LOCUS       In127                  15062 bp    DNA     linear       29-SEP-2020
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Unclassified.
REFERENCE   1  (bases 1 to 15062)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of In127
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 15062)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..15062
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
     repeat_region   1..25
                     /gene="IRi_In127"
     CDS             complement(203..1216)
                     /gene="intI1"
                     /codon_start=1
                     /product="Integrase"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     misc_recomb     1297..1352
                     /gene="attI1"
     CDS             1362..2153
                     /gene="aadA2"
                     /codon_start=1
                     /product="Aminoglycoside-3''-adenylyltransferase AadA2"
                     /translation="MRVAVTIEISNQLSEVLSVIERHLESTLLAVHLYGSAVDGGLKP
                     YSDIDLLVTVAVKLDETTRRALLNDLMEASAFPGESETLRAIEVTLVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPAMIDIDLAILLTKAREHSVALVGPAAEEFFDPVPEQ
                     DLFEALRETLKLWNSQPDWAGDERNVVLTLSRIWYSAITGKIAPKDVAADWAIKRLPA
                     QYQPVLLEAKQAYLGQKEDHLASRADHLEEFIRFVKGEIIKSVGK"
     misc_recomb     2155..2214
                     /gene="attC_aadA2"
     CDS             2317..2664
                     /gene="qacED1"
                     /codon_start=1
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     misc_feature    2658..3629
                     /gene="truncated sul1"
                     /product="Truncated dihydropteroate synthase"
     CDS             3846..5060
                     /gene="floR"
                     /codon_start=1
                     /product="Chloramphenicol/florfenicol resistance, MFS
                     efflux pump"
                     /translation="MTTTRPAWAYTLPAALLLMAPFDILASLAMDIYLPVVPAMPGIL
                     NTTPAMIQLTLSLYMVMLGVGQVIFGPLSDRIGRRPILLAGATAFVIASLGAAWSSTA
                     PAFVAFRLLQAVGASAMLVATFATVRDVYANRPEGVVIYGLFSSMLAFVPALGPIAGA
                     LIGEFLGWQAIFITLAILAMLALLNAGFRWHETRPLDQVKTRRSVLPIFASPAFWVYT
                     VGFSAGMGTFFVFFSTAPRVLIGQAEYSEIGFSFAFATVALVMIVTTRFAKSFVARWG
                     IAGCVARGMALLVCGAVLLGIGELYGSPSFLTFILPMWVVAVGIVFTVSVTANGALAE
                     FDDIAGSAVAFYFCIQSLIVSIVGTLAVTLLNGDTAWPVICYATAMAVLVSLGLALLR
                     SRDAATEKSPVV"
     CDS             complement(5267..5893)
                     /gene="tetR(G)"
                     /codon_start=1
                     /product="Tetracycline repressor protein TetR, class G"
                     /translation="MTKLDKGTVIAAALELLNEVGMDSLTTRKLAERLKVQQPALYWH
                     FQNKRALLDALAEAMLAERHTRSLPEENEDWRVFLKENALSFRTALLSYRDGARIHAG
                     TRPTEPNFGTAETQIRFLCAEGFCPKRAVWALRAVSHYVVGSVLEQQASDADERVPDR
                     PDVSEQAPSSFLHDLFHELETDGMDAAFNFGLDSLIAGFERLRSSTTD"
     CDS             6045..7172
                     /gene="tetA(G)"
                     /codon_start=1
                     /product="Tetracycline efflux protein TetA, class G"
                     /translation="MGLGLIMPVLPTLLRELVPAEQVAGHYGALLSLYALMQVVFAPM
                     LGQLSDSYGRRPVLLASLAGAAVDYTIMASAPVLWVLYIGRLVSGVTGATGAVAASTI
                     ADSTGEGSRARWFGYMGACYGAGMIAGPALGGMLGGISAHAPFIAAALLNGFAFLLAC
