LOCUS       In1395                 33762 bp    DNA     linear   BCT 13-OCT-2020
DEFINITION  Pseudomonas aeruginosa.
ACCESSION
VERSION
KEYWORDS    .
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas
            aeruginosa group; Pseudomonas aeruginosa.
REFERENCE   1  (bases 1 to 33762)
  AUTHORS   Zhou,D.
  TITLE     Compelete sequence of In1395
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33762)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: newbler v. 2.6
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..33762
                     /organism="Pseudomonas aeruginosa"
                     /mol_type="genomic DNA"
     mobile_element  1..33762
                     /gene="In1395"
                     /product="Complex class 1 integron: In1395"
     repeat_region   1..25
                     /gene="IRi_In1395"
                     /product="Inverted repeat at the integrase end of In1395"
     misc_feature    26..1352
                     /gene="5'-CS"
                     /product="5' conserved segment"
     CDS             complement(203..1216)
                     /gene="intI1"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     regulatory      1101..1129
                     /gene="PcH1 (Hybrid 1)"
                     /product="Promoter PcH1 (Hybrid 1)"
     regulatory      1101..1106
                     /gene="-35 region_PcH1 (Hybrid 1)"
                     /product="-35 region of PcH1 (Hybrid 1)"
     regulatory      1124..1129
                     /gene="-10 region_PcH1 (Hybrid 1)"
                     /product="-10 region of PcH1 (Hybrid 1)"
     misc_recomb     1297..1358
                     /gene="attI1"
                     /product="attI1 site"
     CDS             1493..1642
                     /gene="gcu104"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MCTSQITFRATSDTPCAPPVKLGAGIISSVRPGTLTSGSSRSLR
                     SLGPA"
     misc_recomb     1593..1668
                     /gene="attC_gcu104"
                     /product="attC site for gcu104"
     CDS             1734..2954
                     /gene="ereA"
                     /codon_start=1
                     /transl_table=11
                     /product="Erythromycin esterase type I"
                     /translation="MTWRTTRTLLQPQNLDFNEFEILTSVIEGARIVGIGEGAHFVAE
                     FSLARASLIRYLVERHDFNAIGLECGAIQASRLSEWLNSTAGAHELERFSDTLTFSVY
                     GSVLIWLKSYLRESGRKLQLVGIDLPNTLNPRDDLAQLAEIIQLIDHLMKPHVDMLTH
                     LLASIDGQSAVISSAKWGELETARQEKAISGVTRLKLRLASLAPVLKKHVNSDLFRKA
                     SDRIESIEYTLETLRIMKTFFDGTSLEGDTSVRDSYMAGVVDGMVRANPDVKIILLAH
                     NNHLQKTPVSFSGELTAVPMGQHLAERVNYRAIAFTHLGPTVPEMHFPSPDSPLGFSV
                     VTTPADAIREDSMEQYVIDACGTENSCLTLTDAPMEAKRMRSQSASVKTKLSEAFDAI
                     VCVPSAGKDSLVAL"
     misc_recomb     2979..3035
                     /gene="attC_ereA"
                     /product="attC site for ereA"
     CDS             3064..3696
                     /gene="catB3q"
                     /codon_start=1
                     /transl_table=11
                     /product="Chloramphenicol acetyltransferase"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEELAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVEPYAIVGGNPAKK
                     IKKRFTDEEISLLLEMEWWNWSLEKIKAAMPMLCSSNIVGLHKYWLEFAV"
     misc_recomb     3691..3703
                     /gene="attC_catB3q-5'"
                     /product="Truncated attC site for catB3q, 5' fragment"
     mobile_element  complement(3707..5078)
                     /gene="ISPa62"
                     /product="Insertion sequence: ISPa62"
     repeat_region   complement(3707..3722)
                     /gene="IRR_ISPa62"
                     /product="ISPa62 inverted repeat right"
     CDS             complement(3970..5013)
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISPa62 transposase"
                     /translation="MKRIAVDLAKSVYQVAESVRFGQVVQRKRLNREAFRRYIQEQSE
                     PVEWVMEACGTAHYWGRLAQSLGHQVKLLHPRYVRPYRRRNKTDRNDCDAMLEAARCT
                     DIHPVPVKSHDQQQLQQLHGLRETWKKSRTQRINLLRGMLREAGIEAPTSTAAFIRAA
                     SELVDQPELASLSRLLHIVLAEINLYEQCMAECEQQLKRWHADDDIVRKLDEVSGIGL
                     LTASALTAAVGKPERFANGRQLSAWLGMTPREFSSGNSRKLGHISRQGNVYVRTLLIH
                     GSRAALLAAQRCQARTPEKLTQLQRWAVQTAARIGHNKAAVALANKLVRICWAVWCHE
                     RRFSGNWQSVRPA"
     repeat_region   complement(5063..5078)
                     /gene="IRL_ISPa62"
                     /product="ISPa62 inverted repeat left"
     misc_recomb     5084..5132
                     /gene="attC_catB3q-3'"
                     /product="Truncated attC site for catB3q, 3' fragment"
     CDS             5095..5217
                     /gene="gcu161"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MPLRGTAYFRRWTTSALVLLPGKSARCRAPLWTRPRTLPA"
     misc_recomb     5346..5416
                     /gene="attC_gcu161"
                     /product="attC site for gcu161"
     CDS             5420..6211
                     /gene="aadA1a"
                     /codon_start=1
                     /transl_table=11
                     /product="Streptomycin 3'adenylyltransferase"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKP
                     HSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
                     DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPA
                     QYQPVILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_recomb     6213..6226
                     /gene="attC_aadA1a-5'"
                     /product="Truncated attC site for aadA1a, 5' fragment"
     mobile_element  complement(6229..7600)
                     /gene="ISPa62"
                     /product="Insertion sequence: ISPa62"
     repeat_region   complement(6229..6244)
                     /gene="IRR_ISPa62"
                     /product="ISPa62 inverted repeat right"
     CDS             complement(6492..7535)
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISPa62 transposase"
                     /translation="MKRIAVDLAKSVYQVAESVRFGQVVQRKRLNREAFRRYIQEQSE
                     PVEWVMEACGTAHYWGRLAQSLGHQVKLLHPRYVRPYRRRNKTDRNDCDAMLEAARCT
                     DIHPVPVKSHDQQQLQQLHGLRETWKKSRTQRINLLRGMLREAGIEAPTSTAAFIRAA
                     SELVDQPELASLSRLLHIVLAEINLYEQCMAECEQQLKRWHADDDIVRKLDEVSGIGL
                     LTASALTAAVGKPERFANGRQLSAWLGMTPREFSSGNSRKLGHISRQGNVYVRTLLIH
                     GSRAALLAAQRCQARTPEKLTQLQRWAVQTAARIGHNKAAVALANKLVRICWAVWCHE
                     RRFSGNWQSVRPA"
     repeat_region   complement(7585..7600)
                     /gene="IRL_ISPa62"
                     /product="ISPa62 inverted repeat left"
     misc_recomb     7608..7654
                     /gene="attC_aadA1a-3'"
                     /product="Truncated attC site for aadA1a, 3' fragment"
     misc_feature    7649..8961
                     /gene="3'-CS1"
                     /product="First copy of 3' conserved segment"
     CDS             7757..8104
                     /gene="qacED1"
                     /codon_start=1
                     /transl_table=11
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             8098..8937
                     /gene="sul1"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITISETLAKFRSRDARDRGL
                     DHA"
     mobile_element  complement(8962..9085)
                     /gene="truncated ISCR1-3'"
                     /product="Insertion sequence: truncated ISCR1, 3'
                     fragment"
     mobile_element  complement(9085..10886)
                     /gene="Tn4662b remnant"
                     /product="Unit transposon: Tn4662b remnant"
     repeat_region   complement(9085..9122)
                     /gene="IRR_Tn4662b"
                     /product="Tn4662b inverted repeat right"
     CDS             complement(9125..9496)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MNLSTIEALAIAWARIAEEAELPAGYEGTATPEAHRACEVIQER
