttgcca tgatcgcatt caatcacgtt
    11941 gttccggtac ttaatctgtc ggtgttcaac gtcagacggg caccggcctt cgcgtttgag
    12001 cagagcaagc gcgcgaccat aggcgggcgc tttatccgtg ttgatgaatc gcgggatctg
    12061 ccacttcttc acgttgttga ggattttacc cagaaaccgg tatgcagctt tgctgttacg
    12121 acgggaggag atataaaaat cgacagtgcg gccccggctg tcgacggccc ggtacagata
    12181 cgcccagcgg ccattgacct tcacgtaggt ttcatccatg tgccacgggc aaagatcgga
    12241 agggttacgc cagtaccagc gcagccgttt ttccatttca ggcgcataac gctgaaccca
    12301 gcggtaaatc gtggagtgat cgacattcac tccgcgttca gccagcatct cctgcagctc
    12361 acggtaactg atgccgtatt tgcagtacca gcgtacggcc cacagaatga tgtcacgctg
    12421 aaaatgccgg cctttgaatg ggttcatgtg cagctccatc agcaaaaggg gatgataagt
    12481 ttatcaccac cgactatttg caacagtgcc catcggcgta gtagtggatg tggtcgatga
    12541 caaagccggt gcgggtcagc gtgcgccgga ggatcggcag aaaatcgacc aggaacgaag
    12601 tagcgcgtgt gacgacggcc ggtacgccga cacgcgccac ggcctcggcc cagcgcgcgg
    12661 ccggcggttg gagcaggccg ttgtgcaccg aaccgtggta ggtgccgacc gccaatgtga
    12721 gccagcgctc tagctcgcgc agcgtcaggg cggccttgtt ttcggaatcg tagtcgccgc
    12781 gctggtcagg gttggagaag gtcgttcccg gcagttcgtc gtgaatcatc tgcatcgccg
    12841 tgccgatgat ccgttccacg atgccgccat agtgcggctg tcccagcggg cgatagtcca
    12901 gccggatgcc atgctgctcg caaccccggc gcagggcctc gctcttgaac tcggccgcgt
    12961 tgtctaggta gagcagcaag ggcttgccgc tcatctgcca atccatttcc acgttcagtc
    13021 cttccagcca agggcgcttg tcgcaggcga catgcacgag gcacaggcca accgaaacgg
    13081 cagacggcgc ttccagcgtg acgaccatgc cgagcacgca gcgggtgaac acgtcgatgg
    13141 cgagggtcag gtacgggcgg ccaataggtt gccggtcgcg gtcatcgacc acgatcaggt
    13201 cgatgaccgt atggtctatc tgcacctgct ccagcggcgc ggtcacggca ggaggctcgc
    13261 cgcccacacc ttgtaggtca cgagcggcat cctggccttc ccgccggcgg atgaccttgc
    13321 gcgggtcaag gctagcgatc cgtaaggcca cggtattgcg cgccggcact cgcagttttt
    13381 gagccttgca cacctgagtg acttcgcggt gaaaggccgc taggctgcgc ttctgcttgg
    13441 tcaggaaccg cttttgcagt agctcgtgga tgacgcgctc gaccggttcc ggcaagcgcc
    13501 ccttaccttt acctccaccg gactggccgg gcaccagatc cgtcacgagg ccgctgcctt
    13561 gccgggcacg ccggatcaga acgtatacct ggcgccgaga caagcccagc gcctgagccg
    13621 ccatatcggc cgcttcgtgc ccgaccgtct ccgactgcgc caacggactg atgatctccg
    13681 cacgacggcg cgcacgctcc caagcctcat caggcagagt ggccacgcct tgttctggaa
    13741 tccgtggggt gtccgtcgcc atgctcacct cgctttggtg cacacgagta ttgagcatag
    13801 tcgagattgg tgcagatcac ttctgatatt gaactgtcag gagctggctg cacaacagcc
    13861 attacgccca atcaactggt gcagtcgtct tctgaaaatg aca
//