                     IFLKETHHSHGGTGKPVRIKPFVLLRLDDALRGLGALFAVFFIIQLIGQVPAALWVIY
                     GEDRFQWNTATVGLSLAAFGATHAIFQAFVTGPLSSRLGERRTLLFGMAADATGFVLL
                     AFATQGWMVFPILLLLAAGGVGMPALQAMLSNNVSSNKQGALQGTLTSLTNLSSIAGP
                     LGFTALYSATAGAWNGWVWIVGAILYLICLPILRRPFATSL"
     CDS             7193..7984
                     /gene="lysR"
                     /codon_start=1
                     /product="LysR family transcriptional regulator"
                     /translation="MRRLRRNDGLNLLSNHLLSGRVPMMTLVHTLAVAEYLNFRHAAN
                     ALGVAQSSVSARVKALEEDLGILLFERHARGVRLTEAGRHFVERIAVGIDQLDHAVKT
                     AGMAAAGESGRLRIGIHALIPHSFLAKLIGQYRKDYPDVEVEIAEGPAREAVVQLRAG
                     RLDVAFVAGTPQPPDCHSRRTWTEPLLAVLPERHPLAKRSAVTWPDLAGETFLAYRKF
                     KRPFRAVCWVGGGRASPVLGTDRTSVSGISASRGHAAALSAAMLR"
     misc_recomb     complement(7832..7852)
                     /gene="oriIS"
     CDS             complement(8076..9608)
                     /gene="tnpA"
                     /codon_start=1
                     /product="ISCR3 transposase"
                     /translation="-
                     PRLATSRRQAAGCAPLPSAHTGSRYARHAPERTLLYALVEAHYPDFIARIEAEGRSLP
                     GYVREAFDAYLRCGVLEHGFLRVVCEHCRAERLVAFSCKKRGFCPSCGARRMAESARH
                     LVEEVFGPRPVRQWVLSFPYPLRFLFASKPEAIGPVLGIVQRVIAGWLADQAGIDRAS
                     AQCGAVTLIQRFGSALNLNIHFHMLWLDGVYVEATELPRRELRLHRARAPTTAQLTQL
                     AATIAHRVCRHLTRKGWLEGEGESAFLADSAAGDDSMDGLRMSSITYRIATGRDAGCK
                     VVTLQTLPGDAGSLEGEAGKVGGFSLHAGVAAEAHESHKLEKLCRYITRPAISEKRLS
                     IALQGRVRYQLKTPWRNGTTHVEWDPVDFIAKLAALVPPPRAHLTRFHGVFAPNANLR
                     AQLTPSGRGKRPAGDAAPVDVSAHDAPRSPEEKRRAMSWAQRLKRVFSIDVTACVHCG
                     GTVRIVASIEEPTAIRAILAHFEKHGAREEAHYRPAARAPPVQAA"
     misc_feature    complement(10188..10488)
                     /gene="truncated intI1"
                     /product="Truncated intI1 integrase (pseudogene)"
     misc_recomb     10573..10627
                     /gene="attI1"
     CDS             10694..11560
                     /gene="blaCARB-2"
                     /codon_start=1
                     /product="PSE family carbenicillin-hydrolyzing class A
                     beta-lactamase CARB-2"
                     /translation="MKFLLAFSLLIPSVVFASSSKFQQVEQDVKAIEVSLSARIGVSV
                     LDTQNGEYWDYNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPNSTVEIKKADLVTYSP
                     VIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGPKGVTDFLRQIGDKETRLDRI
                     EPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQKKLESWMVNNQVTGNLLRS
                     VLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQTQASMAERNDAIVKIG
                     HSIFDVYTSQSR"
     misc_recomb     11612..11674
                     /gene="attC_blaCARB-2"
     CDS             11777..12124
                     /gene="qacED1"
                     /codon_start=1
                     /product="Quaternary ammonium compound resistance protein"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     CDS             12118..12957
                     /gene="sul1"
                     /codon_start=1
                     /product="Dihydropteroate synthase"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     CDS             13085..13585