                     IREHVVATNDMRLFGLLHLLGQASLRMEQALWPEEYARMTRVVEEALREADDPNAKSY
                     THEEVMRAMQELIDQARDKPC"
     CDS             complement(9493..9819)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MSRSRRKTPIVGHTTCRSEREDKKLWHQRWRTHERTALASASPE
                     ALCAHLPLLENQVSNVWSMGKDGRSYWPIKRQAATADRIANHKGRNPQERASLKKRLL
                     RKWMSK"
     CDS             complement(9843..10178)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MAARITDDEWDELTPENFDTTALLRAVDAVDVLRGDLNDSADGA
                     PPQLRTDLLKLHQLAMAAFNEGSRSRVAELFDLAVDLQDQVDHLMTSLEQVQETLSRL
                     TALYPESLS"
     CDS             complement(10193..10528)
                     /gene="relB"
                     /codon_start=1
                     /transl_table=11
                     /product="Antitoxin RelB"
                     /translation="MQKRIIEGVEVQRSSGNVFADLGLPDAEKLKIKTGLVVEIRRAM
                     RALGLTQQAAAKRMGIPQPKVSGMMRGDFTNLSERKLMDCLNRLGYDIEIKVRPAAEP
                     IGHLTLATA"
     CDS             complement(10509..10886)
                     /gene="relE"
                     /codon_start=1
                     /transl_table=11
                     /product="Toxin RelE"
                     /translation="MTNKEKPLEWIASSHKDLMALPSDVRRRFGYALSLAQIGDQDDA
                     AKVLKGFGGAGVLEVVEDDAGGTYRAVYTVKFAEAVFVLHCFQKKSKSGIATPKADMD
                     IIRARLKVAEVLAQELRNAKTNH"
     mobile_element  complement(10883..12886)
                     /gene="truncated IScs605"
                     /product="Insertion sequence: truncated IScs605"
     misc_feature    complement(10883..12319)
                     /gene="truncated tnpA"
                     /product="Truncated IScs605 transposase"
     repeat_region   complement(12871..12886)
                     /gene="IRL_IScs605"
                     /product="IScs605 inverted repeat left"
     CDS             12932..14407
                     /gene="msr(E)"
                     /codon_start=1
                     /transl_table=11
                     /product="Macrolide efflux protein Msr(E)"
                     /translation="MSLIIKARNIRLDYAGRDVLDIDELEIHSYDRIGLVGDNGAGKS
                     SLLKVLNGEIVLAEATLQRFGDFAHISQLGGIEIETVEDRAMLSRLGVSNVQNDTMSG
                     GEETRAKIAAAFSQQVHGILADEPTSHLDLNGIDLLIGQLKAFDGALLVISHDRYFLD
                     MVVDKIWELKDGKITEYWGGYSDYLRQKEEERQHQAVEYELMMKERERLESAVQEKRQ
                     QANRLDNKKKGEKSKNSTESAGRLGHAKMTGTKQRKLYQAAKSMEKRLAALEDIQAPE
                     HLRSIRFRQSSALELHNKFPITADGLSLKFGSRTIFDDANFIIPLGAKVAITGSNGTG
                     KTSLLKMISERADGLTISPKAEIGYFTQTGYKFNTHKSVLSFMQEECEYTVAEIRAVL
                     ASMGIGANDIQKNLSDLSGGEIIKLLLSKMLLGKYNILLMDEPGNYLDLKSIAALETM
                     MKSYAGTIIFVSHDKQLVDNIADIIYEIKDHKIIKTFERDC"
     CDS             14463..15347
                     /gene="mph(E)"
                     /codon_start=1
                     /transl_table=11
                     /product="Macrolide 2'-phosphotransferase Mph(E)"
                     /translation="MTIQDIQSLAEAHGLLLTDKMNFNEMGIDFKVVFALDTKGQQWL
                     LRIPRRDGMREQIKKEKRILELVKKHLSVEVPDWRISSTELVAYPILKDNPVLNLDAE
                     TYEIIWNMDKDSPKYITSLAKTLFEIHSIPEKEVRENDLKIMKPSDLRPEIANNLQLV
                     KSEIGISEQLETRYRKWLDNDVLWADFTQFIHGDLYAGHVLASKDGAVSGVIDWSTAH
                     IDDPAIDFAGHVTLFGEESLKTLIIEYEKLGGKVWNKLYEQTLERAAASPLMYGLFAL
                     ETQNESLIVGAKAQLGVI"
     mobile_element  complement(15424..21064)
                     /gene="Tn4662b"
                     /product="Unit transposon: Tn4662b"
     repeat_region   complement(15424..15461)
                     /gene="IRR_Tn4662b"
                     /product="Tn4662b inverted repeat right"
     CDS             complement(15464..15835)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MNLSTIEALAIAWARIAEEAELPAGYEGTATPEAHRACEVIQER
                     IREHVVATNDMRLFGLLHLLGQASLRMEQALWPEEYARMTRVVEEALREADDPNAKSY
                     THEEVMRAMQELIDQARDKPC"
     CDS             complement(15832..16158)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MSRSRRKTPIVGHTTCRSEREDKKLWHQRWRTHERTALASASPE
                     ALCAHLPLLENQVSNVWSMGKDGRSYWPIKRQAATADRIANHKGRNPQERASLKKRLL
                     RKWMSK"
     CDS             complement(16182..16517)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MAARITDDEWDELTPENFDTTALLRAVDAVDVLRGDLNDSADGA
                     PPQLRTDLLKLHQLAMAAFNEGSRSRVAELFDLAVDLQDQVDHLMTSLEQVQETLSRL
                     TALYPESLS"
     CDS             complement(16532..16867)
                     /gene="relB"
                     /codon_start=1
                     /transl_table=11
                     /product="Antitoxin RelB"
                     /translation="MQKRIIEGVEVQRSSGNVFADLGLPDAEKLKIKTGLVVEIRRAM
                     RALGLTQQAAAKRMGIPQPKVSGMMRGDFTNLSERKLMDCLNRLGYDIEIKVRPAAEP
                     IGHLTLATA"
     CDS             complement(16848..17225)
                     /gene="relE"
                     /codon_start=1
                     /transl_table=11
                     /product="Toxin RelE"
                     /translation="MTNKEKPLEWIASSHKDLMALPSDVRRRFGYALSLAQIGDQDDA
                     AKVLKGFGGAGVLEVVEDDAGGTYRAVYTVKFAEAVFVLHCFQKKSKSGIATPKADMD
                     IIRARLKVAEVLAQELRNAKTNH"
     misc_recomb     complement(17281..17392)
                     /gene="res"
                     /product="Resolution site"
     CDS             17384..18019
                     /gene="tnpR"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn4662b resolvase"
                     /translation="MRKPVFDGYPPMLVGYMRVSSDSDRQSTDLQRDALLAAGVDPRH
                     LFEDRASGAKDDRAGLARALEFVRAGDVLVVWKLDRLGRSLSHLLAIVTSLKDKRVAF
                     RSLTENLDTTTPSGEFLFQVFGALAQYERALIQERVVAGLAAARKRGRIGGRPQAITG
                     EKLDAIVAALDGGMSKAAVCRNFNVKRTTLIETLTRAGWRGAGRTVDEQQE"
     CDS             18003..21032
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn4662b transposase"
                     /translation="MSNKNKLLTVFSDAEQEALYGLPDFDDAQRLEYLALTESELAFA
                     SSRPSLQAQVYCVLQIGYFKAKHAFFRFDWHEVEDDCAFVLSRYFHGEAFERKAITKH
                     EHYSQRGQIAELFGYRSWAASFLPQLAQQAEQIVRRDVMPGFVAAELIVWLSEHKIIR
                     PGHTTLQELVSEALSTERRRLGGLLAEVLDESAKAALGQLLVRDDTLSQLAALKQDAK
                     DFGWRQMAGEREKRATLKSLHGIAKALLPKLGISQQNLLYYASLANFYTVHDLRHLKA
                     EQTRLYLLCYAWVRYRQLTDNLVDAMAFHMKKLEDESRTGAKQSFVAEQLRRHQETPQ
                     VGRLLSLYVDDSVADPTPFGEVRQRAYKIMSRELLQNTAQRMSVKPLNKLALHWQAVD
                     GLAERIRRHLRPLYVALDFAGTAPDNPWLAALTWAKSVFAKQQRLSQRPLDECPAATL
                     PKRLRPYLLMFDAEGTPTGLHADRYEFWLYRQVRKRFQAGELYIDDSLQHRHLSDELV
                     SMDEKAAVLAQMDIPFLRQPVSAQLDALAAELRAQWVAFNRELKQGKLTHLEYDKDTQ
                     RLTWRKPKGENQKAREQALYEQLPYCDVADVFRFVNGQCQFLSALTPLQPRYAKKVAD
                     ADSLMAVIIAQAMNHGNQVMARTSDIPYHVLESTYQQYLRQATLHVANDCISNAIAAL
                     PIFPHYSFDLDSLYGAVDGQKFGVERPTVKARYSRKYFGRGKGVVAYTLLCNHVPLNG
                     YLIGAHEYEAHHVFDIWYRNTSDIVPSAITGDMHSINKANFAILHWFGLRFEPRFTDL
                     DDQLQELYCADDLALYEKCLIRPAGQIDRQLIVGEKANIDRIVATLGLKEMTQGTLIR
                     KLCTYTAPNPTRRAIFEFDKLIRSIYTLRYLRDPQLERNVHRSQNRIESYHQLRSTIA
                     QVGGKKELTGRTDIEIEISNQCARLIGNAIIFYNSAILSLLLTKYEAAGNAKALALIT
                     QMSPAAWRHILLNGHYTFQTDGKFIDLDALVAGLELG"
     repeat_region   complement(21027..21064)
                     /gene="IRL_Tn4662b"
                     /product="Tn4662b inverted repeat left"
     mobile_element  complement(21065..23100)
                     /gene="truncated ISCR1-5'"
                     /product="Insertion sequence: truncated ISCR1, 5'
                     fragment"
     CDS             21327..22868
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     repeat_region   23080..23100
                     /gene="oriIS"
                     /product="oriIS of ISCR1"
     CDS             23131..23787