                     /gene="orf5"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHA
                     GRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAE
                     RLELEI"
     CDS             13609..13896
                     /gene="orf6"
                     /codon_start=1
                     /product="Hypothetical protein"
                     /translation="MSGWDGPVASRSLAVRPRCLGCARGCRYPPLPSSTLDNAAAVIA
                     ADARAGLFGPVRLARPSACLGEISGGRINGGASPPFVRVKAEDSSLKNIRL"
     repeat_region   complement(13908..13932)
                     /gene="IRt_In127"
     repeat_region   14031..14044
                     /gene="IRL_IS6100"
     CDS             14062..14856
                     /gene="tnpA"
                     /codon_start=1
                     /product="IS6100 transposase TnpA"
                     /translation="MLGGDWTDGTMTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEM
                     LAERGISVDHTTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYR
                     AVDKRGDTIDFYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELK
                     REGKLDRETAHRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALR
                     KGQARPWCLQPGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     repeat_region   14897..14910
                     /gene="IRR_IS6100"
     repeat_region   15038..15062
                     /gene="IRt_In127"
ORIGIN      
        1 tgtcgttttc agaagacggc tgcactgaac gtcagaagcc gactgcacta tagcagcgga
       61 ggggttggat ccatcaggca acgacgggct gctgccggcc atcagcggac gcagggagga
      121 ctttccgcaa ccggccgttc gatgcggcac cgatggcctt cgcgcagggg tagtgaatcc
      181 gccaggattg acttgcgctg ccctacctct cactagtgag gggcggcagc gcatcaagcg
      241 gtgagcgcac tccggcaccg ccaactttca gcacatgcgt gtaaatcatc gtcgtagaga
      301 cgtcggaatg gccgagcaga tcctgcacgg ttcgaatgtc gtaaccgctg cggagcaagg
      361 ccgtcgcgaa cgagtggcgg agggtgtgcg gtgtggcggg cttcgtgatg cctgcttgtt
      421 ctacggcacg tttgaaggcg cgctgaaagg tctggtcata catgtgatgg cgacgcacga
      481 caccgctccg tggatcggtc gaatgcgtgt gctgcgcaaa aacccagaac cacggccagg
      541 aatgcccggc gcgcggatac ttccgctcaa gggcgtcggg aagcgcaacg ccgctgcggc
      601 cctcggcctg gtccttcagc caccatgccc gtgcacgcga cagctgctcg cgcaggctgg
      661 gtgccaagct ctcgggtaac atcaaggccc gatccttgga gcccttgccc tcccgcacga
      721 tgatcgtgcc gtgatcgaaa tccagatcct tgacccgcag ttgcaaaccc tcactgatcc
      781 gcatgcccgt tccatacaga agctgggcga acaaacgatg ctcgccttcc agaaaaccga
      841 ggatgcgaac cacttcatcc ggggtcagca ccaccggcaa gcgccgcgac ggccgaggtc
      901 ttccgatctc ctgaagccag ggcagatccg tgcacagcac cttgccgtag aagaacagca
      961 aggccgccaa tgcctgacga tgcgtggaga ccgaaacctt gcgctcgttc gccagccagg
     1021 acagaaatgc ctcgacttcg ctgctgccca aggttgccgg gtgacgcaca ccgtggaaac
     1081 ggatgaaggc acgaacccag tggacataag cctgttcggt tggtaagctg taatgcaagt
     1141 agcgtatgcg ctcacgcaac tggtccagaa ccttgaccga acgcagcggt ggtaacggcg
     1201 cagtggcggt tttcatggct tgttatgact gtttttttgt acagtctatg cctcgggcat
     1261 ccaagcagca agcgcgttac gccgtgggtc gatgtttgat gttatggagc agcaacgatg
     1321 ttacgcagca gggcagtcgc cctaaaacaa agttagacat catgagggta gcggtgacca
     1381 tcgaaatttc gaaccaacta tcagaggtgc taagcgtcat tgagcgccat ctggaatcaa
     1441 cgttgctggc cgtgcatttg tacggctccg cagtggatgg cggcctgaag ccatacagcg
     1501 atattgattt gttggttact gtggccgtaa agcttgatga aacgacgcgg cgagcattgc