                     /gene="qnrVC6"
                     /codon_start=1
                     /transl_table=11
                     /product="Fluoroquinolone resistance protein"
                     /translation="MEKSKQLYNQVNFSHQDLQEHIFSNCTFIHCNFKRSNLRDTQFI
                     NCTFIEQGALEGCDFSYADLRDASFKDCQLSMSHFKGANCFGIELRDCDLKGANFSQV
                     SFVNQVSNKMYFCSAYITGCNLSYANFEQQLIEKCDLFENRWIGANLRGASFKESDLS
                     RGVFSEDCWEQFRVQGCDLSHSELYGLDPRKIDLTGVKICSWQQEQLLEQLGVIIVPD
                     "
     CDS             23958..24248
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MDFIWLVLVLGSAAAFYYFVSYSKPQDDDWHKLPTLEDYLIKHP
                     ECKTADSESAKCFSCGSDKVIFQPLTAHADHRYKHICLSCKKTLFRSKAIMS"
     mobile_element  complement(24623..26741)
                     /gene="truncated ISCR1"
                     /product="Insertion sequence: truncated ISCR1"
     CDS             24968..26509
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     repeat_region   26721..26741
                     /gene="oriIS"
                     /product="oriIS of ISCR1"
     CDS             26911..27159
                     /gene="fepC"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type cobalamin/Fe3+-siderophores transport
                     system"
                     /translation="MRTLACHGRTVVMVLHDLASACRYADHLIAMRDGQIVDQGAPAD
                     VVTPALVRALYQVECTLLLDPDTGSPLLANVRRAERSE"
     CDS             27223..29058
                     /gene="mdlB"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC MDR transporter/ATP-binding cassette (ABC)
                     transporters"
                     /translation="MASSTPSSSASSANQSFQALVRLLRYAKGYRRRITAATICSIIN
                     KLFDIAPEILIGVAIDVVVNQENSFVARLGFETPHEQIAILAVLTFFIWAGESLFEYL
                     YQVLWRNLAQRLQADLRQDAYEHAQRLDMAFFESKSSGQLVATMNDDVNQLERFLDGG
                     ANALIQVGVTVVAVGAVFFVLSPLIALLAFTPIPLIIWGAFFFQRKAGPLYSEVREKV
                     GDLSSRLSNNLSGIATIKSFTSEAREAERLRSASEAYVDANRQAIRVSSAFIPVIRMA
                     ILAGFLATFTVGGMMALNGSLNVGAYGVLVFLTQRLLWPLTGLAQVIDLFERAMASTK
                     RILDLLEVPITVKDDSTQALAAPVKGEVRFEAVSFQYEASQVGVNAVDLHVPAGTTLA
                     LVGATGSGKSTLIKLLLRFYDPASGRVLVDGQPITEVSMHSLRQAIGLVSQDVYLFEG
                     SIRDNIAYGMPDADEAAIIEAAKTAEAWSFIETLPQGLDTPVGERGVRLSGGQRQRLS
                     LARALLKDPPILVLDEATSAVDNETEAAIQRSLKRIAHGRTVIMIAHRLSTIVHADEI
                     VVIEKGQVAERGSHASLLQADGHYAAQWRVQTGAAQAGDVEVLGR"
     CDS             complement(29109..29684)
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MKALIALFPLLLALPVQADWQLDPAQSQVRASITQLDGSAPQTH
                     HHHVSNLQGDISPDGTLRLPLRLSQTDVLQRLGDLPPWVGLLANTPLVTLVAQMPPER
                     LDRLDMGEELVETLTFRVQTDRLTQEEAVPLRFTRVGLNEVRVTHAEPMALDGNALMA
                     NSTLRTVLSLLGYQQIDEHVPVTLNALLVNR"
     CDS             29816..30349
                     /gene="folA"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydrofolate reductas"
                     /translation="MHKPTPLKRLSMILARDLNGAIGYEGSLAIKSDNDFAWYKKITK
                     PFKHAVCGRVTYEEDLPDIVKKRHRFIIITRNPDKYASTPEAQYMTLSDALKELQVWD
                     VPGHDIICLGGAEIYKALLPYVSTVYLTTFFSVADEADTYFNDFTDKWESVGATWFND
                     CYCTRLERVCQSTNNII"
     misc_feature    30439..32607
                     /gene="3'-CS2"
                     /product="Second copy of 3' conserved segment"
     CDS             30477..30824
                     /gene="qacED1"
                     /codon_start=1
                     /transl_table=11
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             30818..31657
                     /gene="sul1"
                     /codon_start=1
                     /transl_table=11
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     CDS             31785..32285
                     /gene="orf5"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHA
                     GRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAE
                     RLELEI"
     CDS             32309..32596
                     /gene="orf6"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MSGWDGPVASRSLAVRPRCLGCARGCRYPPLPSSTLDNAAAVIA
                     ADARAGLFGPVRLARPSACLGEISGGRINGGASPPFVRVKAEDSSLKNIRL"
     repeat_region   complement(32608..32632)
                     /gene="IRt_In1395"
                     /product="Inverted repeat at the tni end of In1395"
     mobile_element  32731..33610
                     /gene="IS6100"
                     /product="Insertion sequence: IS6100"
     repeat_region   32731..32744
                     /gene="IRL_IS6100"
                     /product="IS6100 inverted repeat left"
     CDS             32792..33556
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6100 transposase"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     repeat_region   33597..33610
                     /gene="IRR_IS6100"
                     /product="IS6100 inverted repeat right"
     repeat_region   33738..33762
                     /gene="IRt_In1395"
                     /product="Inverted repeat at the tni end of In1395"
BASE COUNT     7619 a   9187 c   9240 g   7716 t
ORIGIN
        1 tgtcgttttc agaagacggc tgcactgaac gtcagaagcc gactgcacta tagcagcgga
       61 ggggttggat ccatcaggca acgacgggct gctgccggcc atcagcggac gcagggagga
      121 ctttccgcaa ccggccgttc gatgcggcac cgatggcctt cgcgcagggg tagtgaatcc
      181 gccaggattg acttgcgctg ccctacctct cactagtgag gggcggcagc gcatcaagcg
      241 gtgagcgcac tccggcaccg ccaactttca gcacatgcgt gtaaatcatc gtcgtagaga
      301 cgtcggaatg gccgagcaga tcctgcacgg ttcgaatgtc gtaaccgctg cggagcaagg
      361 ccgtcgcgaa cgagtggcgg agggtgtgcg gtgtggcggg cttcgtgatg cctgcttgtt
      421 ctacggcacg tttgaaggcg cgctgaaagg tctggtcata catgtgatgg cgacgcacga
      481 caccgctccg tggatcggtc gaatgcgtgt gctgcgcaaa aacccagaac cacggccagg
      541 aatgcccggc gcgcggatac ttccgctcaa gggcgtcggg aagcgcaacg ccgctgcggc
      601 cctcggcctg gtccttcagc caccatgccc gtgcacgcga cagctgctcg cgcaggctgg
      661 gtgccaagct ctcgggtaac atcaaggccc gatccttgga gcccttgccc tcccgcacga
      721 tgatcgtgcc gtgatcgaaa tccagatcct tgacccgcag ttgcaaaccc tcactgatcc
      781 gcatgcccgt tccatacaga agctgggcga acaaacgatg ctcgccttcc agaaaaccga
      841 ggatgcgaac cacttcatcc ggggtcagca ccaccggcaa gcgccgcgac ggccgaggtc
      901 ttccgatctc ctgaagccag ggcagatccg tgcacagcac cttgccgtag aagaacagca
      961 aggccgccaa tgcctgacga tgcgtggaga ccgaaacctt gcgctcgttc gccagccagg
     1021 acagaaatgc ctcgacttcg ctgctgccca aggttgccgg gtgacgcaca ccgtggaaac
     1081 ggatgaaggc acgaacccag tggacataag cctgttcggt tcgtaagctg taatgcaagt
     1141 agcgtatgcg ctcacgcaac tggtccagaa ccttgaccga acgcagcggt ggtaacggcg
     1201 cagtggcggt tttcatggct tgttatgact gtttttttgt acagtctatg cctcgggcat
     1261 ccaagcagca agcgcgttac gccgtgggtc gatgtttgat gttatggagc agcaacgatg
     1321 ttacgcagca gggcagtcgc cctaaaacaa agttagaggc aaaggcaaaa ttggttgttc
     1381 ggcaccgtgc caggaaacac aatcaccgca tcatcgcggc gctcctgaat cgaatggtcg
     1441 ccggacagta gaggccgtta tttgtggcca gcaaaggagt tgcgttcaga aaatgtgcac
     1501 atcacaaata accttccggg ctacatccga cacgccgtgc gctccgccgg tcaagctcgg
     1561 tgcaggcatc atttccagcg tccggccggg cactctaact agtggctcaa gtcgttcgct
     1621 tcgctcactg ggaccggctt aagccggccc cttagccaaa cgttatgctg tgacccgggt
     1681 tgttggcgaa gcgaacgtat ggcgattaaa gtaataaacg caaaggtaaa ataatgacat
     1741 ggagaacgac cagaacactt ttacagcctc aaaatctgga cttcaatgag tttgagattc
     1801 ttacttccgt aattgagggc gcccgaattg tcggcattgg cgagggcgct cattttgtcg
     1861 cggagttttc actggctaga gcaagtctta tccgctattt ggtcgaaagg catgatttta
     1921 atgcgattgg tttggaatgt ggggcgattc aggcatcccg gttatctgaa tggctcaact
     1981 caacagccgg tgctcatgaa cttgagcgat tttcggatac cctgaccttt tctgtgtatg
     2041 gctcagtgct gatctggctg aaatcatatc tccgcgaatc aggaagaaaa ctgcagttag
     2101 tcggaatcga cttacccaac accctgaacc caagggacga cctagcgcaa ttggccgaaa
     2161 ttatccagct catcgatcac ctcatgaaac cgcacgttga tatgctgact cacttgttgg