     1561 tcaatgacct tatggaggct tcggctttcc ctggcgagag cgagacgctc cgcgctatag
     1621 aagtcaccct tgtcgtgcat gacgacatca tcccgtggcg ttatccggct aagcgcgagc
     1681 tgcaatttgg agaatggcag cgcaatgaca ttcttgcggg tatcttcgag ccagccatga
     1741 tcgacattga tctagctatc ctgcttacaa aagcaagaga acatagcgtt gccttggtag
     1801 gtccggcagc ggaggaattc tttgacccgg ttcctgaaca ggatctattc gaggcgctga
     1861 gggaaacctt gaagctatgg aactcgcagc ccgactgggc cggcgatgag cgaaatgtag
     1921 tgcttacgtt gtcccgcatt tggtacagcg caataaccgg caaaatcgcg ccgaaggatg
     1981 tcgctgccga ctgggcaata aaacgcctac ctgcccagta tcagcccgtc ttacttgaag
     2041 ctaagcaagc ttatctggga caaaaagaag atcacttggc ctcacgcgca gatcacttgg
     2101 aagaatttat tcgctttgtg aaaggcgaga tcatcaagtc agttggtaaa tgatgtctaa
     2161 caattcgttc aagccgaccg cgctacgcgc ggcggcttaa ctccggcgtt agatgcacta
     2221 agcacataat tgctcacagc caaactatca ggtcaagtct gcttttatta tttttaagcg
     2281 tgcataataa gccctacaca aattgggaga tatatcatga aaggctggct ttttcttgtt
     2341 atcgcaatag ttggcgaagt aatcgcaaca tccgcattaa aatctagcga gggctttact
     2401 aagcttgccc cttccgccgt tgtcataatc ggttatggca tcgcatttta ttttctttct
     2461 ctggttctga aatccatccc tgtcggtgtt gcttatgcag tctggtcggg actcggcgtc
     2521 gtcataatta cagccattgc ctggttgctt catgggcaaa agcttgatgc gtggggcttt
     2581 gtaggtatgg ggctcataat tgctgccttt ttgctcgccc gatccccatc gtggaagtcg
     2641 ctgcggaggc cgacgccatg gtgacggtgt tcggcattct gaatctcacc gaggactcct
     2701 tcttcgatga gagccggcgg ctagaccccg ccggcgctgt caccgcggcg atcgaaatgc
     2761 tgcgagtcgg atcagacgtc gtggatgtcg gaccggccgc cagccatccg gacgcgaggc
     2821 ctgtatcgcc ggccgatgag atcagacgta ttgcgccgct cttagacgcc ctgtccgatc
     2881 agatgcaccg tgtttcaatc gacagcttcc aaccggaaac ccagcgctat gcgctcaagc
     2941 gcggcgtggg ctacctgaac gatatccaag gatttcctga ccctgcgctc tatcccgata
     3001 ttgctgaggc ggactgcagg ctggtggtta tgcactcagc gcagcgggat ggcatcgcca
     3061 cccgcaccgg tcaccttcga cccgaagacg cgctcgacga gattgtgcgg ttcttcgagg
     3121 cgcgggtttc cgccttgcga cggagcgggg tcgctgccga ccggctcatc ctcgatccgg
     3181 ggatggaccg gcgattggtc catggcgaaa cggccgacct tgcgccgacc ggcttcgggc
     3241 aacaggtccg cgaagccatg gaccagcgcc gcgagcatca tatcgaacag cgcgacgcca
     3301 cgcgcaacag ggacggccga atcttctacc ggcgcaatct tctcgccacc ctgcgcgagc
     3361 gggaagttgc gcgcgccggt gcggagatgg ccgagggcaa ggcgctgccg ttccgcgccg
     3421 ccaaggatgg tgagagcgtc agcggcaagt ttaccggaac cgtgcatcta tcgagcggca
     3481 agttcgccgt ggtcgagaaa tcccatgagt tcacccttgt cccgtggcgg ccgatcatcg
     3541 accgccaact cggccgcgag gttatgggca tcgtgcaggg cgggtcggtg tcgtggcagt
     3601 tagggcggca gagggggctg gaacgctgag tgcgcccatg ccgcattgcg aagcaaaaga
     3661 taatcggata aaatgtagca attcatattc gtaagcgtgg agtaatcaga tgggaaattc
     3721 caagtcagca gacaagtaag ccgcaacaac cagtattgtt gttgcggcgc tctgtaaggc
     3781 tagtctcatc tgattgctga cgagcagacg tcgcccggta ttccttaatc gagggttgat
     3841 tcgtcatgac caccacacgc cccgcgtggg cctatacgct gccggcagca ctgctgctga
     3901 tggctccttt cgacatcctc gcttcactgg cgatggatat ttatctccct gtcgttccag
     3961 cgatgcccgg catcctgaac acgacgcccg ctatgatcca actcacgttg agcctctata
     4021 tggtgatgct cggcgtgggc caggtgattt ttggtccgct ctcagacaga atcgggcgac
     4081 ggccaattct acttgcgggc gcaacggctt tcgtcattgc gtctctggga gcagcttggt
     4141 cttcaactgc accggccttt gtcgctttcc gtctacttca agcagtgggc gcgtcggcca
     4201 tgctggtggc gacgttcgcg acggttcgcg acgtttatgc caaccgtcct gagggtgtcg
     4261 tcatctacgg ccttttcagt tcgatgctgg cgttcgtgcc tgcgctcggc cctatcgccg
     4321 gagcattgat cggcgagttc ttgggatggc aggcgatatt cattactttg gctatactgg
     4381 cgatgctcgc actcctaaat gcgggtttca ggtggcacga aacccgccct ctggatcaag
     4441 tcaagacgcg ccgatctgtc ttgccgatct tcgcgagtcc ggctttttgg gtttacactg
     4501 tcggctttag cgccggtatg ggcaccttct tcgtcttctt ctcgacggct ccccgtgtgc
     4561 tcataggcca agcggaatat tccgagatcg gattcagctt tgccttcgcc actgtcgcgc
     4621 ttgtaatgat cgtgacaacc cgtttcgcga agtcctttgt cgccagatgg ggcatcgcag
     4681 gatgcgtggc gcgtgggatg gcgttgcttg tttgcggagc ggtcctgttg gggatcggcg
     4741 aactttacgg ctcgccgtca ttcctcacct tcatcctacc gatgtgggtt gtcgcggtcg
     4801 gtattgtctt cacggtgtcc gttaccgcga acggcgcttt ggcagagttc gacgacatcg
     4861 cgggatcagc ggtcgcgttc tacttctgca tccaaagcct gatagtcagt atcgtcggga
     4921 cattggcggt gacgctgtta aacggcgata cagcgtggcc cgtgatttgt tacgccacgg
     4981 caatggcagt gctggtgtcg ttggggctgg cgctccttcg atcccgtgat gctgccaccg
     5041 agaagtcgcc agtcgtctag ccgacgactg gaagcaagcc cgctccgatg cggcgcaata
     5101 atcttcgaaa cctcgtgaat ggcggtatcc tgtctggcaa gataccgctc atttcccttg
     5161 tcccgtggcg gccggtcatc gaccgccagc tcggccgtga ggtcatgggc atcgtgcaaa
     5221 gcggatcggt gtcgtggcag ttggggcggc aaaggggcat aagcctctaa tctgttgtag
     5281 atgaacgcag ccgctcgaaa ccagcgatga ggctgtcgag tccgaagttg aacgcagcat
     5341 ccatgccgtc tgtttccaac tcgtgaaaca gatcgtgcag gaaggacgac ggtgcttgct
     5401 cggacacatc tggcctgtcc ggaactctct catcggcatc agatgcctgc tgctcgagaa
     5461 cggaaccgac cacatagtga ctgaccgccc ggagcgccca aacggcgcgc ttcggacaaa
     5521 agccctccgc gcagagaaag cgtatttgcg tctcggcggt gccaaaattc ggttctgtcg
     5581 gtcgagtgcc ggcatggata cgcgcgccgt cccgataaga gagcaacgcc gttctgaagc
     5641 tcagggcatt ctctttcagg aacacccgcc agtcctcatt ctcttcgggt agcgagcggg
     5701 tatggcgttc cgccagcatc gcctcggcga gcgcatcaag cagcgctcgc ttgttctgga
     5761 aatgccagta aagcgcaggc tgctgaacct tgaggcgttc agcgagcttc cgcgtcgtca
     5821 ggctgtccat gccaacctcg ttcaacagct ctagcgccgc cgcgatcacg gtgcccttgt
     5881 ccagtttggt cattcacgtt ccttcgccag tgcttgacaa tttatcaccg ataagttata
     5941 tgtccatctc cttatcgttg ataaagtcgc tccattgagc ggcgctggag tttcaggtgc
     6001 gcagctctgc catcattgcc ctgctgatcg tgggtcttga cgccatgggt ctcggcctca
     6061 tcatgcccgt ccttccgacg cttctgcgtg agcttgtgcc agcagagcag gtcgctggac
     6121 actatggtgc cttgctgtcg ctctatgcat tgatgcaggt cgtcttcgcg cccatgcttg
     6181 gacagctttc ggattcttac ggtcggcgtc cggtacttct ggcttctctt gcaggagccg
     6241 cagtcgatta cacgattatg gcatcagcgc cggtcttatg ggtgctctat atcggccgac
     6301 tcgtgtccgg cgtcacgggc gcaaccggag ctgtagcagc ctcaaccatt gccgattcga
     6361 cgggggaagg ttctcgcgca cgctggttcg gctacatggg ggcctgttat ggggcgggca
     6421 tgattgccgg gccagcactt ggtggcatgc tcggtggtat ctctgctcat gccccgttta
     6481 tcgccgccgc ccttctcaac gggttcgcgt tcctgcttgc ctgcattttc ctcaaggaga
     6541 ctcatcacag ccatggcggg accggaaagc cggttcgcat caaaccattc gttctgttac
     6601 ggctggatga tgcattgcgc gggctaggtg cgcttttcgc agttttcttc attattcaac
     6661 tgatcggcca agtgcctgca gccctatggg tcatatatgg cgaggaccgt tttcagtgga
     6721 acaccgcgac cgttggtttg tcgctcgcgg cgtttggggc aacacatgcg atcttccaag
     6781 cgtttgttac cggcccgctt tcaagccggc ttggagagcg gcgcacgctg ctgtttggca
     6841 tggctgcgga tgcgactggc ttcgttcttc tggcttttgc cacgcaggga tggatggtgt
     6901 tcccgattct gttgctgctt gccgccgggg gtgttggcat gccggccttg caggcaatgc