     2221 cgtccattga tggccagtcg gcggttattt catcggcaaa atggggggag ctagaaacgg
     2281 ctcggcagga gaaagctatc tcaggggtaa ccagattgaa gctccgcttg gcgtcgcttg
     2341 cccctgtact gaaaaaacac gtcaacagcg atttgttccg aaaagcctct gatcgaatag
     2401 agtcgataga gtatacgttg gaaaccttgc gtataatgaa aactttcttc gatggtacct
     2461 ctcttgaggg agatacttcc gtacgtgact cgtatatggc gggcgtagta gatggaatgg
     2521 ttcgagcgaa tccggatgtg aagataattc tgctggcgca caacaatcat ttacaaaaaa
     2581 ccccagtctc cttttcaggc gagcttacgg ctgttcccat ggggcagcac ctcgcagaga
     2641 gggtgaatta ccgtgcgatt gcattcaccc atcttggacc caccgtgccg gaaatgcatt
     2701 tcccatcgcc cgacagtcct cttggattct ctgttgtgac cacgcctgcc gatgcaatcc
     2761 gtgaggatag tatggaacag tatgtcatcg acgcctgtgg tacggagaat tcatgtctga
     2821 cattgacaga tgcccccatg gaagcaaagc gaatgcggtc tcaaagcgcc tctgtaaaaa
     2881 cgaaattgag cgaggcattt gatgccatcg tctgtgttcc aagcgccggc aaggacagcc
     2941 tagttgccct ataggaaacc ggaaatgaaa atgagggagc ataacctgcg aatccaccgg
     3001 acggttttca accgccggtg atcagcgcgt tagacggcaa agtcacagac cgcgggatct
     3061 cttatgacca actactttga tagccccttc aaaggcaagc tgctttctga gcaagtgaag
     3121 aaccccaata tcaaagttgg gcggtacagc tattactctg gctactatca tgggcactca
     3181 ttcgatgact gcgcacggta tctgtttccg gaccgtgatg acgttgataa gttgatcatc
     3241 ggtagtttct gctctatcgg gagtggggct tcctttatca tggctggcaa tcaggggcat
     3301 cggtacgact gggcatcatc tttcccgttc ttttatatgc aggaagaact tgcattctca
     3361 agcgcactcg atgccttcca aaaagcaggt aatactgtca ttggcaatga cgtttggatc
     3421 ggctctgagg caatggtcat gcccggaatc aagatcgggc acggtgcggt gataggcagc
     3481 cgctcgttgg tgacaaaaga tgtggagcct tacgctatcg ttggcggcaa tcccgctaag
     3541 aagattaaga aacgcttcac cgatgaggaa atttcattgc ttctggagat ggagtggtgg
     3601 aattggtcac tggagaagat caaagcggca atgcccatgc tgtgctcgtc taatattgtt
     3661 ggcctgcaca agtattggct cgagtttgcc gtctaacaat tcatatatgg actctcccca
     3721 caagcagtga gcaaagcttt gcttttgcac ctgtcgtcag cgcggttgca ttcgtatatc
     3781 cggcctgttg tggacgttca agccctggcc attctgtagt tcgcgcagcg ggggccaagc
     3841 gttcaatcga tcacggggat catcattgtt atcggccttg ctccgctgca ggactcgcct
     3901 gttccgacag tgctgctgct caccacaacc acaagaaaac catcacccct ttactgatta
     3961 cccccgccgt caggcgggcc taacgctttg ccaattgcca ctgaaccgcc gctcgtggca
     4021 ccacaccgcc cagcagatcc gcaccagctt gttggccagt gctaccgccg ctttgttgtg
     4081 accgatacgc gccgccgtct gcacagccca gcgctgtaac tgcgtcagct tttccggcgt
     4141 tcgagcctgg cagcgttgtg cggcgagcaa ggctgcacgt gagccgtgga tcagtaacgt
     4201 gcgcacatag acattgccct gccggctgat atggccgagc ttgcggctat tgccactgct
     4261 gaactcacgc ggcgtcatac ccagccaggc gctgagctgg cgaccattgg caaagcgttc
     4321 gggcttgccg acagcggcgg tcagggcgct ggcggttagc aggccaatgc cactgacttc
     4381 atccagtttg cgcacgatgt catcatcagc atgccagcgc ttgagttgct gttcgcattc
     4441 agccatgcac tgttcgtaca agttgatctc ggccaggacg atatgcagca ggcggctcaa
     4501 ggaagcgagt tcaggttggt ctacaagttc actggcagct cggatgaagg ctgcggtcga
     4561 cgttggggct tcgatacccg cttcacgcag catgccgcgc agcaggttga tgcgctgggt
     4621 gcggctcttc ttccaggttt cacgtagccc gtgcaattgc tggagctgtt gttgatcgtg
     4681 gctcttcacc ggcacgggat gaatgtcggt gcagcgcgcc gcttcgagca tggcatcgca
     4741 gtcattacgg tcggttttgt tacgacggcg atagggccgc acgtagcgcg ggtgcagcag
     4801 cttcacctga tgaccgagcg attgcgccaa ccgcccccag taatgcgctg taccacaggc
     4861 ctccatcacc cactcgaccg gctcggactg ctcctgtata tatcgccgga acgcctctcg
     4921 gttcagccgc ttgcgctgca ccacctggcc gaaacggaca ctctcggcaa cttggtaaac
     4981 ggacttggcc agatcaacgg caatgcgctt cataacgact ctcccgctca gaaaacctcg
     5041 acaccttggt atagaactgt ggtgtgggga gagtccatta cagcaatcaa gccgatgccg
     5101 cttcgcggca cggcttattt caggcgttgg acgaccagtg ctctagtgct gctgccgggt
     5161 aaatctgcac gctgccgcgc tccgttgtgg actcgaccgc gtacccttcc ggcgtgagca
     5221 tcgtggagta ccagccgacg atggttccgt gccacatcga gcccttcgtt ttgcgcacgg
     5281 tctgaccgtg cttgaatttc gtatgagttt ccgggtacag catttgcatc tccttcaagc
     5341 gttacgccca actatttaat cgagcgcgac ccgctacagc tgcgctttcg ctggcggctc
     5401 atttcggtcg ttaaacatca tgagggaagc ggtgatcgcc gaagtatcga ctcaactatc
     5461 agaggtagtt ggcgtcatcg agcgccatct cgaaccgacg ttgctggccg tacatttgta
     5521 cggctccgca gtggatggcg gcctgaagcc acacagtgat attgatttgc tggttacggt
     5581 gaccgtaagg cttgatgaaa caacgcggcg agctttgatc aacgaccttt tggaaacttc
     5641 ggcttcccct ggagagagcg agattctccg cgctgtagaa gtcaccattg ttgtgcacga
     5701 cgacatcatt ccgtggcgtt atccagctaa gcgcgaactg caatttggag aatggcagcg
     5761 caatgacatt cttgcaggta tcttcgagcc agccacgatc gacattgatc tggctatctt
     5821 gctgacaaaa gcaagagaac atagcgttgc cttggtaggt ccagcggcgg aggaactctt
     5881 tgatccggtt cctgaacagg atctatttga ggcgctaaat gaaaccttaa cgctatggaa
     5941 ctcgccgccc gactgggctg gcgatgagcg aaatgtagtg cttacgttgt cccgcatttg
     6001 gtacagcgca gtaaccggca aaatcgcgcc gaaggatgtc gctgccgact gggcaatgga
     6061 gcgcctgccg gcccagtatc agcccgtcat acttgaagct agacaggctt atcttggaca
     6121 agaagaagat cgcttggcct cccgcgcaga tcagttggaa gaatttgttc actacgtgaa
     6181 aggcgagatc accaaggtag tcggcaaata atgtctaaca attcgtatat ggactctccc
     6241 cacaagcagt gagcaaagct ttgcttttgc acctgtcgtc agcgcggttg cattcgtata
     6301 tccggcctgt tgtggacgtt caagccctgg ccattctgta gttcgcgcag cgggggccaa
     6361 gcgttcaatc gatcacgggg atcatcattg ttatcggcct tgctccgctg caggactcgc
     6421 ctgttccgac agtgctgctg ctcaccacaa ccacaagaaa accatcaccc ctttactgat
     6481 tacccccgcc gtcaggcggg cctaacgctt tgccaattgc cactgaaccg ccgctcgtgg
     6541 caccacaccg cccagcagat ccgcaccagc ttgttggcca gtgctaccgc cgctttgttg
     6601 tgaccgatac gcgccgccgt ctgcacagcc cagcgctgta actgcgtcag cttttccggc
     6661 gttcgagcct ggcagcgttg tgcggcgagc aaggctgcac gtgagccgtg gatcagtaac
     6721 gtgcgcacat agacattgcc ctgccggctg atatggccga gcttgcggct attgccactg
     6781 ctgaactcac gcggcgtcat acccagccag gcgctgagct ggcgaccatt ggcaaagcgt
     6841 tcgggcttgc cgacagcggc ggtcagggcg ctggcggtta gcaggccaat gccactgact
     6901 tcatccagtt tgcgcacgat gtcatcatca gcatgccagc gcttgagttg ctgttcgcat
     6961 tcagccatgc actgttcgta caagttgatc tcggccagga cgatatgcag caggcggctc
     7021 aaggaagcga gttcaggttg gtctacaagt tcactggcag ctcggatgaa ggctgcggtc
     7081 gacgttgggg cttcgatacc cgcttcacgc agcatgccgc gcagcaggtt gatgcgctgg
     7141 gtgcggctct tcttccaggt ttcacgtagc ccgtgcaatt gctggagctg ttgttgatcg
     7201 tggctcttca ccggcacggg atgaatgtcg gtgcagcgcg ccgcttcgag catggcatcg
     7261 cagtcattac ggtcggtttt gttacgacgg cgatagggcc gcacgtagcg cgggtgcagc
     7321 agcttcacct gatgaccgag cgattgcgcc aaccgccccc agtaatgcgc tgtaccacag
     7381 gcctccatca cccactcgac cggctcggac tgctcctgta tatatcgccg gaacgcctct
     7441 cggttcagcc gcttgcgctg caccacctgg ccgaaacgga cactctcggc aacttggtaa
     7501 acggacttgg ccagatcaac ggcaatgcgc ttcataacga ctctcccgct cagaaaacct
     7561 cgacaccttg gtatagaact gtggtgtggg gagagtccat tacagcattc aagccgacgc
     7621 cgcttcgcgg cgcggcttaa ctcaagcgtt agatgcacta agcacataat tgctcacagc
     7681 caaactatca ggtcaagtct gcttttatta tttttaagcg tgcataataa gccctacaca
     7741 aattgggaga tatatcatga aaggctggct ttttcttgtt atcgcaatag ttggcgaagt
     7801 aatcgcaaca tccgcattaa aatctagcga gggctttact aagcttgccc cttccgccgt
     7861 tgtcataatc ggttatggca tcgcatttta ttttctttct ctggttctga aatccatccc
     7921 tgtcggtgtt gcttatgcag tctggtcggg actcggcgtc gtcataatta cagccattgc
     7981 ctggttgctt catgggcaaa agcttgatgc gtggggcttt gtaggtatgg ggctcataat
     8041 tgctgccttt ttgctcgccc gatccccatc gtggaagtcg ctgcggaggc cgacgccatg
     8101 gtgacggtgt tcggcattct gaatctcacc gaggactcct tcttcgatga gagccggcgg
     8161 ctagaccccg ccggcgctgt caccgcggcg atcgaaatgc tgcgagtcgg atcagacgtc
     8221 gtggatgtcg gaccggccgc cagccatccg gacgcgaggc ctgtatcgcc ggccgatgag
     8281 atcagacgta ttgcgccgct cttagacgcc ctgtccgatc agatgcaccg tgtttcaatc
     8341 gacagcttcc aaccggaaac ccagcgctat gcgctcaagc gcggcgtggg ctacctgaac
     8401 gatatccaag gatttcctga ccctgcgctc tatcccgata ttgctgaggc ggactgcagg
     8461 ctggtggtta tgcactcagc gcagcgggat ggcatcgcca cccgcaccgg tcaccttcga
     8521 cccgaagacg cgctcgacga gattgtgcgg ttcttcgagg cgcgggtttc cgccttgcga
     8581 cggagcgggg tcgctgccga ccggctcatc ctcgatccgg ggatgggatt tttcttgagc
     8641 cccgcaccgg aaacatcgct gcacgtgctg tcgaaccttc aaaagctgaa gtcggcgttg
     8701 gggcttccgc tattggtctc ggtgtcgcgg aaatccttct tgggcgccac cgttggcctt
     8761 cctgtaaagg atctgggtcc agcgagcctt gcggcggaac ttcacgcgat cggcaatggc
     8821 gctgactacg tccgcaccca cgcgcctgga gatctgcgaa gcgcaatcac catctcggaa
     8881 accctcgcga aatttcgcag tcgcgacgcc agagaccgag ggttagatca tgcctagcat
     8941 tcaccttccg gccgcccgct aaatatctcc ttttgggttg ttaataaaac atccaataag
     9001 ttgactgtgc gtgaaaaaga aagttttgtg tgatggcgtt gaagatcgca ccgttaagct
     9061 cttatgtggg atggtgcaga gctcggggtt gtaagccgga aacccagaaa tttccgtcag
     9121 ccgatcaaca tggcttgtct cgcgcttggt cgatgagttc ctgcatcgcc cgcatgactt
     9181 cttcgtgggt gtacgacttg gcgttggggt cgtcggcctc tcggagagct tcctcgacca
     9241 cgcgggtcat ccgcgcatat tcttccggcc acagcgcttg ctccatgcgc agcgacgcct
     9301 gcccaagcag gtgcagcagg ccgaacagcc gcatgtcatt ggtggcgacg acgtgctctc
     9361 gaatccgctc ctggatcacc tcgcaggccc gatgcgcctc tggcgtcgcc gtgccctcgt
     9421 agccggctgg gagttctgct tcttcagcga ttcgcgccca agcgatagcc agcgcctcga
     9481 tggtggacag gttcatttgc tcatccactt gcgcagcaga cgctttttca gggaggcgcg
     9541 ctcttgcgga ttgcgtccct tgtggttggc aatgcgatcc gccgtggcgg cctggcgctt
     9601 gatgggccag taggagcggc catccttacc catcgaccag acgttgctga cctggttttc
     9661 cagtagaggc agatgggcgc atagagcttc cggcgacgcg ctggccagcg cggtgcgctc
     9721 gtgagttcgc cagcgctgat gccagagttt cttgtcctcg cgctcgctac ggcaggtcgt
     9781 gtgcccaacg atgggcgttt tgcggcggct gcggctcatg atgtggttgt ctccaagaac
     9841 attcaggaca ggctttctgg gtagagcgcc gtcaaccggg acagggtttc ttgcacttgt
     9901 tccagcgagg tcatcagatg atcaacctga tcctgaagat ccacggcgag atcaaatagc
     9961 tcagccactc ggctgcgtga tccctcgttg aacgcggcca ttgccagttg atgcagcttc
    10021 aacaggtcgg tgcgcagttg cggaggtgcg ccgtctgcgc tgtcattcaa atcgccgcgc
    10081 agcacgtcca cggcatcgac tgcacgcagc agtgccgtgg tatcgaaatt ctcgggagtc
    10141 agttcgtccc attcgtcgtc ggtgatgcgg gctgccatca ggagggctcc gattaagcgg
    10201 ttgcgagcgt tagatgcccg atcggctcgg ctgctggccg taccttgatt tcgatgtcgt
    10261 agccgaggcg attcagacaa tccatcagct tgcgttcgga tagattggtg aagtcgccgc
    10321 gcatcatgcc cgacaccttc ggttgcggga tgcccatgcg tttggccgcc gcttgttgag
    10381 tcagcccaag ggcgcgcatg gccctcctga tctcgaccac caggccggtc ttgatcttga
    10441 gcttttcagc gtcaggcagt ccaaggtcgg caaagacgtt gcccgagctg cgctgaacct
    10501 cgacgccttc aatgattcgt ttttgcattt cgtagctcct gtgccaatac ctcggccacc
    10561 ttcagccgag cgcggatgat gtccatgtcg gcctttggcg tggcgattcc gctcttgctc
    10621 ttcttctgga agcagtgcag gacgaacacc gcttccgcaa acttgaccgt gtataccgct
    10681 cgataggtgc cgccggcatc gtcttcgacg acctccagca cgccggcacc accgaacccc
    10741 ttgagcacct ttgctgcgtc atcctgatcg cctatctgcg ccaacgagag cgcgtaaccg
    10801 aaacggcgac gcacgtcgga cggcaacgcc atcaaatcct tgtggctgct cgcgatccat
    10861 tcgagcggtt tttctttgtt tgtcatgacg gaattttata cctgttcagg taatgatgta
    10921 aacgcggcaa cctcaaggag gtgtcgtaaa acatttcttt tttgacgctt cgttgagcac
    10981 tgctggttga gcttttggct cggccagtct tacgattgcc tccacgtcca ctatccgact
    11041 gagttcgcag aaccccatcg ccagataaca ccgttccagt gtccaaaatt aagttaattg
    11101 cccgcttctt gataaccagt gatgcattgt gatctgcatt gtcagtattt ccacaattac
    11161 cgcaaacaaa cagggcttgt gttttgcgat tgtcgggatg agtgtgaccg cattttgcgc
    11221 actcctgact ggttgttggt gcgggtattt taaataccgc tttgctggat gaataagcct
    11281 tgtagtaggt gtaagtctcg atcacatgcc agcccacatt aagaatagac ttattcagtc
    11341 ctgctttctg cttggcttta tttgatatga atcgaccttg ttcatcctgt tttgctttcg
    11401 gccttctcgt catccttgcg gttcgtaacg cctcaaacac aatgattttg gcgctgctat
    11461 caaccaataa ccgactggtc ttatgcgcaa aatcatttcg tatgttagcc tttttagcat
    11521 gatgaaccgc aattcgatgc ttggtcttgg ctctgcggtt agagcctttt tgctgccttg
    11581 ccagtttgcg ctgcaatcgc ttgatatagc ggtctgcttt gctcatgttc tttttctggc
    11641 tatgggtgaa atcataggtt tgttcgccag cacaaacggg gatcgccacg cctcggtcaa
    11701 cacccatggt gtgctcttcc agatattctc tggtcgcccc ttgcagaaaa gctaagtgct
    11761 cttcattggt acttagtttg cgatcaggct gtccttgctc atagcagaat gacacataat
    11821 agtggccgcg ctcttttctc acataaagcg agtttgggat ctcaaatttg ccatgtgcct
    11881 taaaggacag ataaccgata ttgttggtct ttgtcccaat aaacaggcgc acgttgccgt
    11941 catcgcaatg gtcgaaacgg aacacttcac gggtaagata aatgcttcct ttgtccgttt
    12001 taggttttcg ctttggcctg ccgcatttcc cgctcatgaa tttctgataa gtttgatacc
    12061 agttaaccgc gctattacgc aagatttgac tagggcattc acttagccac ggagaaagct
    12121 ctttggattt gaattgtgaa gtggtctggt cgatgggcgc gtaagttccg atggtgcaat
    12181 atttacgggc ataggttcgg taataacgct cttcttctac cttggcattc cagatactac
    12241 gagcgcaccc catccactga ctcaagatca gtttttggtg agatgtcggg ttagcgcgta
    12301 gcttgatgcc agttaacatg atgtccgttt atttgctatt tacacctgaa attattacac
    12361 ttacttaaac tttgtcaatc tagcatgtgg ttataatgta cgattggaga acaggtagaa
    12421 gctgcatttt taaaaacaac gttcatctag tctttgttac aaagtatcgt cgtggtgttt
    12481 ttaccaaaga aatgcttgaa cggactgagg caataatgaa agagacttgt gagcagatgg
    12541 attgtgagct actggagttt ggtggagagg acgatcacat ccatatgatg gtgtccgtac
    12601 atccaaaatt ggcaatctca aatttagtca gcaagttaaa aggtaaatcg tcttacatga
    12661 tccggcgaga gtattgggac agggtaaaaa caatgctttg gggcaaccat ttctggtcgc
    12721 caagctactg tgtggtttct tgcggagggg ttgccctcga tgttgttcgg gagtacatca
    12781 acaaccagaa cgaaccgccc agcgaaaaag ccatgaagac atcacaagcg ttgaagcaaa
    12841 gaaaagagta gaaaccactt gcttgactcg cccctaaagg agcgagattg cgcaagcact
    12901 ccgttcaaga gctaaacagg agtaaataaa aatgagttta attattaaag cgagaaacat
    12961 acgcttggat tatgctgggc gtgatgtttt ggatattgat gaattggaaa ttcactctta
    13021 tgaccgtatt ggtcttgtgg gtgataacgg agcaggaaag agtagtttac tcaaagtact
    13081 taatggcgaa attgttttag ccgaagcgac attacagcgt tttggtgatt ttgcacatat
    13141 cagccaactg ggcggaatcg aaatagaaac ggtcgaagac cgggcaatgt tatctcgcct
    13201 tggtgtttcc aatgtacaaa acgacacaat gagtggcgga gaggaaactc gtgcaaaaat
    13261 tgctgccgca ttttcccaac aagtacatgg cattctagcg gatgaaccaa ccagccacct
    13321 tgatctcaat ggaatagatc tacttattgg tcaacttaaa gcatttgatg gagcattact
    13381 tgttatcagt catgaccgat attttcttga tatggttgta gacaagatat gggagttaaa
    13441 agacggtaaa attacggaat attggggtgg ttactcggat tacttgcgtc aaaaagaaga
    13501 agagcgacaa caccaagccg tagaatatga gctgatgatg aaggaacggg agcgattaga
    13561 atctgctgtg caagaaaaac gccagcaagc taatcgatta gacaataaga aaaaaggaga
    13621 aaaatccaaa aactctaccg aaagtgctgg acgacttggg catgcaaaaa tgactggcac
    13681 caagcaaaga aaactgtatc aggcagctaa gagtatggaa aagcgtttgg ctgcattaga
    13741 agatattcaa gcaccagagc atttgcgttc tattcgtttt cgtcaaagtt cagccctaga
    13801 actgcacaat aagttcccga ttacggcaga tggtctgagc ttaaaatttg gtagccgtac
    13861 tatctttgat gacgctaact ttataatacc gcttggcgct aaagtcgcta taactggatc
    13921 gaatggaaca gggaaaacgt ccttgttaaa aatgatatca gaacgtgctg atggattaac
    13981 catatctcca aaagctgaaa ttggctactt tacacaaaca ggatataaat ttaacacgca
    14041 taaatctgtg ctctccttta tgcaggaaga gtgcgagtac acagttgcgg aaattcgtgc
    14101 agtattggct tcaatgggga tcggagcgaa tgatattcaa aaaaacttat ccgacttatc
    14161 gggaggtgaa atcatcaaac tgcttttatc caaaatgctt ttaggaaaat ataatatttt
    14221 gcttatggat gaaccaggaa actatcttga cctaaaaagt attgccgcat tagaaacaat
    14281 gatgaagtcc tatgcaggaa ctattatctt cgtatctcat gacaagcaat tggtcgataa
    14341 tattgctgac attatctacg agatcaaaga ccacaaaatc atcaagactt ttgagagaga
    14401 ttgttaatga tagccaatct aatccgaaca ttaattattg aactctttaa aggaaattaa
    14461 aaatgacaat tcaagatatt caatcacttg ctgaagcaca cggcttgttg cttacggaca
    14521 aaatgaattt caatgaaatg ggcattgatt ttaaggtcgt ttttgctctt gatacaaagg
    14581 ggcaacaatg gttgctgcgt attcctcgtc gtgatggcat gagggaacaa atcaagaaag
    14641 aaaaacgcat tttagaattg gtaaaaaaac atctttctgt agaggttcct gattggagaa
    14701 tttcatctac agaattagtg gcttatccca tacttaaaga taatcctgtt ttaaatttgg
    14761 atgctgaaac ctatgaaata atttggaata tggacaaaga tagcccgaaa tacataacat