     6961 tctcaaacaa tgtcagcagt aacaagcaag gggctttgca aggaacgcta acgagcctca
     7021 ccaatctaag ctctatcgca ggaccgcttg gcttcacagc actctattct gccaccgccg
     7081 gggcatggaa cggttgggtt tggattgtcg gcgcgatcct ctatttaata tgtctgccaa
     7141 tactacgcag accattcgca acttcattgt gatttagtca tggcgatttg gcatgcgtag
     7201 acttaggaga aatgacggat taaatctgtt gagcaatcat ctcctttcgg ggcgagtgcc
     7261 aatgatgacc ttagttcaca ctctcgctgt cgccgaatat ctcaacttcc gtcacgccgc
     7321 caacgcgctc ggcgttgcac agtccagcgt cagcgcccgc gtgaaggcac tggaagaaga
     7381 cctcggcatc ctcttgttcg agcgtcatgc gcgcggcgtt cggctgaccg aggccggacg
     7441 ccatttcgtc gagcggatag ccgtaggtat tgaccaactc gaccatgcgg tgaaaaccgc
     7501 cggcatggcg gcagccggag aaagcggccg gcttcgtatc ggtatccatg ccctgattcc
     7561 gcatagcttc ctcgcaaagc tgatcggcca ataccgcaag gattaccccg atgttgaagt
     7621 cgagatcgcc gaaggcccgg cccgtgaagc ggtggtgcag cttcgcgccg gcaggttgga
     7681 cgtggcgttc gtcgcgggca cgccccaacc acccgactgc cattcccgtc gcacatggac
     7741 cgaaccgctc ttggcggtgc taccggaacg gcatccgctc gccaagcggt cagccgtcac
     7801 atggcccgat ttggcaggcg agacgttcct tgcgtatagg aagttcaaac gcccttttcg
     7861 ggcagtctgc tgggtaggcg gcggtcgcgc aagccccgtt ttgggcacgg atcggacgtc
     7921 tgtgagtggg atttcggcat cgcggggcca cgcagcggcg ttgtcagcag ccatgcttcg
     7981 ctgattcccg acagcgggcc gagcgccgcc ctgcggatcg tggccgcatc ggctcggatt
     8041 ccggtttcgc cgtcggctgt gcagccggca gatcgtcacg cggcttgcac tggcggcgcg
     8101 cgcgctgcgg gcctgtagtg cgcttcttcc cgcgcgccgt gcttctcgaa gtgggcgagg
     8161 atggcgcgga tggcggtggg ttcctcgatg ctggcgacga tccgcacggt gccaccgcag
     8221 tggacgcagg cggtgacgtc gatggaaaag acccgcttga gccgttgcgc ccagctcatc
     8281 gcacggcgct tctcctcggg gctgcgcggc gcgtcgtggg cgctgacgtc cactggcgcc
     8341 gcatcgcccg caggccgctt gccgcgcccc gagggcgtca gctgcgcacg caggtttgca
     8401 ttcggggcga atacgccgtg gaagcgggtg agatgcgcgc gaggtggcgg gaccagcgcc
     8461 gccagcttgg cgatgaaatc caccggatcc cattccacat gcgtggtgcc attgcgccac
     8521 ggggtcttga gctggtaacg caccctgccc tggagcgcta tcgacagccg cttctcgctg
     8581 atcgccgggc gcgtgatgta gcggcacagc ttttccagct tgtggctttc gtgtgcttcg
     8641 gccgccacgc cggcatgcag tgagaagccg ccgaccttgc cggcttcgcc ctccagcgaa
     8701 ccggcgtcac cgggcagcgt ttgcagcgtg acgaccttgc agccagcgtc gcggccggtg
     8761 gcgatgcggt aggtgatcga actcatccgc agcccatcca tgctgtcgtc gcctgcagcg
     8821 ctgtctgcca ggaaggccga ttcgccctcc ccttcgagcc agcctttgcg cgtcaggtgc
     8881 cgacacaccc ggtgcgcgat ggtagctgcc agctgggtca actgcgcggt ggtgggcgca
     8941 cgggcgcggt gcaggcgcag ttcgcgccgc ggcagctcgg tggcttccac gtacacgccg
     9001 tcgagccaca gcatgtggaa gtggatgttc aggttcagcg cgctgccgaa acgctggatc
     9061 agcgtcaccg cgccgcactg ggcgctggcg cggtcgatgc cggcttgatc ggccaaccag
     9121 ccggcgatca cgcgctgcac gatgcccagc accgggccaa tggcttctgg cttgctggcg
     9181 aacaggaaac gcaaggggta cggaaagctc agcacccatt gccgcacagg ccgcgggccg
     9241 aacacctcct cgaccaggtg ccgcgcactc tcggccatgc gtcgcgcgcc gcaactcggg
     9301 cagaacccgc gcttcttgca ggagaaggcc accagcctct ctgcacggca gtgctcgcac
     9361 accacccgca ggaagccgtg ctcgagtacg ccgcaacgca ggtaggcatc gaacgcctcg
     9421 cggacatacc cgggcagcga gcggccctcc gcttcgatcc gtgcaatgaa gtccgggtag
     9481 tgcgcctcta ccaacgcgta cagcagcgtg cgctcgggcg cgtggcgcgc gtaccgcgaa
     9541 ccggtgtggg cggacggcag tggcgcgcat cccgcggctt gccgccggga tgtggcgagg
     9601 cgcggcacgc agcgctccgg tgcggggacg gctgctcagt gttgcgcctg tgttcgcacg