    14821 ctttggcaaa aaccttattt gaaatccata gtattcctga aaaagaagtt cgggaaaatg
    14881 atttgaaaat tatgaaacct tcagatttaa gacctgaaat agcaaacaat ttgcagttag
    14941 taaaatctga aattggtata agtgagcaat tggaaacccg ctacagaaaa tggttggata
    15001 atgatgttct atgggcagat ttcacccaat ttatacatgg cgatttatat gctgggcatg
    15061 tactagcttc aaaggatgga gctgtttcag gcgttattga ttggtcaaca gcccatatag
    15121 atgacccagc gattgatttt gctgggcatg taactttgtt tggagaagaa agcctcaaaa
    15181 ctctaatcat cgagtatgaa aaactagggg gtaaagtttg gaataaacta tatgaacaga
    15241 ctttagaaag agcagcggcc tctcctttga tgtatggttt atttgcctta gaaactcaaa
    15301 atgaaagcct tatcgttgga gcaaaagctc agttgggagt tatataattt aaaaatatga
    15361 ttgctgagaa ctgccttgtt ttgaaacttg gttggcttta attagttttt agtattcttt
    15421 ataggggttg taagccggaa acccagaaat ttccgtcagc cgatcaacat ggcttgtctc
    15481 gcgcttggtc gatgagttcc tgcatcgccc gcatgacttc ttcgtgggtg tacgacttgg
    15541 cgttggggtc gtcggcctct cggagagctt cctcgaccac gcgggtcatc cgcgcatatt
    15601 cttccggcca cagcgcttgc tccatgcgca gcgacgcctg cccaagcagg tgcagcaggc
    15661 cgaacagccg catgtcattg gtggcgacga cgtgctctcg aatccgctcc tggatcacct
    15721 cgcaggcccg atgcgcctct ggcgtcgccg tgccctcgta gccggctggg agttctgctt
    15781 cttcagcgat tcgcgcccaa gcgatagcca gcgcctcgat ggtggacagg ttcatttgct
    15841 catccacttg cgcagcagac gctttttcag ggaggcgcgc tcttgcggat tgcgtccctt
    15901 gtggttggca atgcgatccg ccgtggcggc ctggcgcttg atgggccagt aggagcggcc
    15961 atccttaccc atcgaccaga cgttgctgac ctggttttcc agtagaggca gatgggcgca
    16021 tagagcttcc ggcgacgcgc tggccagcgc ggtgcgctcg tgagttcgcc agcgctgatg
    16081 ccagagtttc ttgtcctcgc gctcgctacg gcaggtcgtg tgcccaacga tgggcgtttt
    16141 gcggcggctg cggctcatga tgtggttgtc tccaagaaca ttcaggacag gctttctggg
    16201 tagagcgccg tcaaccggga cagggtttct tgcacttgtt ccagcgaggt catcagatga
    16261 tcaacctgat cctgaagatc cacggcgaga tcaaatagct cagccactcg gctgcgtgat
    16321 ccctcgttga acgcggccat tgccagttga tgcagcttca acaggtcggt gcgcagttgc
    16381 ggaggtgcgc cgtctgcgct gtcattcaaa tcgccgcgca gcacgtccac ggcatcgact
    16441 gcacgcagca gtgccgtggt atcgaaattc tcgggagtca gttcgtccca ttcgtcgtcg
    16501 gtgatgcggg ctgccatcag gagggctccg attaagcggt tgcgagcgtt agatgcccga
    16561 tcggctcggc tgctggccgt accttgattt cgatgtcgta gccgaggcga ttcagacaat
    16621 ccatcagctt gcgttcggat agattggtga agtcgccgcg catcatgccc gacaccttcg
    16681 gttgcgggat gcccatgcgt ttggccgccg cttgttgagt cagcccaagg gcgcgcatgg
    16741 ccctcctgat ctcgaccacc aggccggtct tgatcttgag cttttcagcg tcaggcagtc
    16801 caaggtcggc aaagacgttg cccgagctgc gctgaacctc gacgccttca atgattcgtt
    16861 tttgcatttc gtagctcctg tgccaatacc tcggccacct tcagccgagc gcggatgatg
    16921 tccatgtcgg cctttggcgt ggcgattccg ctcttgctct tcttctggaa gcagtgcagg
    16981 acgaacaccg cttccgcaaa cttgaccgtg tataccgctc gataggtgcc gccggcatcg
    17041 tcttcgacga cctccagcac gccggcacca ccgaacccct tgagcacctt tgctgcgtca
    17101 tcctgatcgc ctatctgcgc caacgagagc gcgtaaccga aacggcgacg cacgtcggac
    17161 ggcaacgcca tcaaatcctt gtggctgctc gcgatccatt cgagcggttt ttctttgttt
    17221 gtcatgacgg aattttatac ctgttcaggt aatgatgtaa acgcggcaac ctcaaggagg
    17281 tgtcgtaaaa catttgtttt gcgacaggct gtcagccgcc gctgtgctac ctgtgcaaca
    17341 ccccctcaaa aatgtacgga aaactctatc gctattcact attatgcgga aacctgtttt
    17401 tgatggttat ccgcctatgt tggttggcta catgcgcgtg tcgtcggact ccgaccgcca
    17461 gagcacggac ttgcagcgcg acgcgctgct cgccgccggc gtcgatccgc gtcacctgtt
    17521 tgaggatcgt gcctctggcg cgaaggatga ccgtgccggc ttggcgcggg cgcttgagtt
    17581 cgttcgagcc ggcgatgtgc tggtggtgtg gaaactcgac cggctcggtc gctcgctgtc
    17641 gcacctgctc gccattgtga cttcgctcaa ggacaagcgg gtggcgttcc gctcgctgac
    17701 agagaacctg gacactacga cgccctcggg cgaattcctg ttccaggtgt tcggtgcgct
    17761 cgcgcagtac gagcgcgcct tgattcagga gcgcgtcgtc gcgggcttgg ccgccgcacg
    17821 caaacgcggc cggatcggcg gccggccgca ggcgatcact ggtgagaagc tggacgccat
    17881 cgtcgccgcg ctcgatggcg gcatgtctaa ggcggcggtg tgccgcaact tcaatgtcaa
    17941 gcgcactacg ttgatcgaaa cattgacgcg agcaggttgg cgtggtgcgg gaaggacggt
    18001 cgatgagcaa caagaataag ctactcaccg tcttttctga cgcagagcag gaagccttgt
    18061 acggcctacc ggacttcgac gatgctcagc ggctggaata cctggcgttg accgaatctg
    18121 aactggcgtt cgccagcagc cggcctagcc tgcaggccca agtctattgc gtcttgcaga
    18181 tcggctactt caaggccaag catgctttct tccgcttcga ttggcatgag gtcgaggacg
    18241 attgcgcctt cgtgctgagt cgctatttcc acggcgaagc gttcgaacgc aaggcgatca
    18301 ccaagcatga gcactacagc cagaggggtc agatcgccga actgttcggc taccggtcgt
    18361 gggcggctag cttcctgccg caactggcac agcaggctga acagatcgtg cggcgcgacg
    18421 taatgccagg attcgtggcc gccgaactga tcgtttggct cagcgagcac aaaatcatcc
    18481 ggcccggcca caccacctta caagagctgg tcagtgaagc cctgtccacc gaacgcaggc
    18541 gcttgggcgg cttgctggca gaagtgttgg acgaatcggc caaagctgcg ctgggccagc
    18601 tcctggtgcg tgacgacacc ctgtctcaac tggcagcgct caagcaggac gctaaagatt
    18661 tcggctggcg tcagatggca ggggagcgcg agaagcgcgc cacgctgaag tccttgcacg
    18721 ggatcgccaa ggcgctgctg cccaagctcg gcatctcgca gcagaacctg ctgtactacg
    18781 cgagcctggc gaacttctat accgtccatg acctgcgcca cctgaaggcg gagcagaccc
    18841 ggctctacct gctgtgctat gcctgggtac gttaccggca gctcaccgac aacctggtcg
    18901 acgcgatggc cttccacatg aaaaaacttg aggacgagag ccgcacgggt gcgaaacagt
    18961 cctttgtcgc cgaacagctg cgacgccatc aggaaacgcc gcaggttggc cgcctgctgt
    19021 cgctgtatgt ggacgacagc gtggccgatc cgacgccgtt cggcgaggtg cgccaacgcg
    19081 cctacaaaat catgtccagg gaattgctgc aaaacacggc gcagcgcatg agcgtcaagc
    19141 cactgaacaa actggcgctg cactggcagg cggtggacgg cctggccgaa cgcattcgac
    19201 gccatctacg gccgctgtac gtcgcgctcg acttcgccgg cacggccccc gataacccat
    19261 ggctcgcggc gctgacttgg gccaagagcg tgttcgccaa gcagcagcgc ctatcacaac
    19321 ggccactcga cgaatgtccg gcggcaacgc tgccgaaacg cttgcgtccg tacctgctga
    19381 tgttcgatgc cgaaggcacg ccgacaggcc tgcatgccga tcgttacgaa ttctggcttt
    19441 accgtcaggt caggaaacgc ttccaggcgg gcgagctcta cattgacgac agcttgcagc
    19501 accggcattt gtccgacgag ttggtttcga tggacgagaa agccgccgtg ctcgcgcaga
    19561 tggacatccc cttcctgcgg cagccggtca gtgcccagct cgatgcactg gcggccgagt
    19621 tgcgtgcgca atgggtggcg ttcaatcgcg agctgaaaca gggcaagctg acgcacctgg
    19681 aatacgacaa ggacacgcag agactgacct ggcgcaagcc caagggggag aaccagaagg
    19741 cgcgcgagca agctctctac gagcaactgc catactgcga tgtcgccgac gtgtttcgct
    19801 tcgtcaacgg ccagtgccag ttcctgtcgg cgctgacacc attgcagcca cgctatgcga
    19861 agaaggtagc cgacgccgac agtctgatgg cggtgatcat tgcccaagcc atgaaccacg
    19921 gcaaccaggt tatggcacgt accagcgaca tcccgtacca cgtcctggag agtacctacc
    19981 agcagtacct gcgccaggcg acgctacatg tggccaacga ttgcatcagc aacgccatcg
    20041 ccgcactgcc gatcttcccg cattactcgt tcgacctcga ttcgttgtac ggtgccgttg
    20101 atgggcagaa attcggcgtc gagcgaccaa ctgtgaaggc gcgctactcg cgcaaatatt
    20161 tcggccgcgg caagggcgtc gtcgcctaca cgctgctgtg caatcacgtg ccgttgaacg
    20221 gctacctgat aggcgcacac gagtacgagg ctcaccacgt gttcgacatc tggtaccgca
    20281 acacgtcgga catcgtgccg agcgcgatca ccggcgacat gcacagcatc aacaaggcca
    20341 acttcgccat cctgcactgg ttcggacttc gtttcgagcc gcgcttcacc gacctcgacg
    20401 accagttgca ggagctgtat tgcgccgatg atctggcatt gtacgagaaa tgcctgatcc
    20461 ggccggctgg ccagatcgac cggcaactca tcgtcggtga gaaggcgaac atcgaccgaa
    20521 tcgtcgccac actgggcctg aaggaaatga cgcagggcac gctgatccgc aagctgtgca
    20581 cctatacggc gccgaacccg acgcggcgcg caatcttcga gttcgacaag ctcatccgca
    20641 gtatctacac actgcgctac ctgcgcgacc cgcaactgga gcgtaatgtt caccgctcgc
    20701 agaaccgcat tgagtcctat caccagctac gctcgaccat cgcccaagtc ggtgggaaga
    20761 aggaattgac cggccgcacc gacatcgaaa tcgagatcag caaccagtgc gccaggctga
    20821 tcggcaacgc gatcatcttc tacaactcgg cgatcctgtc cctgctgctg acgaagtacg
    20881 aggcagctgg caatgccaag gcgctggcgt tgatcacgca gatgtcgcca gcggcctggc
    20941 ggcacatcct gctgaacggg cattacacct tccagactga cggcaagttc atcgacctgg
    21001 atgcgctcgt ggcgggactg gagctgggct gacggaaatt tctgggattc cggcgtacaa
    21061 ccccagctcg acgactaccg ataaaacgca accgccgcaa acagacaaga aaaagcccca
    21121 actgataaca gttggggctt cagtattgtg attggtggag caatagcacc ctgaacccaa
    21181 aaccttctcg ctcaaccggt agtggctgat aacaactcgt gagggctatt gcgggttaag
    21241 catttagcga tgtctagggc cagactggac gtctgaacgc aagccgctga tactgtacat
    21301 aaccacagta tcagcggagg atacccatgt cgctggcaag gaacgccacg gcgagtcaat
    21361 cgcccactca aacaaacggt tacgaacgcc accaacccga ccagacgctg ctctaccagc
    21421 tggttgagca gcactaccca gccttcaaag cctcactcga agcccaaggt caacacctgc
    21481 ctcgctacat ccaacaagaa ttcaacgacc tcctccaatg tggccgtctg gagtatggtt
    21541 tcatgcgggt tcgctgcgag gattgtcatc acgagcgtct ggtcgccttc agctgtaaac
    21601 gacgcggctt ttgccctagc tgcggtgccc gccggatggc cgagagtgcg gcgctgctga
    21661 tagacgaagt cttccccaag gagcccattc gccagtgggt gctcagcttt cctttccagc
    21721 tacgcttttt gctggctcgc catccccagc tgatgggcca ggtcttgagt atcgtctatc
    21781 gtacactctc aactcatctg atcaaaaaag ccggttacac caaagcctct gcacaaactg
    21841 gctcagtgac tcttatccaa cgctttggct ccgcgctaaa tctcaatgtc cactaccaca
    21901 tgctgtttct cgatggtgtc tatgccgaag atgactatgg caagcaacgc ttccatcgtg
    21961 tcaaggcacc cacttacgat gagctgaata cgctcgctca caccctcagc catcgcatcg
    22021 ctcgctgcat ggaaaagcgt gggattttgg agcgtgatgc cgagaatacg tggttgacac
    22081 tggaagaggg cgaagacgat acgctgactc aattacatgg tgcttcggtt acgtatcgca
    22141 ttgccgtcgg cccccagcaa gggcgcaaag tcttcaccct gcaaaccttg ccagggcgtg
    22201 aggataaagc cgactcaagc agtcgagtag ccaaccatgc tggtttctcg ctacacgccg
    22261 gtgtgatggc cgaagcgcat cagcgggata agcttgagcg cttgtgtcgc tacattagtc
    22321 ggccagcggt ttcagaaaaa cgtctggcat taaccgccaa tgggcaggtg cgttacgagc
    22381 tcaaaactcc gtaccgcaat ggcaccaccc atgtgatctt cgagccgctg gacttcatcg
    22441 ccaaactcgc tgcgttggta cctaagccgc gagtcaacct cacacgcttc cacggcgtct
    22501 ttgcaccgaa cagcaaacac cgagttcaag taacacccgc caagcggggc aagaagcccg
    22561 acaaatcgga aggtctcgat actaactggc gtgacaagag tcctgcagag cgccaccgcg
    22621 ccatgacctg gatgcaacgc ctcaagcgag tcttcaatat tgatattgaa gtctgcgaac
    22681 actgcggcgg tcacgtcaaa gtgattgcca gcatcgaaga tccgaaggtc attgagcaga
    22741 ttctcaagca tctgaaacag aaaacagcca aggcgaatgc cgccaagcag cgtgagctgc
    22801 caccagaacg agcgccgcca ctgactccca gcctgttcga tccatcacag agtcgtctct
    22861 ttgactgacg accccaaatc caacactgct caacactgcc aacttttaaa cggggcggtg
    22921 gggcagtttg tatctctcga gctatcaggc tagagatttt accgccaaat cgaaccttat
    22981 tagagcggtt taggctggac cggcagttaa aattggggct tgagcggtaa acgagtgagg
    23041 gaatttcagg taagatactt cggatgagga gcaaaaaggt ggtttatact tcctataccc
    23101 ttcaaatcaa atgttttttg gagctacagc atggaaaaat caaagcaatt atataatcaa
    23161 gtgaacttct cacatcagga cttgcaagaa catatcttta gcaattgtac ttttatacat
    23221 tgtaatttta agcgctcaaa ccttcgagat acacagttca ttaactgtac tttcatagag
    23281 cagggggcac tggaagggtg cgatttttct tatgctgatc ttcgagatgc ttcatttaaa
    23341 gattgtcagc tttcaatgtc ccattttaag ggggcaaatt gctttggtat tgaactgaga
    23401 gattgtgatc ttaaaggggc aaattttagc caagttagtt ttgtaaatca ggtttcgaat
    23461 aaaatgtact tttgctctgc atacataaca ggttgtaact tatcctatgc caattttgag
    23521 cagcagctta ttgaaaaatg tgacctgttc gaaaatagat ggattggtgc aaatcttcga
    23581 ggcgcttcat ttaaagaatc agatttaagt cgtggcgttt tttcagaaga ctgctgggaa
    23641 cagtttagag tacaaggctg tgatttaagt cattcagagc tttatggttt agatcctcga
    23701 aagattgatc ttacaggtgt aaaaatatgc tcgtggcaac aggagcagtt actggagcaa
    23761 ttaggggtaa tcattgttcc tgactaagcg caagattcgg ctacgcacat aacaaagcgc
    23821 ttaagacaga ttcgcaacgc tgggcatttt cggtttgctt tgaatttagt gtttacggca
    23881 caatggttta ggttgggtgg catgttgctc actacttaac gcggcgttat gttttcggga
    23941 taacttgagg aacagaaatg gatttcattt ggttggtttt agttttgggt tctgctgctg
    24001 cattctacta tttcgtatca tattcgaagc cacaggatga tgattggcac aaattaccga
    24061 cacttgagga ttatttgata aagcatccag aatgtaaaac ggcagattca gaaagtgcga
    24121 aatgctttag ttgtggttca gataaagtga tttttcaacc attaacagct catgcagatc
    24181 atcgttataa acatatttgc ttatcttgca aaaaaacact ttttagaagt aaggcaataa
    24241 tgtcttaaac cagttgatga tcctaagaac attttcaata aaatcagctg gttgcaataa
    24301 aacataacaa acggttcaag agggacaacc aacgcgtggc atttttatta tgcgttggtt
    24361 gccccttaac cgggcgttat aagcaaattc agctccagag gatgaaaaat ggaaatcgag
    24421 tacaaagtaa accatccaat ctcagttgaa caattcgtga gtttactgaa gaaaacttca
    24481 ttgggtgagc gtcgtccttt ggataatgag tcaactattc agggtatgct cgacaactct
    24541 aatttgatgg tgaccgcatg gctgaacgat cagcttgtcg gtgtggctcg ctcagtgaca
    24601 gattttcatt attgttgcta tctaagttga ctgtgcgtga aaaagaaagt tttgtgtgat
    24661 ggcgttgaag atcgcaccgt taagctctta tgtgggatgg tgcagagctc gacgactacc
    24721 gataaaacgc aaccgccgca aacagacaag aaaaagcccc aactgataac agttggggct
    24781 tcagtattgt gattggtgga gcaatagcac cctgaaccca aaaccttctc gctcaaccgg
    24841 tagtggctga taacaactcg tgagggctat tgcgggttaa gcatttagcg atgtctaggg
    24901 ccagactgga cgtctgaacg caagccgctg atactgtaca taaccacagt atcagcggag
    24961 gatacccatg tcgctggcaa ggaacgccac ggcgagtcaa tcgcccactc aaacaaacgg
    25021 ttacgaacgc caccaacccg accagacgct gctctaccag ctggttgagc agcactaccc
    25081 agccttcaaa gcctcactcg aagcccaagg tcaacacctg cctcgctaca tccaacaaga
    25141 attcaacgac ctcctccaat gtggccgtct ggagtatggt ttcatgcggg ttcgctgcga
    25201 ggattgtcat cacgagcgtc tggtcgcctt cagctgtaaa cgacgcggct tttgccctag
    25261 ctgcggtgcc cgccggatgg ccgagagtgc ggcgctgctg atagacgaag tcttccccaa
    25321 ggagcccatt cgccagtggg tgctcagctt tcctttccag ctacgctttt tgctggctcg
    25381 ccatccccag ctgatgggcc aggtcttgag tatcgtctat cgtacactct caactcatct
    25441 gatcaaaaaa gccggttaca ccaaagcctc tgcacaaact ggctcagtga ctcttatcca
    25501 acgctttggc tccgcgctaa atctcaatgt ccactaccac atgctgtttc tcgatggtgt
    25561 ctatgccgaa gatgactatg gcaagcaacg cttccatcgt gtcaaggcac ccacttacga
    25621 tgagctgaat acgctcgctc acaccctcag ccatcgcatc gctcgctgca tggaaaagcg
    25681 tgggattttg gagcgtgatg ccgagaatac gtggttgaca ctggaagagg gcgaagacga
    25741 tacgctgact caattacatg gtgcttcggt tacgtatcgc attgccgtcg gcccccagca
    25801 agggcgcaaa gtcttcaccc tgcaaacctt gccagggcgt gaggataaag ccgactcaag
    25861 cagtcgagta gccaaccatg ctggtttctc gctacacgcc ggtgtgatgg ccgaagcgca
    25921 tcagcgggat aagcttgagc gcttgtgtcg ctacattagt cggccagcgg tttcagaaaa
    25981 acgtctggca ttaaccgcca atgggcaggt gcgttacgag ctcaaaactc cgtaccgcaa
    26041 tggcaccacc catgtgatct tcgagccgct ggacttcatc gccaaactcg ctgcgttggt
    26101 acctaagccg cgagtcaacc tcacacgctt ccacggcgtc tttgcaccga acagcaaaca
    26161 ccgagttcaa gtaacacccg ccaagcgggg caagaagccc gacaaatcgg aaggtctcga
    26221 tactaactgg cgtgacaaga gtcctgcaga gcgccaccgc gccatgacct ggatgcaacg
    26281 cctcaagcga gtcttcaata ttgatattga agtctgcgaa cactgcggcg gtcacgtcaa
    26341 agtgattgcc agcatcgaag atccgaaggt cattgagcag attctcaagc atctgaaaca
    26401 gaaaacagcc aaggcgaatg ccgccaagca gcgtgagctg ccaccagaac gagcgccgcc
    26461 actgactccc agcctgttcg atccatcaca gagtcgtctc tttgactgac gaccccaaat
    26521 ccaacactgc tcaacactgc caacttttaa acggggcggt ggggcagttt gtatctctcg
    26581 agctatcagg ctagagattt taccgccaaa tcgaacctta ttagagcggt ttaggctgga
    26641 ccggcagtta aaattggggc ttgagcggta aacgagtgag ggaatttcag gtaagatact
    26701 tcggatgagg agcaaaaagg tggtttatac ttcctatacc cttgagcggt aaacgagtga
    26761 gggaatttca ggtaagatac ttcggatgag gagcaaaaag gtggtttata cttcctatac
    26821 ccgaccattg cccagcaaac gccgctgctg ctgctggacg agcccacctc tgcgttagac
    26881 ctgggccacc agatcgaagt cttcgagctg gtgcgcacgc tggcctgcca tggccgcacc
    26941 gtggtgatgg tgctgcacga cctggccagc gcctgccgct acgccgacca cctgattgcc
    27001 atgcgcgatg gccagatcgt tgaccagggg gcaccagccg atgtggtgac accagccttg
    27061 gtgcgcgcgc tctatcaggt agaatgcacg ctgttgctgg acccggatac cggcagcccg
    27121 ctgctcgcca acgtgcgccg cgccgaacgt tctgaatgag cggagccccg tgcaggggtt
    27181 ccaggccaaa aaatacatga caacacgcta aaaggaactc tcgtggcctc ttcaacgccc
    27241 agttcttccg ccagttctgc caaccaaagt tttcaggcgt tggtcaggct gctgcgctac
    27301 gccaaggggt atcgtcggcg gattaccgct gccacgatct gctccatcat caacaagctg
    27361 ttcgatattg ccccggaaat tctcatcggt gtcgccattg atgtggtggt caaccaggag
    27421 aacagcttcg tggcccgtct ggggttcgaa accccgcacg agcagatcgc catcctcgcg