     9661 ttcgtatcgg tgcgttctga tcttcgcgtc agacattgcc gcggcgcggg cacaacaaaa
     9721 agcccggcat cgctgccggg ctccggcccc gtccttgggg ccttgatgtc gggtcgttgc
     9781 cgggatcgga ccgcgctggc gcggtccggt tccctgacga ccgggccaac cggatcagaa
     9841 atccatgccg cccatgccgc ccataccgcc agcacccggc atggccggct cttccttctt
     9901 cggcacttcg gccacgacca cttcggtcgt gatcgcaagg ccggcgacgg aagcggcgtg
     9961 ctgcagggcc gagcgggtca ccttggtcgg gtccaggatg cccatggcga tcatgtcgcc
    10021 gaactcgccg gtggcggcgt tgtagccgta gctgccttcg ccggccttga cgttggccac
    10081 gatcacgctc ggttcttcac cggcgttggc cacgatggcg cgcagcgggg cttccagcgc
    10141 acggcgggtg atggcgatgc ccaggttctg gtcttcgttg atgccctgcc agggcagatc
    10201 cgtgcacagc accttgccgt agaagaacag caaggccgcc aatgcctgac gatgcgtgga
    10261 gaccgaaacc ttgcgctcgt tcgccagcca ggacagaaat gcctcgactt cgctgctgcc
    10321 caaggttgcc gggtgacgca caccgtggaa acggatgaag gcacgaaccc agtggacata
    10381 agcctgttcg gttggtaagc tgtaatgcaa gtagcgtatg cgctcacgca actggtccag
    10441 aaccttgacc gaacgcagcg gtggtaacgg cgcagtggcg gttttcatgg cttgttatga
    10501 ctgttttttt gtacagtcta tgcctcgggc atccaagcag caagcgcgtt acgccgtggg
    10561 tcgatgtttg atgttatgga gcagcaacga tgttacgcag cagggcagtc gccctaaaac
    10621 aaagttagcc atattatgga gcctcatgct tttatataaa atgtgtgaca atcaaaatta
    10681 tggggttact tacatgaagt ttttattggc attttcgctt ttaataccat ccgtggtttt
    10741 tgcaagtagt tcaaagtttc agcaagttga acaagacgtt aaggcaattg aagtttctct
    10801 ttctgctcgt ataggtgttt ccgttcttga tactcaaaat ggagaatatt gggattacaa
    10861 tggcaatcag cgcttcccgt taacaagtac ttttaaaaca atagcttgcg ctaaattact
    10921 atatgatgct gagcaaggaa aagttaatcc caatagtaca gtcgagatta agaaagcaga
    10981 tcttgtgacc tattcccctg taatagaaaa gcaagtaggg caggcaatca cactcgatga
    11041 tgcgtgcttc gcaactatga ctacaagtga taatactgcg gcaaatatca tcctaagtgc
    11101 tgtaggtggc cccaaaggcg ttactgattt tttaagacaa attggggaca aagagactcg
    11161 tctagaccgt attgagcctg atttaaatga aggtaagctc ggtgatttga gggatacgac
    11221 aactcctaag gcaatagcca gtactttgaa taaattttta tttggttccg cgctatctga
    11281 aatgaaccag aaaaaattag agtcttggat ggtgaacaat caagtcactg gtaatttact
    11341 acgttcagta ttgccggcgg gatggaacat tgcggatcgc tcaggtgctg gcggatttgg
    11401 tgctcggagt attacagcag ttgtgtggag tgagcatcaa gccccaatta ttgtgagcat
    11461 ctatctagct caaacacagg cttcaatggc agagcgaaat gatgcgattg ttaaaattgg
    11521 tcattcaatt tttgacgttt atacatcaca gtcgcgctga taaggctaac aaggccatca
    11581 agttgacggc ttttccgtcg cttgttttgt ggtttaacgc tacgctacca caaaacaatc
    11641 aactccaaag ccgcaactta tggcggcgtt agatgcacta agcacataat tgctcacagc
    11701 caaactatca ggtcaagtct gcttttatta tttttaagcg tgcataataa gccctacaca
    11761 aattgggaga tatatcatga aaggctggct ttttcttgtt atcgcaatag ttggcgaagt
    11821 aatcgcaaca tccgcattaa aatctagcga gggctttact aagcttgccc cttccgccgt
    11881 tgtcataatc ggttatggca tcgcatttta ttttctttct ctggttctga aatccatccc
    11941 tgtcggtgtt gcttatgcag tctggtcggg actcggcgtc gtcataatta cagccattgc
    12001 ctggttgctt catgggcaaa agcttgatgc gtggggcttt gtaggtatgg ggctcataat
    12061 tgctgccttt ttgctcgccc gatccccatc gtggaagtcg ctgcggaggc cgacgccatg
    12121 gtgacggtgt tcggcattct gaatctcacc gaggactcct tcttcgatga gagccggcgg
    12181 ctagaccccg ccggcgctgt caccgcggcg atcgaaatgc tgcgagtcgg atcagacgtc
    12241 gtggatgtcg gaccggccgc cagccatccg gacgcgaggc ctgtatcgcc ggccgatgag
    12301 atcagacgta ttgcgccgct cttagacgcc ctgtccgatc agatgcaccg tgtttcaatc