    27481 gtgctgacct tctttatctg ggcgggggag tcgctattcg agtacctgta ccaggtgctg
    27541 tggcgcaacc tggcccagcg gctccaggcc gacctgcgcc aggatgccta tgagcacgcc
    27601 cagcggctcg acatggcgtt tttcgaatcg aagagctcag gccagctggt ggccaccatg
    27661 aacgatgacg tcaaccagct ggagcgcttt ctggacggcg gcgccaacgc gctgattcag
    27721 gtgggagtga ccgtggtggc ggtgggcgcc gtgttcttcg tgctttcccc gctgattgcg
    27781 ctgctggcct tcacgcctat cccgctgatc atctggggag cgttcttctt ccagcgcaag
    27841 gcggggccgc tctacagcga ggtgcgtgag aaagtgggcg acctttccag ccggctctcc
    27901 aacaacctga gcggcattgc caccatcaag agcttcacca gtgaagcccg tgaggccgaa
    27961 cgcctgcgca gcgccagtga agcctatgta gatgccaacc gtcaggcgat cagggtcagt
    28021 tcggcgttta ttccggtcat ccgcatggcc attctggcgg gctttttggc caccttcacc
    28081 gtgggtggca tgatggcgct caacggcagc ctcaatgtag gcgcctacgg cgtgctggtg
    28141 ttcctgaccc agcgcctgct ctggccgctg accgggctgg cccaggtcat cgacctgttc
    28201 gaacgcgcca tggccagcac caagcgtatc ctggatttgc tggaagtccc cattactgtg
    28261 aaagacgaca gcacccaggc cttggccgca ccggtgaaag gcgaggtgcg tttcgaagcg
    28321 gtgagcttcc agtatgaagc cagccaggta ggcgtgaacg cggtagacct gcacgttccg
    28381 gcgggcacca cgctggccct ggtgggggcc acggggtcgg gtaaatcgac gttgatcaag
    28441 ctgctgctgc gcttctacga ccctgccagc ggccgcgtgc tggtcgatgg ccagcccatt
    28501 accgaggtca gcatgcattc gctgcggcag gctatcggcc tggtcagcca ggacgtgtac
    28561 ctgttcgagg gcagtattcg cgacaacatc gcctacggca tgcccgatgc cgacgaagcc
    28621 gccatcatcg aggccgccaa aaccgcagaa gcctggagct ttatcgagac gctgccccaa
    28681 gggctggaca ccccggtggg ggagcggggc gtgcgccttt ccggtggcca acgccagcgc
    28741 ctttccctgg cccgagcgct gctcaaggac ccgcccattc tggtgctgga cgaagccacc
    28801 agcgccgtgg acaacgaaac cgaagcggca atccagcgct cgctgaagcg cattgcccac
    28861 gggcgtacgg tgatcatgat tgcccaccgg ctttccacca tcgtgcatgc cgatgaaatc
    28921 gtcgtgatcg agaagggcca ggtagcggag cgcggcagcc atgccagcct gctacaggcc
    28981 gatggccact acgccgccca gtggcgggta caaaccggag ccgcccaggc gggcgatgtg
    29041 gaagtgctgg gccgttaggc cgtcacttgc cacgtactca agcgccgccc catgggcggc
    29101 gcttgcgttt agcggttcac caacagcgcg ttcagggtca ccggcacatg ctcatcgatc
    29161 tgctgatagc ccagcaggga aagcaccgtg cgcagcgtgc tgttggccat cagggcattg
    29221 ccatccagcg ccattggttc ggcatgggtg acacgcactt cgttcagccc gacgcgggta
    29281 aagcgcagcg gcaccgcttc ctcctgggtc agccggtcgg tttggactcg aaaggtcagg
    29341 gtttccacca gctcctcgcc catgtccagg cggtccaggc gctcgggtgg catctgcgcc
    29401 accagcgtca ccagcggcgt attggccagc aggcccaccc acggcggcag gtcacccaaa
    29461 cgttgcaaca cgtcggtctg gctcagccgg agcggcaggc gcagcgtgcc atcgggggag
    29521 atatcgccct gcaaattgct cacgtgatga tgatgagttt gcggcgcgct accgtccaac
    29581 tgggtaatgg acgcccgcac ctgcgattgg gcagggtcca actgccagtc ggcctgaacg
    29641 ggcagcgcca gcagcagcgg aaaaagagca atcaaggctt tcacagcatg tctccataga
    29701 agcagtcatc agcagacccc ggccgcgcag cgtgaggata aacgtaggga ggaagaagaa
    29761 agtaaattcg gtattcccct tgataacgct aagaacttaa ctgtaggaga ttaatatgca
    29821 caaaccaacc ccattaaaac ggttgtcgat gatacttgct cgtgacctta atggtgccat
    29881 tggttacgaa ggttctttgg ccattaaatc ggacaatgat tttgcgtggt ataagaaaat
    29941 taccaaacca tttaagcacg ctgtttgtgg gcgagtaacc tatgaggaag atttgcccga
    30001 tatcgtcaaa aaacgccaca gattcatcat tattacccgt aatccagaca agtacgctag
    30061 tactcctgaa gcacagtata tgacgctctc agacgcgtta aaagagttac aagtttggga
    30121 cgtacctggt cacgacatta tctgcttagg tggtgctgaa atttacaagg cattattgcc
    30181 ttacgttagt actgtttacc tgactacatt cttttcagta gcagatgaag cagatactta
    30241 tttcaatgac tttacagata aatgggaatc agtaggggcc acttggttta acgactgcta
    30301 ctgcacccgt ctggagcgtg tatgtcaatc tacaaacaat attatctaac atgtaatgat
    30361 tgtggtgcaa tctaccaaga aatagcagag gagctttaga taccacctgc ttgtagattt
    30421 tcaactgtta atactgaccg tgcataataa gccctacaca aattgggaga tatatcatga
    30481 aaggctggct ttttcttgtt atcgcaatag ttggcgaagt aatcgcaaca tccgcattaa
    30541 aatctagcga gggctttact aagcttgccc cttccgccgt tgtcataatc ggttatggca
    30601 tcgcatttta ttttctttct ctggttctga aatccatccc tgtcggtgtt gcttatgcag
    30661 tctggtcggg actcggcgtc gtcataatta cagccattgc ctggttgctt catgggcaaa
    30721 agcttgatgc gtggggcttt gtaggtatgg ggctcataat tgctgccttt ttgctcgccc
    30781 gatccccatc gtggaagtcg ctgcggaggc cgacgccatg gtgacggtgt tcggcattct
    30841 gaatctcacc gaggactcct tcttcgatga gagccggcgg ctagaccccg ccggcgctgt
    30901 caccgcggcg atcgaaatgc tgcgagtcgg atcagacgtc gtggatgtcg gaccggccgc
    30961 cagccatccg gacgcgaggc ctgtatcgcc ggccgatgag atcagacgta ttgcgccgct
    31021 cttagacgcc ctgtccgatc agatgcaccg tgtttcaatc gacagcttcc aaccggaaac
    31081 ccagcgctat gcgctcaagc gcggcgtggg ctacctgaac gatatccaag gatttcctga
    31141 ccctgcgctc tatcccgata ttgctgaggc ggactgcagg ctggtggtta tgcactcagc
    31201 gcagcgggat ggcatcgcca cccgcaccgg tcaccttcga cccgaagacg cgctcgacga
    31261 gattgtgcgg ttcttcgagg cgcgggtttc cgccttgcga cggagcgggg tcgctgccga
    31321 ccggctcatc ctcgatccgg ggatgggatt tttcttgagc cccgcaccgg aaacatcgct
    31381 gcacgtgctg tcgaaccttc aaaagctgaa gtcggcgttg gggcttccgc tattggtctc
    31441 ggtgtcgcgg aaatccttct tgggcgccac cgttggcctt cctgtaaagg atctgggtcc
    31501 agcgagcctt gcggcggaac ttcacgcgat cggcaatggc gctgactacg tccgcaccca
    31561 cgcgcctgga gatctgcgaa gcgcaatcac cttctcggaa accctcgcga aatttcgcag
    31621 tcgcgacgcc agagaccgag ggttagatca tgcctagcat tcaccttccg gccgcccgct
    31681 agcggaccct ggtcaggttc cgcgaaggtg ggcgcagaca tgctgggctc gtcaggatca
    31741 aactgcacta tgaggcggcg gttcataccg cgccagggga gcgaatggac agcgaggagc
    31801 ctccgaacgt tcgggtcgcc tgctcgggtg atatcgacga ggttgtgcgg ctgatgcacg
    31861 acgctgcggc gtggatgtcc gccaagggaa cgcccgcctg ggacgtcgcg cggatcgacc
    31921 ggacattcgc ggagaccttc gtcctgagat ccgagctcct agtcgcgagt tgcagcgacg
    31981 gcatcgtcgg ctgttgcacc ttgtcggccg aggatcccga gttctggccc gacgccctca
    32041 agggggaggc cgcatatctg cacaagctcg cggtgcgacg gacacatgcg ggccggggtg
    32101 tcagctccgc gctgatcgag gcttgccgcc atgccgcgcg aacgcagggg tgcgccaagc
    32161 tgcggctcga ctgccacccg aacctgcgtg gcctatacga gcggctcgga ttcacccacg
    32221 tcgacacttt caatcccggc tgggatccaa ccttcatcgc agaacgccta gaactcgaaa
    32281 tctaacgtcc gttcgggcat cgaggtccat gtcggggtgg gacgggcccg tggcttcaag
    32341 atcacttgca gtccgaccgc gatgtcttgg ttgcgcgaga ggttgtcgat atcctccact
    32401 tccatcatca accctggata atgccgccgc cgtcatcgcc gccgacgccc gtgccgggct
    32461 tttcgggcct gtcaggcttg ctcggccttc agcctgcctg ggcgagatct ccggcggacg
    32521 gattaacggc ggagcttcgc cgcctttcgt gcgtgtgaag gccgaagata gttctctcaa
    32581 aaacatccgt ttatgagaga taccaaatgt cattttcaga agacgactgc accagttgat
    32641 tgggcgtaat ggctgttgtg cagccagctc ctgacagttc aatatcagaa gtgatctgca
    32701 ccaatctcga ctatgctcaa tactcgtgtg ggctctgttg caaaaatcgt gaagcttgag
    32761 catgcttggc ggagattgga cggacggaac gatgacggat ttcaagtggc gccatttcca
    32821 gggtgatgtg atcctgtggg cggtgcgctg gtattgtcgc tatccgatca gctatcgcga
    32881 ccttgaggaa atgctggcgg aacgcggcat ttcggtcgac catacgacga tctatcgctg
    32941 ggtccagtgc tacgccccgg agatggagaa gcggctgcgc tggttctggc ggcgtggctt
    33001 tgatccgagc tggcgcctgg atgaaaccta cgtcaaggtg cggggcaagt ggacctacct
    33061 gtaccgggca gtcgacaagc ggggcgacac gatcgatttc tacctgtcgc cgacccgcag
    33121 cgccaaggca gcgaagcggt tcctgggcaa ggccctgcga ggcctgaagc actgggaaaa
    33181 gcctgccacg ctcaataccg acaaagcgcc gagctatggt gcagcgatca ccgaattgaa
    33241 gcgcgaagga aagctggacc gggagacggc ccaccggcag gtgaagtatc tcaataacgt
    33301 gatcgaggcc gatcacggaa agctcaagat actgatcaag ccggtgcgcg gtttcaaatc
    33361 gatccccacg gcctatgcca cgatcaaggg attcgaagtc atgcgagccc tgcgcaaagg
    33421 acaggctcgc ccctggtgcc tgcagcccgg catcaggggc gaggtgcgcc ttgtggagag
    33481 agcttttggc attgggccct cggcgctgac ggaggccatg ggcatgctca accaccattt
    33541 cgcagcagcc gcctgatcgg cgcagagcga cagcctacct ctgactgccg ccaatctttg
    33601 caacagagcc tccgtcgcca tgctcacctc gctttggtgc acacgagtat tgagcatagt
    33661 cgagattggt gcagatcact tctgatattg aactgtcagg agctggctgc acaacagcca
    33721 ttacgcccaa tcaactggtg cagtcgtctt ctgaaaatga ca
//