    12361 gacagcttcc aaccggaaac ccagcgctat gcgctcaagc gcggcgtggg ctacctgaac
    12421 gatatccaag gatttcctga ccctgcgctc tatcccgata ttgctgaggc ggactgcagg
    12481 ctggtggtta tgcactcagc gcagcgggat ggcatcgcca cccgcaccgg tcaccttcga
    12541 cccgaagacg cgctcgacga gattgtgcgg ttcttcgagg cgcgggtttc cgccttgcga
    12601 cggagcgggg tcgctgccga ccggctcatc ctcgatccgg ggatgggatt tttcttgagc
    12661 cccgcaccgg aaacatcgct gcacgtgctg tcgaaccttc aaaagctgaa gtcggcgttg
    12721 gggcttccgc tattggtctc ggtgtcgcgg aaatccttct tgggcgccac cgttggcctt
    12781 cctgtaaagg atctgggtcc agcgagcctt gcggcggaac ttcacgcgat cggcaatggc
    12841 gctgactacg tccgcaccca cgcgcctgga gatctgcgaa gcgcaatcac cttctcggaa
    12901 accctcgcga aatttcgcag tcgcgacgcc agagaccgag ggttagatca tgcctagcat
    12961 tcaccttccg gccgcccgct agcggaccct ggtcaggttc cgcgaaggtg ggcgcagaca
    13021 tgctgggctc gtcaggatca aactgcacta tgaggcggcg gttcataccg cgccagggga
    13081 gcgaatggac agcgaggagc ctccgaacgt tcgggtcgcc tgctcgggtg atatcgacga
    13141 ggttgtgcgg ctgatgcacg acgctgcggc gtggatgtcc gccaagggaa cgcccgcctg
    13201 ggacgtcgcg cggatcgacc ggacattcgc ggagaccttc gtcctgagat ccgagctcct
    13261 agtcgcgagt tgcagcgacg gcatcgtcgg ctgttgcacc ttgtcggccg aggatcccga
    13321 gttctggccc gacgccctca agggggaggc cgcatatctg cacaagctcg cggtgcgacg
    13381 gacacatgcg ggccggggtg tcagctccgc gctgatcgag gcttgccgcc atgccgcgcg
    13441 aacgcagggg tgcgccaagc tgcggctcga ctgccacccg aacctgcgtg gcctatacga
    13501 gcggctcgga ttcacccacg tcgacacttt caatcccggc tgggatccaa ccttcatcgc
    13561 agaacgccta gaactcgaaa tctaacgtcc gttcgggcat cgaggtccat gtcggggtgg
    13621 gacgggcccg tggcttcaag atcacttgca gtccgaccgc gatgtcttgg ttgcgcgaga
    13681 ggttgtcgat atcctccact tccatcatca accctggata atgccgccgc cgtcatcgcc
    13741 gccgacgccc gtgccgggct tttcgggcct gtcaggcttg ctcggccttc agcctgcctg
    13801 ggcgagatct ccggcggacg gattaacggc ggagcttcgc cgcctttcgt gcgtgtgaag
    13861 gccgaagata gttctctcaa aaacatccgt ttatgagaga taccaaatgt cattttcaga
    13921 agacgactgc accagttgat tgggcgtaat ggctgttgtg cagccagctc ctgacagttc
    13981 aatatcagaa gtgatctgca ccaatctcga ctatgctcaa tactcgtgtg ggctctgttg
    14041 caaaaatcgt gaagcttgag catgcttggc ggagattgga cggacggaac gatgacggat
    14101 ttcaagtggc gccatttcca gggtgatgtg atcctgtggg cggtgcgctg gtattgtcgc
    14161 tatccgatca gctatcgcga ccttgaggaa atgctggcgg aacgcggcat ttcggtcgac
    14221 catacgacga tctatcgctg ggtccagtgc tacgccccgg agatggagaa gcggctgcgc
    14281 tggttctggc ggcgtggctt tgatccgagc tggcgcctgg atgaaaccta cgtcaaggtg
    14341 cggggcaagt ggacctacct gtaccgggca gtcgacaagc ggggcgacac gatcgatttc
    14401 tacctgtcgc cgacccgcag cgccaaggca gcgaagcggt tcctgggcaa ggccctgcga
    14461 ggcctgaagc actgggaaaa gcctgccacg ctcaataccg acaaagcgcc gagctatggt
    14521 gcagcgatca ccgaattgaa gcgcgaagga aagctggacc gggagacggc ccaccggcag
    14581 gtgaagtatc tcaataacgt gatcgaggcc gatcacggaa agctcaagat actgatcaag
    14641 ccggtgcgcg gtttcaaatc gatccccacg gcctatgcca cgatcaaggg attcgaagtc
    14701 atgcgagccc tgcgcaaagg acaggctcgc ccctggtgcc tgcagcccgg catcaggggc
    14761 gaggtgcgcc ttgtggagag agcttttggc attgggccct cggcgctgac ggaggccatg
    14821 ggcatgctca accaccattt cgcagcagcc gcctgatcgg cgcagagcga cagcctacct
    14881 ctgactgccg ccaatctttg caacagagcc tccgtcgcca tgctcacctc gctttggtgc
    14941 acacgagtat tgagcatagt cgagattggt gcagatcact tctgatattg aactgtcagg
    15001 agctggctgc acaacagcca ttacgcccaa tcaactggtg cagtcgtctt ctgaaaatga
    15061 ca
//
